CORDIS
EU research results

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Investigating the impact of meditation training on mental health and wellbeing in the ageing population

Project information

Grant agreement ID: 667696

Status

Ongoing project

  • Start date

    1 January 2016

  • End date

    31 December 2020

Funded under:

H2020-EU.3.1.4.

  • Overall budget:

    € 7 087 230,46

  • EU contribution

    € 6 134 756,25

Coordinated by:

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

Objective

As the number of older people in Europe grows, increasing healthy life years is a priority. Cognitive decline, dementia (e.g. Alzheimer’s disease, AD), sleep disturbances and depression, all related to psychological distress and anxiety, are significant drivers of reduced quality of life in older adults. This project builds on evidence that lifestyle factors and meditation practice have the potential to downregulate these adverse factors and positively impact mental and neurological conditions including AD. Our main objectives are i) to improve early AD detection and understanding of physiopathological mechanisms; and to investigate ii) the impact of internal/external (e.g. genetic and lifestyle) determinants and iii) the effect and mechanisms of action of meditation training, on mental health and wellbeing in older people. This will be achieved by using pre-existing databases from European partners and conducting two randomized controlled trials (Studies 1 and 2B) and one observational study (2A). STUDY 1 will assess the short-term effects of an 8-week meditation intervention (versus cognitive training) in patients with subjective cognitive decline at risk for AD on behavioural measures including anxiety and wellbeing. STUDY 2A will assess senior expert meditators to identify neural signatures of different meditation practices on attention and emotion regulation tasks. STUDY 2B will assess long-term effects of an 18-month meditation intervention (versus an active control) on behavioural and biological markers of mental health and wellbeing in cognitively intact elderly. The cognitive and affective regulatory mechanisms underlying these effects will be investigated using the neural signatures identified in the expert meditators. High public health relevance is likely: the proposed intervention targets the most common mental and neurological conditions in the elderly and it can be scaled up within preventive programmes at a population level.

Coordinator

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

Address

Rue De Tolbiac 101
75654 Paris

France

Activity type

Research Organisations

EU Contribution

€ 4 226 379,50

Participants (10)

UNIVERSITE DE LIEGE

Belgium

EU Contribution

€ 276 250

UNIVERSITE DE GENEVE

Switzerland

UNIVERSITY COLLEGE LONDON

United Kingdom

EU Contribution

€ 611 893,25

KLINIKUM DER UNIVERSITAET ZU KOELN

Germany

EU Contribution

€ 95 000

HOSPICES CIVILS DE LYON

France

EU Contribution

€ 100 500

CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER

Spain

EU Contribution

€ 101 437,50

ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK

France

EU Contribution

€ 110 875

INSERM - TRANSFERT SA

France

EU Contribution

€ 139 175

MINERVA HEALTH & CARE COMMUNICATIONS LTD

United Kingdom

EU Contribution

€ 412 875

THE UNIVERSITY OF EXETER

United Kingdom

EU Contribution

€ 60 371

Project information

Grant agreement ID: 667696

Status

Ongoing project

  • Start date

    1 January 2016

  • End date

    31 December 2020

Funded under:

H2020-EU.3.1.4.

  • Overall budget:

    € 7 087 230,46

  • EU contribution

    € 6 134 756,25

Coordinated by:

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France