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Ubiquitous Pharmacogenomics (U-PGx): Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen

Ubiquitous Pharmacogenomics (U-PGx): Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen

Objective

Pharmacogenomics is the study of genetic variability affecting an individual’s response to a drug. Its use allows personalized medicine and reduction in ‘trial and error’ prescribing leading to more efficacious, safer and cost-effective drug therapy. The U-PGx consortium will investigate a pre-emptive genotyping approach (that is: multiple pharmacogenomic variants are collected prospectively and embedded into the patients’ electronic record) of a panel of important pharmacogenomic variants as a new model of personalised medicine. To meet this goal we combine existing pharmacogenomics guidelines and novel health IT solutions. Implementation will be conducted at a large scale in seven existing European health care environments and accounts for the diversity in health system organisations and settings. Feasibility, health outcome and cost-effectiveness will be investigated. We will formulate European strategies for improving clinical implementation of pharmacogenomics based on the findings of this project.

Coordinator

ACADEMISCH ZIEKENHUIS LEIDEN

Address

Albinusdreef 2
2333 Za Leiden

Netherlands

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 2 881 388,75

Participants (16)

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THE UNIVERSITY OF LIVERPOOL

United Kingdom

EU Contribution

€ 1 078 330

BUNDESINSTITUT FUR ARZNEIMITTEL UND MEDIZINPRODUKTE

Germany

EU Contribution

€ 393 125

KAROLINSKA INSTITUTET

Sweden

EU Contribution

€ 665 112,50

THE GOLDEN HELIX FOUNDATION

United Kingdom

EU Contribution

€ 706 250

KNMP HOLDING B.V.

Netherlands

EU Contribution

€ 1 136 108,25

BIO.LOGIS GENETIC INFORMATION MANAGEMENT GMBH

Germany

EU Contribution

€ 2 316 125

STICHTING SINT ANTONIUS ZIEKENHUIS

Netherlands

EU Contribution

€ 8 610,74

MEDIZINISCHE UNIVERSITAET WIEN

Austria

EU Contribution

€ 1 429 783,75

UNIVERSITE PAUL SABATIER TOULOUSE III

France

EU Contribution

€ 280 055

UPPSALA UNIVERSITET

Sweden

EU Contribution

€ 294 583,75

CENTRO DI RIFERIMENTO ONCOLOGICO DI AVIANO

Italy

EU Contribution

€ 875 380

SERVICIO ANDALUZ DE SALUD

Spain

EU Contribution

€ 810 937,50

PANEPISTIMIO PATRON

Greece

EU Contribution

€ 909 375

UNIVERZA V LJUBLJANI

Slovenia

EU Contribution

€ 430 825

ROBERT BOSCH GESELLSCHAFT FUR MEDIZINISCHE FORSCHUNG MBH

Germany

EU Contribution

€ 561 393,75

UNIVERSITAIR MEDISCH CENTRUM UTRECHT

Netherlands

EU Contribution

€ 159 229,26

Project information

Grant agreement ID: 668353

Status

Ongoing project

  • Start date

    1 January 2016

  • End date

    31 December 2020

Funded under:

H2020-EU.3.1.6.

  • Overall budget:

    € 14 936 613,25

  • EU contribution

    € 14 936 613,25

Coordinated by:

ACADEMISCH ZIEKENHUIS LEIDEN

Netherlands