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Ubiquitous Pharmacogenomics (U-PGx): Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen

Objective

Pharmacogenomics is the study of genetic variability affecting an individual’s response to a drug. Its use allows personalized medicine and reduction in ‘trial and error’ prescribing leading to more efficacious, safer and cost-effective drug therapy. The U-PGx consortium will investigate a pre-emptive genotyping approach (that is: multiple pharmacogenomic variants are collected prospectively and embedded into the patients’ electronic record) of a panel of important pharmacogenomic variants as a new model of personalised medicine. To meet this goal we combine existing pharmacogenomics guidelines and novel health IT solutions. Implementation will be conducted at a large scale in seven existing European health care environments and accounts for the diversity in health system organisations and settings. Feasibility, health outcome and cost-effectiveness will be investigated. We will formulate European strategies for improving clinical implementation of pharmacogenomics based on the findings of this project.

Call for proposal

H2020-PHC-2015-two-stage
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

ACADEMISCH ZIEKENHUIS LEIDEN
Address
Albinusdreef 2
2333 ZA Leiden
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 881 388,75

Participants (16)

THE UNIVERSITY OF LIVERPOOL
United Kingdom
EU contribution
€ 1 078 330
Address
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool
Activity type
Higher or Secondary Education Establishments
BUNDESINSTITUT FUR ARZNEIMITTEL UND MEDIZINPRODUKTE

Participation ended

Germany
EU contribution
€ 393 125
Address
Kurt Georg Kiesinger Allee 3
53175 Bonn
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 665 112,50
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
THE GOLDEN HELIX FOUNDATION
United Kingdom
EU contribution
€ 706 250
Address
16 Northumberland Avenue Craven House
WC2N 5AP London
Activity type
Research Organisations
KNMP HOLDING B.V.
Netherlands
EU contribution
€ 1 136 108,25
Address
Alexanderstraat 11
2500 GL Den Haag
Activity type
Other
BIO.LOGIS GENETIC INFORMATION MANAGEMENT GMBH
Germany
EU contribution
€ 2 316 125
Address
Altenhoferallee 3
60438 Frankfurt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
STICHTING SINT ANTONIUS ZIEKENHUIS

Participation ended

Netherlands
EU contribution
€ 8 610,74
Address
Koekoekslaan 1
3435 CM Nieuwegein
Activity type
Research Organisations
MEDIZINISCHE UNIVERSITAET WIEN
Austria
EU contribution
€ 1 429 783,75
Address
Spitalgasse 23
1090 Wien
Activity type
Higher or Secondary Education Establishments
UNIVERSITE PAUL SABATIER TOULOUSE III
France
EU contribution
€ 280 055
Address
Route De Narbonne 118
31062 Toulouse Cedex 9
Activity type
Higher or Secondary Education Establishments
UPPSALA UNIVERSITET
Sweden
EU contribution
€ 294 583,75
Address
Von Kraemers Alle 4
751 05 Uppsala
Activity type
Higher or Secondary Education Establishments
CENTRO DI RIFERIMENTO ONCOLOGICO DI AVIANO
Italy
EU contribution
€ 875 380
Address
Via Franco Gallini 2
33081 Aviano Pn
Activity type
Research Organisations
SERVICIO ANDALUZ DE SALUD
Spain
EU contribution
€ 810 937,50
Address
Avenida De La Constitucion 18
41071 Sevilla
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
PANEPISTIMIO PATRON
Greece
EU contribution
€ 909 375
Address
University Campus Rio Patras
265 04 Rio Patras
Activity type
Higher or Secondary Education Establishments
UNIVERZA V LJUBLJANI
Slovenia
EU contribution
€ 430 825
Address
Kongresni Trg 12
1000 Ljubljana
Activity type
Higher or Secondary Education Establishments
ROBERT BOSCH GESELLSCHAFT FUR MEDIZINISCHE FORSCHUNG MBH
Germany
EU contribution
€ 561 393,75
Address
Auerbachstrasse 112
70376 Stuttgart
Activity type
Research Organisations
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
EU contribution
€ 159 229,26
Address
Heidelberglaan 100
3584 CX Utrecht
Activity type
Higher or Secondary Education Establishments