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Ubiquitous Pharmacogenomics (U-PGx): Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen

Objective

Pharmacogenomics is the study of genetic variability affecting an individual’s response to a drug. Its use allows personalized medicine and reduction in ‘trial and error’ prescribing leading to more efficacious, safer and cost-effective drug therapy. The U-PGx consortium will investigate a pre-emptive genotyping approach (that is: multiple pharmacogenomic variants are collected prospectively and embedded into the patients’ electronic record) of a panel of important pharmacogenomic variants as a new model of personalised medicine. To meet this goal we combine existing pharmacogenomics guidelines and novel health IT solutions. Implementation will be conducted at a large scale in seven existing European health care environments and accounts for the diversity in health system organisations and settings. Feasibility, health outcome and cost-effectiveness will be investigated. We will formulate European strategies for improving clinical implementation of pharmacogenomics based on the findings of this project.

Call for proposal

H2020-PHC-2014-2015

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Sub call

H2020-PHC-2015-two-stage

Coordinator

ACADEMISCH ZIEKENHUIS LEIDEN
Net EU contribution
€ 2 881 388,75
Address
Albinusdreef 2
2333 ZA Leiden
Netherlands

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Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Higher or Secondary Education Establishments
Other funding
€ 2 881 388,75

Participants (21)

THE UNIVERSITY OF LIVERPOOL
United Kingdom
Net EU contribution
€ 481 737,94
Address
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool

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Region
North West (England) Merseyside Liverpool
Activity type
Higher or Secondary Education Establishments
Other funding
€ 481 737,94
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST
United Kingdom
Net EU contribution
€ 596 592,06
Address
Prescot Street
L7 8XP Liverpool

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Region
North West (England) Merseyside Liverpool
Activity type
Research Organisations
Other funding
€ 596 592,06
BUNDESINSTITUT FUR ARZNEIMITTEL UND MEDIZINPRODUKTE

Participation ended

Germany
Net EU contribution
€ 214 324,75
Address
Kurt Georg Kiesinger Allee 3
53175 Bonn
Region
Nordrhein-Westfalen Köln Bonn, Kreisfreie Stadt
Activity type
Research Organisations
Other funding
€ 214 324,75
KAROLINSKA INSTITUTET
Sweden
Net EU contribution
€ 665 112,50
Address
Nobels Vag 5
17177 Stockholm

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 665 112,50
THE GOLDEN HELIX FOUNDATION
United Kingdom
Net EU contribution
€ 706 250,00
Address
16 Northumberland Avenue Craven House
WC2N 5AP London

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Region
London Inner London — West Westminster
Activity type
Research Organisations
Other funding
€ 706 250,00
KNMP HOLDING B.V.
Netherlands
Net EU contribution
€ 1 136 108,25
Address
Alexanderstraat 11
2500 GL Den Haag

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Zuid-Holland Agglomeratie ’s-Gravenhage
Activity type
Other
Other funding
€ 1 136 108,25
BIO.LOGIS GENETIC INFORMATION MANAGEMENT GMBH

Participation ended

Germany
Net EU contribution
€ 2 059 398,44
Address
Altenhoferallee 3
60438 Frankfurt
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Darmstadt Frankfurt am Main, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 2 059 398,44
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

STEINBERGER DANIELA

Participation ended

Germany
Net EU contribution
€ 137 825,81
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 137 825,81
STICHTING SINT ANTONIUS ZIEKENHUIS

Participation ended

Netherlands
Net EU contribution
€ 8 610,74
Address
Koekoekslaan 1
3435 CM Nieuwegein
Region
West-Nederland Utrecht Utrecht
Activity type
Research Organisations
Other funding
€ 8 610,74
MEDIZINISCHE UNIVERSITAET WIEN
Austria
Net EU contribution
€ 1 429 783,75
Address
Spitalgasse 23
1090 Wien

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Region
Wien Wien
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 429 783,75
UNIVERSITE PAUL SABATIER TOULOUSE III
France
Net EU contribution
€ 244 430,00
Address
Route De Narbonne 118
31062 Toulouse Cedex 9

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Region
Occitanie Midi-Pyrénées Haute-Garonne
Activity type
Higher or Secondary Education Establishments
Other funding
€ 244 430,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 35 625,00
Address
Rue De Tolbiac 101
75654 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 35 625,00
UPPSALA UNIVERSITET
Sweden
Net EU contribution
€ 294 583,75
Address
Von Kraemers Alle 4
751 05 Uppsala

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Region
Östra Sverige Östra Mellansverige Uppsala län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 294 583,75
CENTRO DI RIFERIMENTO ONCOLOGICO DI AVIANO
Italy
Net EU contribution
€ 875 380,00
Address
Via Franco Gallini 2
33081 Aviano Pn

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Region
Nord-Est Friuli-Venezia Giulia Pordenone
Activity type
Research Organisations
Other funding
€ 875 380,00
SERVICIO ANDALUZ DE SALUD
Spain
Net EU contribution
€ 810 937,50
Address
Avenida De La Constitucion 18
41071 Sevilla

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Region
Andalucía Sevilla
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
€ 810 937,50
PANEPISTIMIO PATRON
Greece
Net EU contribution
€ 909 375,00
Address
University Campus Rio Patras
265 04 Rio Patras

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Region
Αχαΐα Δυτική Ελλάδα Κεντρική Ελλάδα
Activity type
Higher or Secondary Education Establishments
Other funding
€ 909 375,00
UNIVERZA V LJUBLJANI
Slovenia
Net EU contribution
€ 430 825,00
Address
Kongresni Trg 12
1000 Ljubljana

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Region
Slovenija Zahodna Slovenija Osrednjeslovenska
Activity type
Higher or Secondary Education Establishments
Other funding
€ 430 825,00
ROBERT BOSCH GESELLSCHAFT FUR MEDIZINISCHE FORSCHUNG MBH
Germany
Net EU contribution
€ 561 393,75
Address
Auerbachstrasse 112
70376 Stuttgart

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Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Research Organisations
Other funding
€ 561 393,75
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
Net EU contribution
€ 159 229,26
Address
Heidelberglaan 100
3584 CX Utrecht

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Region
West-Nederland Utrecht Utrecht
Activity type
Higher or Secondary Education Establishments
Other funding
€ 159 229,26
UNIVERSITAETSKLINIKUM AACHEN
Germany
Net EU contribution
€ 178 800,25
Address
Pauwelsstrasse 30
52074 Aachen

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Region
Nordrhein-Westfalen Köln Städteregion Aachen
Activity type
Higher or Secondary Education Establishments
Other funding
€ 178 800,25
BIO.LOGIS DIGITAL HEALTH GMBH
Germany
Net EU contribution
€ 118 900,75
Address
Altenhoferallee 3
60438 Frankfurt

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Region
Darmstadt Frankfurt am Main, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 118 900,75