Objective A hallmark symptom of posttraumatic stress disorder involves ‘recurrent, involuntary and intrusive memories of the traumatic event’, in their most extreme form referred to as ‘flashbacks’. At present, effective interventions to prevent the development of intrusive memory after trauma are lacking. The research aim is to develop innovative, science-based therapies for treating trauma-related psychiatric disorders, by using a multidisciplinary approach, combining advanced neuroimaging (fMRI) analyses with an experimental analogue for trauma (film footage with aversive content). Key to the proposed research are findings from basic neuroscience showing that consolidated memories can - upon their retrieval – enter a labile state, making them susceptible to interference. Recent finds from the supervisors lab show that the reconsolidation of trauma memory can be disrupted, resulting in fewer subsequent intrusions, by engaging participants in a visuospatial task (i.e. Tetris) after retrieving the memory. To understand the mechanisms underlying this effect, I aim to directly measure the neural processes involved in the modulation of consolidated emotional memory. This has the potential to yield major conceptual, clinical and methodological insights, and will advance my research skills. The acquired transferrable knowledge will form the basis of a future grant application fully supported by the supervisor, prof. Emily Holmes, towards the end of the fellowship and fuel my career as a future leader in mental health science. My training will include courses on advanced MRI, media training and project management, and disseminating my results through scientific papers, conferences, and the media. A fellowship at the Medical Research Council (MRC) Cognition and Brain Sciences Unit (CBU) in Cambridge would help me establish an network with leading scientists from all over the world, while being based at a premier establishment for clinical psychology research and neuroscience. Fields of science natural sciencesbiological sciencesneurobiologycognitive neurosciencesocial sciencespsychologypsychotherapymedical and health scienceshealth sciencesmedical and health sciencesclinical medicinepsychiatryposttraumatic stress disordersocial sciencespsychologycognitive psychology Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) Call for proposal H2020-MSCA-IF-2015 See other projects for this call Funding Scheme MSCA-IF-EF-ST - Standard EF Coordinator THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Net EU contribution € 114 015,30 Address TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge United Kingdom See on map Region East of England East Anglia Cambridgeshire CC Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 114 015,30 Participants (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNITED KINGDOM RESEARCH AND INNOVATION Participation ended United Kingdom Net EU contribution € 81 439,50 Address POLARIS HOUSE NORTH STAR AVENUE SN2 1FL Swindon See on map Region South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Swindon Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 81 439,50