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Role of autonomous B cell receptor signalling and external antigen in the pathogenesis of chronic lymphocytic leukaemia (CLL)

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PI3K induces B-cell development and regulates B cell identity

Author(s): Hend Abdelrasoul, Markus Werner, Corinna S. Setz, Klaus Okkenhaug, Hassan Jumaa
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
DOI: 10.1038/s41598-018-19460-5

Differences in Self-Recognition between Secreted Antibody and Membrane-Bound B Cell Antigen Receptor

Author(s): Joseena Iype, Moumita Datta, Ahmad Khadour, Rudolf Übelhart, Antonella Nicolò, Tim Rollenske, Marcus Dühren-von Minden, Hedda Wardemann, Palash C. Maity, Hassan Jumaa
Published in: The Journal of Immunology, Issue 202/5, 2019, Page(s) 1417-1427, ISSN 0022-1767
DOI: 10.4049/jimmunol.1800690

Isotype Specific Assembly of B Cell Antigen Receptors and Synergism With Chemokine Receptor CXCR4

Author(s): Palash C. Maity, Moumita Datta, Antonella Nicolò, Hassan Jumaa
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
DOI: 10.3389/fimmu.2018.02988

IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia

Author(s): Ameera Alsadeq, Lennart Lenk, Anila Vadakumchery, Antony Cousins, Christian Vokuhl, Ahmad Khadour, Fotini Vogiatzi, Felix Seyfried, Lueder-Hinrich Meyer, Gunnar Cario, Elias Hobeika, Klaus-Michael Debatin, Christina Halsey, Martin Schrappe, Denis M. Schewe, Hassan Jumaa
Published in: Blood, Issue 132/15, 2018, Page(s) 1614-1617, ISSN 0006-4971
DOI: 10.1182/blood-2018-04-844209

PI3K-Mediated Blimp-1 Activation Controls B Cell Selection and Homeostasis

Author(s): Corinna S. Setz, Eva Hug, Ahmad Khadour, Hend Abdelrasoul, Mayas Bilal, Elias Hobeika, Hassan Jumaa
Published in: Cell Reports, Issue 24/2, 2018, Page(s) 391-405, ISSN 2211-1247
DOI: 10.1016/j.celrep.2018.06.035

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope

Author(s): Katharina Imkeller, Stephen W. Scally, Alexandre Bosch, Gemma Pidelaserra Martí, Giulia Costa, Gianna Triller, Rajagopal Murugan, Valerio Renna, Hassan Jumaa, Peter G. Kremsner, B. Kim Lee Sim, Stephen L. Hoffman, Benjamin Mordmüller, Elena A. Levashina, Jean-Philippe Julien, Hedda Wardemann
Published in: Science, Issue 360/6395, 2018, Page(s) 1358-1362, ISSN 0036-8075
DOI: 10.1126/science.aar5304

B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies

Author(s): Gang Xiao, Lai N. Chan, Lars Klemm, Daniel Braas, Zhengshan Chen, Huimin Geng, Qiuyi Chen Zhang, Ali Aghajanirefah, Kadriye Nehir Cosgun, Teresa Sadras, Jaewoong Lee, Tamara Mirzapoiazova, Ravi Salgia, Thomas Ernst, Andreas Hochhaus, Hassan Jumaa, Xiaoyan Jiang, David M. Weinstock, Thomas G. Graeber, Markus Müschen
Published in: Cell, Issue 173/2, 2018, Page(s) 470-484.e18, ISSN 0092-8674
DOI: 10.1016/j.cell.2018.02.048

Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia

Author(s): Claudia Minici, Maria Gounari, Rudolf Übelhart, Lydia Scarfò, Marcus Dühren-von Minden, Dunja Schneider, Alpaslan Tasdogan, Alabbas Alkhatib, Andreas Agathangelidis, Stavroula Ntoufa, Nicholas Chiorazzi, Hassan Jumaa, Kostas Stamatopoulos, Paolo Ghia, Massimo Degano
Published in: Nature Communications, Issue 8, 2017, Page(s) 15746, ISSN 2041-1723
DOI: 10.1038/ncomms15746

Pten controls B‐cell responsiveness and germinal center reaction by regulating the expression of IgD BCR

Author(s): Corinna S Setz, Ahmad Khadour, Valerio Renna, Joseena Iype, Eva Gentner, Xiaocui He, Moumita Datta, Marc Young, Lars Nitschke, Jürgen Wienands, Palash C Maity, Michael Reth, Hassan Jumaa
Published in: The EMBO Journal, 2019, Page(s) e100249, ISSN 0261-4189
DOI: 10.15252/embj.2018100249