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Signal Integration by Gene Regulatory Landscapes

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The Gremlin1 cis-Regulatory Landscape: A Paradigm to Study Enhancer Cooperation in Regulation of Transcription Dynamics

Author(s): Laurène Ramos Martins
Published in: 2020
Publisher: University of Basel

cis-Regulation of Gremlin1 Expression during MouseLimb Bud Development and its Diversification during Vertebrate Evolution

Author(s): Jonas Malkmus
Published in: 2022
Publisher: University of Basel

Dynamic and self-regulatory interactions among gene regulatory networks control vertebrate limb bud morphogenesis (review)

Author(s): Aimee Zuniga, Rolf Zeller
Published in: Current Topics in Developmental Biology, 139, 2020, Page(s) 61-87, ISSN 0070-2153
Publisher: Academic Press
DOI: 10.1016/bs.ctdb.2020.02.005

HOX13-dependent chromatin accessibility modulates the target repertoires of the HOX factors

Author(s): Ines Desanlis; Yacine Kherdjemil; Alexandre Mayran; Bouklouch Y; Claudia Gentile; Rushikesh Sheth; Rolf Zeller; Jacques Drouin; Marie Kmita; Marie Kmita
Published in: Nature Communications, 11: 2491, 2020, Page(s) 1-10, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1101/789875

SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning

Author(s): Julie Gamart, Iros Barozzi, Frédéric Laurent, Robert Reinhardt, Laurene Ramos Martins, Thomas Oberholzer, Axel Visel, Rolf Zeller, Aimée Zuniga
Published in: Development, 148, 2021, Page(s) 1-24 (online, ISSN 1477-9129
Publisher: The Company of Biologists
DOI: 10.1242/dev.200182

Conserved and species-specific chromatin remodeling and regulatory dynamics during mouse and chicken limb bud development

Author(s): Shalu Jhanwar, Jonas Malkmus, Jens Stolte, Olga Romashkina, Aimée Zuniga, Rolf Zeller
Published in: Nature Communications, 12:5685, 2021, Page(s) 1-17 (online), ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-25935-3

Molecular signatures identify immature mesenchymal progenitors in early mouse limb buds that respond differentially to morphogen signaling

Author(s): Robert Reinhardt, Fabiana Gullotta, Gretel Nusspaumer, Erkan Ünal, Robert Ivanek, Aimée Zuniga, Rolf Zeller
Published in: Development, 146/10, 2019, Page(s) dev173328, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.173328

Gene Regulatory and Expression Differences between Mouse and Pig Limb Buds Provide Insights into the Evolutionary Emergence of Artiodactyl Traits

Author(s): Virginie Tissières, Florian Geier, Barbara Kessler, Eckhard Wolf, Rolf Zeller, Javier Lopez-Rios
Published in: Cell Reports, 31/1, 2020, Page(s) 107490, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.03.054

Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity

Author(s): Jonas Malkmus, Laurène Ramos Martins, Shalu Jhanwar, Bonnie Kircher, Victorio Palacio, Rushikesh Sheth, Francisca Leal, Amandine Duchesne, Javier Lopez-Rios, Kevin A. Peterson, Robert Reinhardt, Koh Onimaru, Martin J. Cohn, Aimée Zuniga, Rolf Zeller
Published in: Nature Communications, 12:5557, 2021, Page(s) 1-17 (online), ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-25810-1