Mapping metabolic regulators at a genome-scale to switch bacteria from growth to overproduction of chemicals

Publications

Peer reviewed articles (4)

Allosteric Feedback Inhibition Enables Robust Amino Acid Biosynthesis in E. coli by Enforcing Enzyme Overabundance

Author(s): Timur Sander, Niklas Farke, Christoph Diehl, Michelle Kuntz, Timo Glatter, Hannes Link
Published in: Cell Systems, Issue 8/1, 2019, Page(s) 66-75.e8, ISSN 2405-4712
DOI: 10.1016/j.cels.2018.12.005

Broadening the Scope of Enforced ATP Wasting as a Tool for Metabolic Engineering in Escherichia coli

Author(s): Simon Boecker, Ahmed Zahoor, Thorben Schramm, Hannes Link, Steffen Klamt
Published in: Biotechnology Journal, 2019, Page(s) 1800438, ISSN 1860-6768
DOI: 10.1002/biot.201800438

Systematic identification of metabolites controlling gene expression in E. coli

Author(s): Martin Lempp, Niklas Farke, Michelle Kuntz, Sven Andreas Freibert, Roland Lill, Hannes Link
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-12474-1

High-throughput enrichment of temperature-sensitive argininosuccinate synthetase for two-stage citrulline production in E. coli

Author(s): Thorben Schramm, Martin Lempp, Dominik Beuter, Silvia González Sierra, Timo Glatter, Hannes Link
Published in: Metabolic Engineering, Issue 60, 2020, Page(s) 14-24, ISSN 1096-7176
DOI: 10.1016/j.ymben.2020.03.004