MicroRobotic toolkit to deliver spatiotemporally resolved physicochemical signals and control cell sociology

Project Information

ROBOCHIP

Grant agreement ID: 714609

DOI 10.3030/714609

Project closed

EC signature date 17 October 2016

Start date 1 March 2017

End date 31 August 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 748 773,00

EU contribution € 1 748 773,00

Coordinated by

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Switzerland

Publications

Peer reviewed articles (20)

Engineered Extracellular Matrices with Integrated Wireless Microactuators to Study Mechanobiology

Author(s): Fazil E. Uslu, Christopher D. Davidson, Erik Mailand, Nikolaos Bouklas, Brendon M. Baker, Mahmut Selman Sakar
Published in: Advanced Materials, Issue 33/40, 2021, Page(s) 2102641, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202102641

Microengineered devices enable long-term imaging of the ventral nerve cord in behaving adult Drosophila

Author(s): Laura Hermans, Murat Kaynak, Jonas Braun, Victor Lobato Ríos, Chin-Lin Chen, Adam Friedberg, Semih Günel, Florian Aymanns, Mahmut Selman Sakar, Pavan Ramdya
Published in: Nature Communications, Issue 20411723, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-32571-y

Dynamics of entrapped microbubbles with multiple openings

Author(s): Amit Dolev; Murat Kaynak; Mahmut Selman Sakar
Published in: Physics of Fluids, Issue 10706631, 2022, Page(s) 012012, ISSN 1070-6631
Publisher: American Institute of Physics
DOI: 10.1063/5.0075876

Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy

Author(s): Kewen Lei, Armand Kurum, Murat Kaynak, Lucia Bonati, Yulong Han, Veronika Cencen, Min Gao, Yu-Qing Xie, Yugang Guo, Mélanie T. M. Hannebelle, Yangping Wu, Guanyu Zhou, Ming Guo, Georg E. Fantner, Mahmut Selman Sakar, Li Tang
Published in: Nature Biomedical Engineering, Issue 2157846X, 2021, ISSN 2157-846X
Publisher: Nature
DOI: 10.1038/s41551-021-00826-6

Tissue Engineering with Mechanically Induced Solid‐Fluid Transitions

Author(s): Erik Mailand, Ece Özelçi, Jaemin Kim, Matthias Rüegg, Odysseas Chaliotis, Jon Märki, Nikolaos Bouklas, Mahmut Selman Sakar
Published in: Advanced Materials, 2021, Page(s) 2106149, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202106149

Flow driven robotic navigation of microengineered endovascular probes

Author(s): Lucio Pancaldi, Pietro Dirix, Adele Fanelli, Augusto Martins Lima, Nikolaos Stergiopulos, Pascal John Mosimann, Diego Ghezzi, Mahmut Selman Sakar
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-20195-z

Addressable Acoustic Actuation of 3D Printed Soft Robotic Microsystems

Author(s): Murat Kaynak, Pietro Dirix, Mahmut Selman Sakar
Published in: Advanced Science, Issue 7/20, 2020, Page(s) 2001120, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202001120

Remotely Controlled Colloidal Assembly of Soft Microrobotic Artificial Muscle

Author(s): Raquel Parreira, Ece Özelçi, Mahmut Selman Sakar
Published in: Advanced Intelligent Systems, Issue 2/7, 2020, Page(s) 2000062, ISSN 2640-4567
Publisher: Wiley
DOI: 10.1002/aisy.202000062

Investigating Tissue Mechanics in vitro Using Untethered Soft Robotic Microdevices

Author(s): Raquel Parreira, Ece Özelçi, Mahmut Selman Sakar
Published in: Frontiers in Robotics and AI, Issue 8, 2021, ISSN 2296-9144
Publisher: Frontiers
DOI: 10.3389/frobt.2021.649765

On‐Board Mechanical Control Systems for Untethered Microrobots

Author(s): Amit Dolev, Murat Kaynak, Mahmut Selman Sakar
Published in: Advanced Intelligent Systems, Issue 3/10, 2021, Page(s) 2000233, ISSN 2640-4567
Publisher: Wiley
DOI: 10.1002/aisy.202000233

BAF restricts cGAS on nuclear DNA to prevent innate immune activation

Author(s): Baptiste Guey, Marilena Wischnewski, Alexiane Decout, Kristina Makasheva, Murat Kaynak, Mahmut S. Sakar, Beat Fierz, Andrea Ablasser
Published in: Science, Issue 369/6505, 2020, Page(s) 823-828, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aaw6421

3D Printed Acoustically Programmable Soft Microactuators

Author(s): Murat Kaynak, Amit Dolev, Mahmut Selman Sakar
Published in: Soft Robotics, Issue 21695172, 2022, ISSN 2169-5172
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/soro.2021.0193

A model for cellular mechanotransduction and contractility at finite strain

Author(s): N. Bouklas, M. S. Sakar, W. A. Curtin
Published in: ZAMM - Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik, Issue 98/10, 2018, Page(s) 1754-1770, ISSN 0044-2267
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/zamm.201700368

Adaptive locomotion of artificial microswimmers

Author(s): H.-W. Huang, F. E. Uslu, P. Katsamba, E. Lauga, M. S. Sakar, B. J. Nelson
Published in: Science Advances, Issue 5/1, 2019, Page(s) eaau1532, ISSN 2375-2548
Publisher: Science Advances
DOI: 10.1126/sciadv.aau1532

Surface and Bulk Stresses Drive Morphological Changes in Fibrous Microtissues

Author(s): Erik Mailand, Bin Li, Jeroen Eyckmans, Nikolaos Bouklas, Mahmut Selman Sakar
Published in: Biophysical Journal, Issue 117/5, 2019, Page(s) 975-986, ISSN 0006-3495
Publisher: Biophysical Society
DOI: 10.1016/j.bpj.2019.07.041

Modular soft robotic microdevices for dexterous biomanipulation

Author(s): Berna Özkale, Raquel Parreira, Ahmet Bekdemir, Lucio Pancaldi, Ece Özelçi, Claire Amadio, Murat Kaynak, Francesco Stellacci, David J. Mooney, Mahmut Selman Sakar
Published in: Lab on a Chip, Issue 19/5, 2019, Page(s) 778-788, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8lc01200h

Universal Soft Robotic Microgripper

Author(s): Haiyan Jia, Erik Mailand, Jiangtao Zhou, Zhangjun Huang, Giovanni Dietler, John M. Kolinski, Xinling Wang, Mahmut Selman Sakar
Published in: Small, Issue 15/4, 2019, Page(s) 1803870, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201803870

Deconstructing body axis morphogenesis in zebrafish embryos using robot-assisted tissue micromanipulation

Author(s): Ece Ozelci, Erik Mailand, Matthias Ruegg, Andrew Oates, Mahmut Selman Sakar
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-35632-4

A model for 3D deformation and reconstruction of contractile microtissues

Author(s): Jaemin Kim, Erik Mailand, Ida Ang, Mahmut Selman Sakar, Nikolaos Bouklas
Published in: Soft Matter, 2021, ISSN 1744-683X
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sm01182g

Locomotion of Sensor‐Integrated Soft Robotic Devices Inside Sub‐Millimeter Arteries with Impaired Flow Conditions

Author(s): Lucio Pancaldi; Lorenzo Noseda; Amit Dolev; Adele Fanelli; Diego Ghezzi; Andrew J. Petruska; Mahmut Selman Sakar
Published in: Advanced Intelligent Systems, Issue 26404567, 2022, Page(s) 2100247, ISSN 2640-4567
Publisher: Wiley-VCH
DOI: 10.1002/aisy.202100247

Conference proceedings (1)

Compound micromachines powered by acoustic streaming

Author(s): Murat Kaynak, Furkan Ayhan, Mahmut Selman Sakar
Published in: 2019 International Conference on Robotics and Automation (ICRA), 2019, Page(s) 225-230, ISBN 978-1-5386-6027-0
Publisher: IEEE
DOI: 10.1109/icra.2019.8793481

Non-peer reviewed articles (1)

Engineering Control over 3D Morphogenesis by Tissue Origami

Author(s): Mahmut Selman Sakar, Brendon M. Baker
Published in: Developmental Cell, Issue 44/2, 2018, Page(s) 131-132, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2018.01.005