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The importance of transcriptional coordination during development


Imaging translation dynamics in live embryos reveals spatial heterogeneities

Author(s): Jeremy Dufourt, Maelle Bellec, Antonio Trullo, Matthieu Dejean, Sylvain De Rossi, Cyril Favard, Mounia Lagha
Published in: Science, 372/6544, 2021, Page(s) 840-844, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abc3483

Quantitative imaging of transcription in living Drosophila embryos reveals the impact of core promoter motifs on promoter state dynamics

Author(s): Virginia L. Pimmett, Matthieu Dejean, Carola Fernandez, Antonio Trullo, Edouard Bertrand, Ovidiu Radulescu, Mounia Lagha
Published in: Nature Communications, 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24461-6

Cis-regulatory chromatin loops arise before TADs and gene activation, and are independent of cell fate during early Drosophila development

Author(s): Sergio Martin Espinola, Markus Götz, Maelle Bellec, Olivier Messina, Jean-Bernard Fiche, Christophe Houbron, Matthieu Dejean, Ingolf Reim, Andrés M. Cardozo Gizzi, Mounia Lagha, Marcelo Nollmann
Published in: Nature Genetics, 53/4, 2021, Page(s) 477-486, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-021-00816-z

Microscopy-Based Chromosome Conformation Capture Enables Simultaneous Visualization of Genome Organization and Transcription in Intact Organisms

Author(s): Andrés M. Cardozo Gizzi, Diego I. Cattoni, Jean-Bernard Fiche, Sergio M. Espinola, Julian Gurgo, Olivier Messina, Christophe Houbron, Yuki Ogiyama, Giorgio L. Papadopoulos, Giacomo Cavalli, Mounia Lagha, Marcelo Nollmann
Published in: Molecular Cell, 74/1, 2019, Page(s) 212-222.e5, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.01.011

Remembering the past: Mitotic bookmarking in a developing embryo

Author(s): Maelle Bellec, Ovidiu Radulescu, Mounia Lagha
Published in: Current Opinion in Systems Biology, 11, 2018, Page(s) 41-49, ISSN 2452-3100
Publisher: Elsevier
DOI: 10.1016/j.coisb.2018.08.003

A Growing Toolbox to Image Gene Expression in Single Cells: Sensitive Approaches for Demanding Challenges

Author(s): Xavier Pichon, Mounia Lagha, Florian Mueller, Edouard Bertrand
Published in: Molecular Cell, 71/3, 2018, Page(s) 468-480, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2018.07.022

MitoTrack, a user-friendly semi-automatic software for lineage tracking in living embryos

Author(s): A Trullo, J Dufourt, M Lagha
Published in: Bioinformatics, 2019, ISSN 1367-4803
Publisher: Oxford University Press
DOI: 10.1093/bioinformatics/btz717

Tyramine induces dynamic RNP granule remodeling and translation activation in the Drosophila brain

Author(s): Nadia Formicola, Marjorie Heim, Jérémy Dufourt, Anne-Sophie Lancelot, Akira Nakamura, Mounia Lagha, Florence Besse
Published in: eLife, 10, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.65742

Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs

Author(s): Jeremy Dufourt, Antonio Trullo, Jennifer Hunter, Carola Fernandez, Jorge Lazaro, Matthieu Dejean, Lucas Morales, Saida Nait-Amer, Katharine N. Schulz, Melissa M. Harrison, Cyril Favard, Ovidiu Radulescu, Mounia Lagha
Published in: Nature Communications, 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-07613-z