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Thoroughly Optimised Production Chassis for Advanced Pharmaceutical Ingredients

Deliverables

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Project manager appointed

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Publications

Development and validation of an updated computational model of Streptomyces coelicolor primary and secondary metabolism

Author(s): Adam Amara, Eriko Takano, Rainer Breitling
Published in: BMC Genomics, Issue 19/1, 2018, ISSN 1471-2164
DOI: 10.1186/s12864-018-4905-5

Computational identification of co-evolving multi-gene modules in microbial biosynthetic gene clusters

Author(s): Francesco Del Carratore, Konrad Zych, Matthew Cummings, Eriko Takano, Marnix H. Medema, Rainer Breitling
Published in: Communications Biology, Issue 2/1, 2019, ISSN 2399-3642
DOI: 10.1038/s42003-019-0333-6

Integrated Probabilistic Annotation: A Bayesian-Based Annotation Method for Metabolomic Profiles Integrating Biochemical Connections, Isotope Patterns, and Adduct Relationships

Author(s): Francesco Del Carratore, Kamila Schmidt, Maria Vinaixa, Katherine A. Hollywood, Caitlin Greenland-Bews, Eriko Takano, Simon Rogers, Rainer Breitling
Published in: Analytical Chemistry, Issue 91/20, 2019, Page(s) 12799-12807, ISSN 0003-2700
DOI: 10.1021/acs.analchem.9b02354

Antibiotic export: transporters involved in the final step of natural product production

Author(s): Emmanuele Severi, Gavin H. Thomas
Published in: Microbiology, Issue 165/8, 2019, Page(s) 805-818, ISSN 1350-0872
DOI: 10.1099/mic.0.000794