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Functional characterisation of mitochondrial metabolic adaptations to innate sensing in dendritic cell subsets

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Publications

Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen

Author(s): Stefanie K. Wculek, Joaquín Amores-Iniesta, Ruth Conde-Garrosa, Sofía C. Khouili, Ignacio Melero, David Sancho
Published in: Journal for ImmunoTherapy of Cancer, Issue 7/1, 2019, Page(s) 100, ISSN 2051-1426
DOI: 10.1186/s40425-019-0565-5

Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation

Author(s): Carlos del Fresno, Salvador Iborra, Paula Saz-Leal, María Martínez-López, David Sancho
Published in: Frontiers in Immunology, Issue 9, 2018, Page(s) 804, ISSN 1664-3224
DOI: 10.3389/fimmu.2018.00804

Leishmania Hijacks Myeloid Cells for Immune Escape

Author(s): María Martínez-López, Manuel Soto, Salvador Iborra, David Sancho
Published in: Frontiers in Microbiology, Issue 9, 2018, Page(s) 883, ISSN 1664-302X
DOI: 10.3389/fmicb.2018.00883

Genealogy, Dendritic Cell Priming, and Differentiation of Tissue-Resident Memory CD8+ T Cells

Author(s): Michel Enamorado, Sofía C. Khouili, Salvador Iborra, David Sancho
Published in: Frontiers in Immunology, Issue 9, 2018, Page(s) 1751, ISSN 1664-3224
DOI: 10.3389/fimmu.2018.01751

Dectin-1/2–induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses

Author(s): Maria M. M. Kaisar, Manuel Ritter, Carlos del Fresno, Hulda S. Jónasdóttir, Alwin J. van der Ham, Leonard R. Pelgrom, Gabriele Schramm, Laura E. Layland, David Sancho, Clarissa Prazeres da Costa, Martin Giera, Maria Yazdanbakhsh, Bart Everts
Published in: PLOS Biology, Issue 16/4, 2018, Page(s) e2005504, ISSN 1545-7885
DOI: 10.1371/journal.pbio.2005504

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis

Author(s): Tamara Girbl, Tchern Lenn, Lorena Perez, Loïc Rolas, Anna Barkaway, Aude Thiriot, Carlos del Fresno, Eleanor Lynam, Elin Hub, Marcus Thelen, Gerard Graham, Ronen Alon, David Sancho, Ulrich H. von Andrian, Mathieu-Benoit Voisin, Antal Rot, Sussan Nourshargh
Published in: Immunity, Issue 49/6, 2018, Page(s) 1062-1076.e6, ISSN 1074-7613
DOI: 10.1016/j.immuni.2018.09.018

Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming

Author(s): Dieke van Dinther, Henrike Veninga, Salvador Iborra, Ellen G.F. Borg, Leoni Hoogterp, Katarzyna Olesek, Marieke R. Beijer, Sjoerd T.T. Schetters, Hakan Kalay, Juan J. Garcia-Vallejo, Kees L. Franken, Lamin B. Cham, Karl S. Lang, Yvette van Kooyk, David Sancho, Paul R. Crocker, Joke M.M. den Haan
Published in: Cell Reports, Issue 22/6, 2018, Page(s) 1484-1495, ISSN 2211-1247
DOI: 10.1016/j.celrep.2018.01.021

Von Hippel-Lindau Protein Is Required for Optimal Alveolar Macrophage Terminal Differentiation, Self-Renewal, and Function

Author(s): Helena M. Izquierdo, Paola Brandi, Manuel-José Gómez, Ruth Conde-Garrosa, Elena Priego, Michel Enamorado, Sarai Martínez-Cano, Iria Sánchez, Laura Conejero, Daniel Jimenez-Carretero, Silvia Martín-Puig, Martin Guilliams, David Sancho
Published in: Cell Reports, Issue 24/7, 2018, Page(s) 1738-1746, ISSN 2211-1247
DOI: 10.1016/j.celrep.2018.07.034

DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment

Author(s): Carlos del Fresno, Paula Saz-Leal, Michel Enamorado, Stefanie K. Wculek, Sarai Martínez-Cano, Noelia Blanco-Menéndez, Oliver Schulz, Mattia Gallizioli, Francesc Miró-Mur, Eva Cano, Anna Planas, David Sancho
Published in: Science, Issue 362/6412, 2018, Page(s) 351-356, ISSN 0036-8075
DOI: 10.1126/science.aan8423

Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection

Author(s): Paula Saz-Leal, Carlos del Fresno, Paola Brandi, Sarai Martínez-Cano, Otto M. Dungan, John D. Chisholm, William G. Kerr, David Sancho
Published in: Cell Reports, Issue 25/5, 2018, Page(s) 1118-1126, ISSN 2211-1247
DOI: 10.1016/j.celrep.2018.09.092

Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity

Author(s): María Martínez-López, Salvador Iborra, Ruth Conde-Garrosa, Annalaura Mastrangelo, Camille Danne, Elizabeth R. Mann, Delyth M. Reid, Valérie Gaboriau-Routhiau, Maria Chaparro, María P. Lorenzo, Lara Minnerup, Paula Saz-Leal, Emma Slack, Benjamin Kemp, Javier P. Gisbert, Andrzej Dzionek, Matthew J. Robinson, Francisco J. Rupérez, Nadine Cerf-Bensussan, Gordon D. Brown, David Bernardo, Salomé
Published in: Immunity, Issue 50/2, 2019, Page(s) 446-461.e9, ISSN 1074-7613
DOI: 10.1016/j.immuni.2018.12.020

Metabolic Control of Dendritic Cell Functions: Digesting Information

Author(s): Stefanie K. Wculek, Sofía C. Khouili, Elena Priego, Ignacio Heras-Murillo, David Sancho
Published in: Frontiers in Immunology, Issue 10, 2019, Page(s) 775, ISSN 1664-3224
DOI: 10.3389/fimmu.2019.00775

cDC1s: New Orchestrators of Tissue Innate Immunity

Author(s): Carlos del Fresno, David Sancho
Published in: Trends in Immunology, Issue 40/7, 2019, Page(s) 559-561, ISSN 1471-4906
DOI: 10.1016/j.it.2019.05.002

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

Author(s): José M. Adrover, Carlos del Fresno, Georgiana Crainiciuc, Maria Isabel Cuartero, María Casanova-Acebes, Linnea A. Weiss, Hector Huerga-Encabo, Carlos Silvestre-Roig, Jan Rossaint, Itziar Cossío, Ana V. Lechuga-Vieco, Jaime García-Prieto, Mónica Gómez-Parrizas, Juan A. Quintana, Ivan Ballesteros, Sandra Martin-Salamanca, Alejandra Aroca-Crevillen, Shu Zhen Chong, Maximilien Evrard, Karl Balab
Published in: Immunity, Issue 50/2, 2019, Page(s) 390-402.e10, ISSN 1074-7613
DOI: 10.1016/j.immuni.2019.01.002