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Personalised Medicine in Diabetic Chronic Disease Management

Deliverables

Ethics Report for each call

The Ethics Reports after each call should contain at least the following information: - A short description on how the ethics procedure in place (as described in Annex I of the Grant Agreement) was followed and the adaptations made if relevant. This part should also include a description of the role and composition of the ethics committee if such a committee was involved. - An overview table based on the following structure (only for the successful fellows): name of the researcher; the title of research project with ethical issues; the ethics area(s) concerned; conditions to be fulfilled for funding and ethics requirements to be monitored during implementation; follow-up during the implementation. Only those research projects having ethics issues need to be detailed in this table (M18).

Report/s on dissemination activities

Report on dissemination activities (containing at least the following information): i) dates of Call Publication and places where is was published (supporting documents required).

Inform for each call the Project Officer

Inform for each call the Project Officer by sending the link to the Euraxess website where the call has been published (M2). This delivarble shall provide the PO with deatils of the publication of the call on the Euraxess website. Note: data on Euraxess shall be prived any time between M1 and M2.

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Publications

TEMPO‐Mediated Electrochemical N‐demethylation of Opiate Alkaloids

Author(s): Ali Alipour Najmi, M. Faizan Bhat, Rainer Bischoff, Gerrit J. Poelarends, Hjalmar P. Permentier
Published in: ChemElectroChem, Issue 8/13, 2021, Page(s) 2590-2596, ISSN 2196-0216
DOI: 10.1002/celc.202100784

HDL particle subspecies and their association with incident type 2 diabetes: the PREVEND study

Author(s): Sara Sokooti, Jose L Flores-Guerrero, Lyanne M Kieneker, Hiddo J L Heerspink, Margery A Connelly, Stephan J L Bakker, Robin P F Dullaart
Published in: The Journal of Clinical Endocrinology & Metabolism, 2021, ISSN 0021-972X
DOI: 10.1210/clinem/dgab075

Older Age, Polypharmacy, and Low Systolic Blood Pressure Are Associated With More Hypotension-Related Adverse Events in Patients With Type 2 Diabetes Treated With Antihypertensives

Author(s): Martina Ambrož, Sieta T. de Vries, Klaas Hoogenberg and Petra Denig
Published in: Frontiers in Pharmacology, Issue 12, 2021, ISSN 1663-9812
DOI: 10.3389/fphar.2021.728911

Plasma creatine concentration is associated with incident hypertension in a cohort enriched for the presence of high urinary albumin concentration

Author(s): Adrian Post, Daan Kremer, J. Casper Swarte, Sara Sokooti, Fabian A. Vogelpohl, Dion Groothof, Ido.P. Kema, Erwin Garcia, Margery A. Connelly, Theo Wallimann, Robin P.F. Dullaart, Casper F.M. Franssen, Stephan J.L. Bakker
Published in: Journal of Hypertension, Issue Publish Ahead of Print, 2021, ISSN 0263-6352
DOI: 10.1097/hjh.0000000000002996

Separate and combined effects of individual and neighbourhood socio-economic disadvantage on health-related lifestyle risk factors: a multilevel analysis

Author(s): Yinjie Zhu, Ming-Jie Duan, Ineke J Riphagen, Isidor Minovic, Jochen O Mierau, Juan-Jesus Carrero, Stephan J L Bakker, Gerjan J Navis, Louise H Dekker
Published in: International Journal of Epidemiology, 2021, ISSN 0300-5771
DOI: 10.1093/ije/dyab079

Plasma C-Peptide and Risk of Developing Type 2 Diabetes in the General Population

Author(s): Sokooti S, Kieneker LM, de Borst MH, Muller Kobold A, Kootstra-Ros JE, Gloerich J, van Gool AJ, Lambers Heerspink HJ, Gansevoort RT, Dullaart RPF, Bakker SJL
Published in: Journal of Clinical Medicine, 2020, ISSN 2077-0383
DOI: 10.3390/jcm9093001

Changes in blood pressure thresholds for initiating antihypertensive medication in patients with diabetes: a repeated cross-sectional study focusing on the impact of age and frailty

Author(s): Martina Ambrož, Sieta T de Vries, Grigory Sidorenkov, Klaas Hoogenberg, Petra Denig
Published in: BMJ Open, Issue 10/9, 2020, Page(s) e037694, ISSN 2044-6055
DOI: 10.1136/bmjopen-2020-037694

Epigenetic regulation in macrophage migration inhibitory factor (MIF)-mediated signaling in cancer and inflammation

Author(s): Angelina Osipyan, Deng Chen, Frank J. Dekker
Published in: Drug Discovery Today, 2021, ISSN 1359-6446
DOI: 10.1016/j.drudis.2021.03.012

Sex Differences in Lipid Profile across the Life Span in Patients with Type 2 Diabetes: A Primary Care-Based Study

Author(s): Martina Ambrož, Sieta T. de Vries, Priya Vart, Robin P. F. Dullaart, Jeanine Roeters van Lennep, Petra Denig, Klaas Hoogenberg
Published in: Journal of Clinical Medicine, Issue 10/8, 2021, Page(s) 1775, ISSN 2077-0383
DOI: 10.3390/jcm10081775

Precision medicine approaches for diabetic kidney disease: opportunities and challenges

Author(s): Sok Cin Tye, Petra Denig, Hiddo J L Heerspink
Published in: Nephrology Dialysis Transplantation, Issue 36/Supplement_2, 2021, Page(s) 3-9, ISSN 0931-0509
DOI: 10.1093/ndt/gfab045

Association between socioeconomic status and self-reported, tested and diagnosed COVID-19 status during the first wave in the Northern Netherlands: a general population-based cohort from 49 474 adults

Author(s): Yinjie Zhu, Ming-Jie Duan, Hermien H. Dijk, Roel D. Freriks, Louise H. Dekker, Jochen O. Mierau
Published in: BMJ Open, Issue 11/3, 2021, Page(s) e048020, ISSN 2044-6055
DOI: 10.1136/bmjopen-2020-048020

A novel drug response score more accurately predicts renoprotective drug effects than existing renal risk scores

Author(s): Nienke M. A. Idzerda, Sok Cin Tye, Dick de Zeeuw, Hiddo J. L. Heerspink
Published in: Therapeutic Advances in Endocrinology and Metabolism, Issue 12, 2021, Page(s) 204201882097419, ISSN 2042-0188
DOI: 10.1177/2042018820974191

Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid

Author(s): Jan Freark de Boer, Hilde D. de Vries, Anna Palmiotti, Rumei Li, Marwah Doestzada, Joanne A. Hoogerland, Jingyuan Fu, Anouk M. La Rose, Marit Westerterp, Niels L. Mulder, Milaine V. Hovingh, Martijn Koehorst, Niels J. Kloosterhuis, Justina C. Wolters, Vincent W. Bloks, Joel T. Haas, David Dombrowicz, Bart Staels, Bart van de Sluis, Folkert Kuipers
Published in: Cellular and Molecular Gastroenterology and Hepatology, 2020, ISSN 2352-345X
DOI: 10.1016/j.jcmgh.2020.12.004

Different circulating biomarkers in women and men with paroxysmal atrial fibrillation: results from the AF-RISK and RACE V studies

Author(s): Ruben R De With, Vicente Artola Arita, Bao-Oanh Nguyen, Dominik Linz, Hugo Ten Cate, Henri Spronk, Ulrich Schotten, Anton Jan van Zonneveld, Ömer Erküner, M Agustina Bayón, Anders S Schmidt, Justin G L M Luermans, Harry J G M Crijns, Isabelle C Van Gelder, Michiel Rienstra
Published in: EP Europace, 2021, ISSN 1099-5129
DOI: 10.1093/europace/euab179

Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles

Author(s): Qian Wang, Angelina Osipyan, Markella Konstantinidou, Roberto Butera, Kumchok C. Mgimpatsang, Svitlana V. Shishkina, Alexander Dömling
Published in: The Journal of Organic Chemistry, 2019, ISSN 0022-3263
DOI: 10.1021/acs.joc.9b01258

Differences in medication beliefs between pregnant women using medication, or not, for chronic diseases: a cross-sectional, multinational, web-based study

Author(s): Sonia Roldan Munoz, Angela Lupattelli, Sieta T de Vries, Peter G M Mol, Hedvig Nordeng
Published in: BMJ Open, Issue 10/2, 2020, Page(s) e034529, ISSN 2044-6055
DOI: 10.1136/bmjopen-2019-034529

Automated, Accelerated Nanoscale Synthesis of Iminopyrrolidines

Author(s): Angelina Osipyan, Shabnam Shaabani, Robert Warmerdam, Svitlana V. Shishkina, Harry Boltz, Alexander Dömling
Published in: Angewandte Chemie International Edition, 2020, ISSN 1433-7851
DOI: 10.1002/anie.202000887

High-Density Lipoprotein Particles and Their Relationship to Posttransplantation Diabetes Mellitus in Renal Transplant Recipients

Author(s): Sara Sokooti, Tamas Szili-Torok, Jose L. Flores-Guerrero, Maryse C. J. Osté, António W. Gomes-Neto, Jenny E. Kootstra-Ros, Hiddo J.L. Heerspink, Margery A. Connelly, Stephan J. L. Bakker, Robin P. F. Dullaart
Published in: Biomolecules, Issue 10/3, 2020, Page(s) 481, ISSN 2218-273X
DOI: 10.3390/biom10030481

A personalised screening strategy for diabetic retinopathy: a cost-effectiveness perspective

Author(s): Sajad Emamipour, Amber A. W. A. van der Heijden, Giel Nijpels, Petra Elders, Joline W. J. Beulens, Maarten J. Postma, Job F. M. van Boven, Talitha L. Feenstra
Published in: Diabetologia, 2020, ISSN 0012-186X
DOI: 10.1007/s00125-020-05239-9

Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid

Author(s): Jan Freark de Boer, Hilde D. de Vries, Anna Palmiotti, Rumei Li, Marwah Doestzada, Joanne A. Hoogerland, Jingyuan Fu, Anouk M. La Rose, Marit Westerterp, Niels L. Mulder, Milaine V. Hovingh, Martijn Koehorst, Niels J. Kloosterhuis, Justina C. Wolters, Vincent W. Bloks, Joel T. Haas, David Dombrowicz, Bart Staels, Bart van de Sluis, Folkert Kuipers
Published in: Cellular and Molecular Gastroenterology and Hepatology, Issue 11/4, 2021, Page(s) 1045-1069, ISSN 2352-345X
DOI: 10.1016/j.jcmgh.2020.12.004•

The genetics of asthma and the promise of genomics-guided drug target discovery

Author(s): Zaid W El-Husseini, Reinoud Gosens, Frank Dekker, Gerard H Koppelman
Published in: The Lancet Respiratory Medicine, 2020, ISSN 2213-2600
DOI: 10.1016/s2213-2600(20)30363-5

Trends in HbA1c thresholds for initiation of hypoglycemic agents: Impact of changed recommendations for older and frail patients

Author(s): Martina Ambrož, Sieta T. de Vries, Klaas Hoogenberg, Petra Denig
Published in: Pharmacoepidemiology and Drug Safety, 2020, ISSN 1099-1557
DOI: 10.1002/pds.5129

Differences in Importance Attached to Drug Effects Between Patients With Type 2 Diabetes From the Netherlands and Turkey: A Preference Study

Author(s): Sonia Roldan Munoz, Douwe Postmus, Sieta T. de Vries, Arna H. Arnardottir, İlknur Dolu, Hans Hillege, Peter G. M. Mol
Published in: Frontiers in Pharmacology, Issue 11, 2021, ISSN 1663-9812
DOI: 10.3389/fphar.2020.617409

Triglyceride-rich lipoprotein and LDL particle subfractions and their association with incident type 2 diabetes: the PREVEND study

Author(s): Sara Sokooti, Jose L. Flores-Guerrero, Hiddo J. L. Heerspink, Margery A. Connelly, Stephan J. L. Bakker, Robin P. F. Dullaart
Published in: Cardiovascular Diabetology, Issue 20/1, 2021, ISSN 1475-2840
DOI: 10.1186/s12933-021-01348-w

Blood lipids-related dietary patterns derived from reduced rank regression are associated with incident type 2 diabetes

Author(s): Ming-Jie Duan, Louise H. Dekker, Juan-Jesus Carrero, Gerjan Navis
Published in: Clinical Nutrition, Issue 40/7, 2021, Page(s) 4712-4719, ISSN 0261-5614
DOI: 10.1016/j.clnu.2021.04.046