Personalised Medicine in Diabetic Chronic Disease Management

Leistungen

Research Training Portfolio This consist of where appropriate i TSPs set up for each ESR M12 ii PROMINENT specific course for all ESRs and pillarspecific course on current topics in the field M13 iii External secondments research training at Partner Organisations M60 iv PhD degree awarded to all ESRs M60

Ethics Report for each call

The Ethics Reports after each call should contain at least the following information: - A short description on how the ethics procedure in place (as described in Annex I of the Grant Agreement) was followed and the adaptations made if relevant. This part should also include a description of the role and composition of the ethics committee if such a committee was involved. - An overview table based on the following structure (only for the successful fellows): name of the researcher; the title of research project with ethical issues; the ethics area(s) concerned; conditions to be fulfilled for funding and ethics requirements to be monitored during implementation; follow-up during the implementation. Only those research projects having ethics issues need to be detailed in this table (M18).

Final Ethics Report

The Final Ethics Report should summarise the ethics procedure followed during the entire project lifecycle and focus on the adaptation made and lessons learned The report should also confirm that all required approvals authorisations were obtained and that the research was conducted in compliance with the ethical principles and applicable international EU and national law under H2020 M60

Report/s on dissemination activities

Report on dissemination activities (containing at least the following information): i) dates of Call Publication and places where is was published (supporting documents required).

Inform for each call the Project Officer

Inform for each call the Project Officer by sending the link to the Euraxess website where the call has been published (M2). This delivarble shall provide the PO with deatils of the publication of the call on the Euraxess website. Note: data on Euraxess shall be prived any time between M1 and M2.

Veröffentlichungen

Less Timely Initiation of Glucose-Lowering Medication Among Younger and Male Patients With Diabetes and Similar Initiation of Blood Pressure-Lowering Medication Across Age and Sex: Trends Between 2015 and 2020

Autoren: Martina Ambrož, Sieta T. de Vries, Klaas Hoogenberg, Petra Denig
Veröffentlicht in: Front Pharmacol, 2022, ISSN 1663-9812
Herausgeber: Frontiers Media S.A.
DOI: 10.3389/fphar.2022.883103

Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acids

Autoren: Hilde D. de Vries, Anna Palmiotti, Rumei Li, Milaine V. Hovingh, Niels L. Mulder, Martijn Koehorst, Vincent W. Bloks, Tim van Zutphen, Folkert Kuipers, Jan Freark de Boer
Veröffentlicht in: Pediatr Res, 2023, ISSN 0031-3998
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1038/s41390-022-02303-5

Personalizing the Use of a Intermittently Scanned Continuous Glucose Monitoring (isCGM) Device in Individuals With Type 1 Diabetes: A Cost-Effectiveness Perspective in the Netherlands (FLARE-NL 9)

Autoren: Sajad Emamipour, Peter R van Dijk, Henk J G Bilo, Mireille A Edens, Onno van der Galiën, Maarten J Postma, Talitha L Feenstra, Job F M van Boven
Veröffentlicht in: J Diabetes Sci Technol, 2022, ISSN 1932-2968
Herausgeber: Diabetes Technology Society
DOI: 10.1177/19322968221109841

TEMPO‐Mediated Electrochemical N‐demethylation of Opiate Alkaloids

Autoren: Ali Alipour Najmi, M. Faizan Bhat, Rainer Bischoff, Gerrit J. Poelarends, Hjalmar P. Permentier
Veröffentlicht in: ChemElectroChem, Ausgabe 8/13, 2021, Seite(n) 2590-2596, ISSN 2196-0216
Herausgeber: John Wiley and Sons Ltd
DOI: 10.1002/celc.202100784

HDL particle subspecies and their association with incident type 2 diabetes: the PREVEND study

Autoren: Sara Sokooti, Jose L Flores-Guerrero, Lyanne M Kieneker, Hiddo J L Heerspink, Margery A Connelly, Stephan J L Bakker, Robin P F Dullaart
Veröffentlicht in: The Journal of Clinical Endocrinology & Metabolism, 2021, ISSN 0021-972X
Herausgeber: The Endocrine Society
DOI: 10.1210/clinem/dgab075

Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation: Analysis of AF-RISK

Autoren: Manouk J.W. van Mourik, Vicente Artola Arita, Aurore Lyon, Joost Lumens, Ruben R. De With, Joost P. van Melle, Ulrich Schotten, Sebastiaan C.A.M. Bekkers, Harry J.G.M. Crijns, Isabelle C. Van Gelder, Michiel Rienstra, Dominik K. Linz
Veröffentlicht in: Int J Cardiol, 2022, ISSN 0167-5273
Herausgeber: Elsevier BV
DOI: 10.1016/j.ijcard.2022.05.044

Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos

Autoren: Deng Chen, Angelina Osipyan, Jeaunice Adriana, Mohammed Kader, Maxim Gureev, Catharina W. J. Knol, Marie-Cathérine Sigmund, Zhangping Xiao, Petra E. van der Wouden, Robbert H. Cool, Gerrit J. Poelarends, and Frank J. Dekker
Veröffentlicht in: J Med Chem, 2023, ISSN 0022-2623
Herausgeber: American Chemical Society
DOI: 10.1021/acs.jmedchem.3c00397

Older Age, Polypharmacy, and Low Systolic Blood Pressure Are Associated With More Hypotension-Related Adverse Events in Patients With Type 2 Diabetes Treated With Antihypertensives

Autoren: Martina Ambrož, Sieta T. de Vries, Klaas Hoogenberg and Petra Denig
Veröffentlicht in: Frontiers in Pharmacology, Ausgabe 12, 2021, ISSN 1663-9812
Herausgeber: Frontiers Media S.A.
DOI: 10.3389/fphar.2021.728911

Plasma creatine concentration is associated with incident hypertension in a cohort enriched for the presence of high urinary albumin concentration

Autoren: Adrian Post, Daan Kremer, J. Casper Swarte, Sara Sokooti, Fabian A. Vogelpohl, Dion Groothof, Ido.P. Kema, Erwin Garcia, Margery A. Connelly, Theo Wallimann, Robin P.F. Dullaart, Casper F.M. Franssen, Stephan J.L. Bakker
Veröffentlicht in: Journal of Hypertension, Ausgabe Publish Ahead of Print, 2021, ISSN 0263-6352
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000002996

The transferability and validity of a population-level simulation model for the economic evaluation of interventions in diabetes: the MICADO model

Autoren: Sajad Emamipour, Eva Pagano, Daniela Di Cuonzo, Stefan R. A. Konings, Amber A. van der Heijden, Petra Elders, Joline W. J. Beulens, Jose Leal, Talitha L. Feenstra
Veröffentlicht in: Acta Diabetol, 2022, ISSN 0940-5429
Herausgeber: Springer Verlag
DOI: 10.1007/s00592-022-01891-2

Separate and combined effects of individual and neighbourhood socio-economic disadvantage on health-related lifestyle risk factors: a multilevel analysis

Autoren: Yinjie Zhu, Ming-Jie Duan, Ineke J Riphagen, Isidor Minovic, Jochen O Mierau, Juan-Jesus Carrero, Stephan J L Bakker, Gerjan J Navis, Louise H Dekker
Veröffentlicht in: International Journal of Epidemiology, 2021, ISSN 0300-5771
Herausgeber: Oxford University Press
DOI: 10.1093/ije/dyab079

Plasma C-Peptide and Risk of Developing Type 2 Diabetes in the General Population

Autoren: Sokooti S, Kieneker LM, de Borst MH, Muller Kobold A, Kootstra-Ros JE, Gloerich J, van Gool AJ, Lambers Heerspink HJ, Gansevoort RT, Dullaart RPF, Bakker SJL
Veröffentlicht in: Journal of Clinical Medicine, 2020, ISSN 2077-0383
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9093001

Changes in blood pressure thresholds for initiating antihypertensive medication in patients with diabetes: a repeated cross-sectional study focusing on the impact of age and frailty

Autoren: Martina Ambrož, Sieta T de Vries, Grigory Sidorenkov, Klaas Hoogenberg, Petra Denig
Veröffentlicht in: BMJ Open, Ausgabe 10/9, 2020, Seite(n) e037694, ISSN 2044-6055
Herausgeber: BMJ Publishing Group
DOI: 10.1136/bmjopen-2020-037694

Effects of Education and Income on Incident Type 2 Diabetes and Cardiovascular Diseases: a Dutch Prospective Study

Autoren: Ming-Jie F Duan, Yinjie Zhu, Louise H Dekker, Jochen O Mierau, Eva Corpeleijn, Stephan J L Bakker, Gerjan Navis
Veröffentlicht in: Journal of general internal medicine, 2022, ISSN 0884-8734
Herausgeber: Blackwell Publishing Inc.
DOI: 10.1007/s11606-022-07548-8

Metabolic features and glucocorticoid-induced comorbidities in patients with giant cell arteritis and polymyalgia rheumatica in a Dutch and Danish cohort

Autoren: Idil Esen, Suzanne Arends, Berit Dalsgaard Nielsen, Philip Therkildsen, Ib Hansen, Anna van 't Ende, Peter Heeringa, Annemieke Boots, Ellen Hauge, Elisabeth Brouwer, Yannick van Sleen
Veröffentlicht in: RMD Open, 2023, ISSN 2056-5933
Herausgeber: BMJ Publishing Group Ltd
DOI: 10.1136/rmdopen-2022-002640

Prediction of the Effects of Empagliflozin on Cardiovascular and Kidney Outcomes Based on Short-Term Changes in Multiple Risk Markers

Autoren: Sok Cin Tye, Sieta T. de Vries, Christoph Wanner, Petra Denig, Hiddo J. L. Heerspink
Veröffentlicht in: Front Pharmacol, 2021, ISSN 1663-9812
Herausgeber: Frontiers Media S.A.
DOI: 10.3389/fphar.2021.786706

Epigenetic regulation in macrophage migration inhibitory factor (MIF)-mediated signaling in cancer and inflammation

Autoren: Angelina Osipyan, Deng Chen, Frank J. Dekker
Veröffentlicht in: Drug Discovery Today, 2021, ISSN 1359-6446
Herausgeber: Elsevier BV
DOI: 10.1016/j.drudis.2021.03.012

Sex Differences in Lipid Profile across the Life Span in Patients with Type 2 Diabetes: A Primary Care-Based Study

Autoren: Martina Ambrož, Sieta T. de Vries, Priya Vart, Robin P. F. Dullaart, Jeanine Roeters van Lennep, Petra Denig, Klaas Hoogenberg
Veröffentlicht in: Journal of Clinical Medicine, Ausgabe 10/8, 2021, Seite(n) 1775, ISSN 2077-0383
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10081775

Precision medicine approaches for diabetic kidney disease: opportunities and challenges

Autoren: Sok Cin Tye, Petra Denig, Hiddo J L Heerspink
Veröffentlicht in: Nephrology Dialysis Transplantation, Ausgabe 36/Supplement_2, 2021, Seite(n) 3-9, ISSN 0931-0509
Herausgeber: Oxford University Press
DOI: 10.1093/ndt/gfab045

Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells

Autoren: Zhangping Xiao, Angelina Osipyan, Shanshan Song, Deng Chen, Reinder A. Schut, Ronald van Merkerk, Petra E. van der Wouden, Robbert H. Cool, Wim J. Quax, Barbro N. Melgert, Gerrit J. Poelarends, and Frank J. Dekker
Veröffentlicht in: J Med Chem, 2022, ISSN 0022-2623
Herausgeber: American Chemical Society
DOI: 10.1021/acs.jmedchem.1c01598

Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae

Autoren: Noura Faraj, B. H. Peter Duinkerken, Elizabeth C. Carroll, Ben N. G. Giepmans
Veröffentlicht in: FEBS Lett, 2022, ISSN 1873-3468
Herausgeber: John Wiley & Sons, Inc
DOI: 10.1002/1873-3468.14411

Clinical utility of the 4S-AF scheme in predicting progression of atrial fibrillation: data from the RACE V study

Autoren: Vicente Artola Arita, Martijn E Van De Lande, Neda Khalilian Ekrami, Bao-Oanh Nguyen, Joost M Van Melle, Bastiaan Geelhoed, Ruben R De With, Vanessa Weberndörfer, Ömer Erküner, Hans Hillege, Dominik Linz, Hugo Ten Cate, Henri M H Spronk, Tim Koldenhof, Robert G Tieleman, Ulrich Schotten, Harry J G M Crijns, Isabelle C Van Gelder, Michiel Rienstra
Veröffentlicht in: Europace, 2023, ISSN 1532-2092
Herausgeber: Oxford University Press
DOI: 10.1093/europace/euac268

Impaired IL-6-induced JAK-STAT signaling in CD4+ T cells associates with longer treatment duration in giant cell arteritis

Autoren: Idil Esen, Maria Sandovici, Peter Heeringa, Annemieke M.H. Boots, Elisabeth Brouwer, Yannick van Sleen, Wayel Abdulahad
Veröffentlicht in: Journal of Autoimmunity, Ausgabe 146, 2024, ISSN 1095-9157
Herausgeber: Elsevier
DOI: 10.1016/j.jaut.2024.103215

Using Structural Equation Modeling to Untangle Pathways of Risk Factors Associated with Incident Type 2 Diabetes: the Lifelines Cohort Study

Autoren: Ming-Jie Duan, Louise H Dekker, Juan-Jesus Carrero, Gerjan Navis
Veröffentlicht in: Prevention science, 2022, ISSN 1389-4986
Herausgeber: Kluwer Academic Publishers
DOI: 10.1007/s11121-022-01357-5

Association between socioeconomic status and self-reported, tested and diagnosed COVID-19 status during the first wave in the Northern Netherlands: a general population-based cohort from 49 474 adults

Autoren: Yinjie Zhu, Ming-Jie Duan, Hermien H. Dijk, Roel D. Freriks, Louise H. Dekker, Jochen O. Mierau
Veröffentlicht in: BMJ Open, Ausgabe 11/3, 2021, Seite(n) e048020, ISSN 2044-6055
Herausgeber: BMJ Publishing Group
DOI: 10.1136/bmjopen-2020-048020

Initiation of the SGLT2 inhibitor canagliflozin to prevent kidney and heart failure outcomes guided by HbA1c, albuminuria, and predicted risk of kidney failure

Autoren: Sok Cin Tye, Niels Jongs, Steven G. Coca, Johan Sundström, Clare Arnott, Bruce Neal, Vlado Perkovic, Kenneth W. Mahaffey, Priya Vart, Hiddo. J. L. Heerspink
Veröffentlicht in: Cardiovasc Diabetol, 2022, ISSN 1475-2840
Herausgeber: BioMed Central
DOI: 10.1186/s12933-022-01619-0

Distinct Pathological Pathways in Patients With Heart Failure and Diabetes

Autoren: Jasper Tromp, Adriaan A Voors, Abhinav Sharma, João P Ferreira, Wouter Ouwerkerk, Hans L Hillege, Karla A Gomez, Kenneth Dickstein, Stefan D Anker, Marco Metra, Chim C Lang, Leong L Ng, Pim van der Harst, Dirk J van Veldhuisen, Peter van der Meer, Carolyn S P Lam, Faiez Zannad, Iziah E Sama
Veröffentlicht in: JACC Heart Fail, 2020, ISSN 2213-1779
Herausgeber: Elsevier BV
DOI: 10.1016/j.jchf.2019.11.005

Human iPSC-Derived Cardiomyocytes of Peripartum Patients With Cardiomyopathy Reveal Aberrant Regulation of Lipid Metabolism

Autoren: Martijn F. Hoes, Nils Bomer, Melanie Ricke-Hoch, Tristan V. de Jong, Karla F. Arevalo Gomez, Stefan Pietzsch, Denise Hilfiker-Kleiner, Peter van der Meer
Veröffentlicht in: Circulation, 2020, ISSN 1524-4539
Herausgeber: Lippincott Williams & Wilkins
DOI: 10.1161/circulationaha.119.044962

Remnant lipoprotein cholesterol is associated with incident new onset diabetes after transplantation (NODAT) in renal transplant recipients: results of the TransplantLines Biobank and cohort Studies

Autoren: Tamas Szili-Torok, Sara Sokooti, Maryse C J Osté, Antonio W Gomes-Neto, Robin P F Dullaart, Stephan J L Bakker, Uwe J F Tietge
Veröffentlicht in: Cardiovascular diabetology, Ausgabe 21, 2022, Seite(n) 41, ISSN 1475-2840
Herausgeber: BioMed Central
DOI: 10.1186/s12933-022-01475-y

Gain-of-function mutation in ubiquitin-ligase KLHL24 causes desmin degradation and dilatation in hiPSC-derived engineered heart tissues

Autoren: Mathilde Csc Vermeer, Maria C Bolling, Jacqueline M Bliley, Karla F Arevalo Gomez, Mario G Pavez-Giani, Duco Kramer, Pedro H Romero-Herrera, B Daan Westenbrink, Gilles Fh Diercks, Maarten P van den Berg, Adam W Feinberg, Herman H W Silljé, Peter van der Meer
Veröffentlicht in: J Clin Invest, 2021, ISSN 0021-9738
Herausgeber: American Society for Clinical Investigation
DOI: 10.1172/jci140615

Chemoenzymatic Asymmetric Synthesis of Complex Heterocycles: Dihydrobenzoxazinones and Dihydroquinoxalinones

Autoren: Mohammad Faizan Bhat, Alejandro Prats Luján, Mohammad Saifuddin, Gerrit J. Poelarends
Veröffentlicht in: ACS Catal, 2022, ISSN 2155-5435
Herausgeber: American Chemical Society
DOI: 10.1021/acscatal.2c03008

Prediction of the Effects of Liraglutide on Kidney and Cardiovascular Outcomes Based on Short-Term Changes in Multiple Risk Markers

Autoren: Sok Cin Tye, Sieta T. de Vries, Johannes F. E. Mann, Meir Schechter, Ofri Mosenzon, Petra Denig, Hiddo J. L. Heerspink
Veröffentlicht in: Front Pharmacol, 2022, ISSN 1663-9812
Herausgeber: Frontiers Media S.A.
DOI: 10.3389/fphar.2022.786767

The importance of targeting multiple risk markers in patients with type 2 diabetes: A post-hoc study from the CANVAS programme

Autoren: Sok Cin Tye, Megumi Oshima, Clare Arnott, Brendon L. Neuen, Robert A. Fletcher, Bruce Neal, Hiddo J. L. Heerspink
Veröffentlicht in: Diabetes Obes Metab, 2023, ISSN 1462-8902
Herausgeber: Blackwell Publishing Inc.
DOI: 10.1111/dom.15018

A novel drug response score more accurately predicts renoprotective drug effects than existing renal risk scores

Autoren: Nienke M. A. Idzerda, Sok Cin Tye, Dick de Zeeuw, Hiddo J. L. Heerspink
Veröffentlicht in: Therapeutic Advances in Endocrinology and Metabolism, Ausgabe 12, 2021, Seite(n) 204201882097419, ISSN 2042-0188
Herausgeber: Sage Periodicals Press
DOI: 10.1177/2042018820974191

Association of asthma genetic variants with asthma‐associated traits reveals molecular pathways of eosinophilic asthma

Autoren: Zaid W. El‐Husseini, Judith M. Vonk, Maarten van den Berge, Reinoud Gosens, Gerard H. Koppelman
Veröffentlicht in: Clin Transl Allergy, 2023, ISSN 2045-7022
Herausgeber: John Wiley and Sons, Ltd
DOI: 10.1002/clt2.12239

Clinical Outcome in KLHL24 Cardiomyopathy

Autoren: Mathilde C.S.C. Vermeer, Karla F. Arevalo Gomez, Martijn F. Hoes, Jasper Tromp, Job A.J. Verdonschot, Michiel T.H.M. Henkens, Herman H.W. Silljé, Maria C. Bolling, Peter van der Meer
Veröffentlicht in: Circ Genom Precis Med, 2023, ISSN 2574-8300
Herausgeber: Lippincott Williams & Wilkins
DOI: 10.1161/circgen.122.003998

Ultraprocessed food consumption and kidney function decline in a population-based cohort in the Netherlands

Autoren: Qingqing Cai, Ming-Jie Duan, Louise H Dekker, Juan Jesús Carrero, Carla Maria Avesani, Stephan J L Bakker, Martin H de Borst, Gerjan J Navis
Veröffentlicht in: The American journal of clinical nutrition, Ausgabe 116, 2022, Seite(n) 263-273, ISSN 0002-9165
Herausgeber: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqac073

What Factors Make EU Regulators Want to Communicate Drug Safety Issues Related to SGLT2 Inhibitors? An Online Survey Study

Autoren: Sonia Roldan Munoz, Douwe Postmus, Sieta T. de Vries, Liana Gross-Martirosyan, Priya Bahri, Hans Hillege, Peter G. M. Mol
Veröffentlicht in: Drug Saf, 2023, ISSN 0114-5916
Herausgeber: Adis International Ltd.
DOI: 10.1007/s40264-022-01270-4

Lifestyle patterns and incident type 2 diabetes in the Dutch lifelines cohort study

Autoren: Ming-Jie Duan, Louise H. Dekker, Juan-Jesus Carrero, Gerjan Navis
Veröffentlicht in: Prev Med Rep, 2022, ISSN 2211-3355
Herausgeber: Elsevier BV
DOI: 10.1016/j.pmedr.2022.102012

Different circulating biomarkers in women and men with paroxysmal atrial fibrillation: results from the AF-RISK and RACE V studies

Autoren: Ruben R De With, Vicente Artola Arita, Bao-Oanh Nguyen, Dominik Linz, Hugo Ten Cate, Henri Spronk, Ulrich Schotten, Anton Jan van Zonneveld, Ömer Erküner, M Agustina Bayón, Anders S Schmidt, Justin G L M Luermans, Harry J G M Crijns, Isabelle C Van Gelder, Michiel Rienstra
Veröffentlicht in: EP Europace, 2021, ISSN 1099-5129
Herausgeber: Oxford University Press
DOI: 10.1093/europace/euab179

Meta-Inflammation and Metabolic Reprogramming of Macrophages in Diabetes and Obesity: The Importance of Metabolites

Autoren: Sara Russo, Marcel Kwiatkowski, Natalia Govorukhina, Rainer Bischoff, Barbro N Melgert
Veröffentlicht in: Frontiers in Immunology, Ausgabe 12, 2021, Seite(n) 746151, ISSN 1664-3224
Herausgeber: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.746151.

Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles

Autoren: Qian Wang, Angelina Osipyan, Markella Konstantinidou, Roberto Butera, Kumchok C. Mgimpatsang, Svitlana V. Shishkina, Alexander Dömling
Veröffentlicht in: The Journal of Organic Chemistry, 2019, ISSN 0022-3263
Herausgeber: American Chemical Society
DOI: 10.1021/acs.joc.9b01258

Differences in medication beliefs between pregnant women using medication, or not, for chronic diseases: a cross-sectional, multinational, web-based study

Autoren: Sonia Roldan Munoz, Angela Lupattelli, Sieta T de Vries, Peter G M Mol, Hedvig Nordeng
Veröffentlicht in: BMJ Open, Ausgabe 10/2, 2020, Seite(n) e034529, ISSN 2044-6055
Herausgeber: BMJ Publishing Group
DOI: 10.1136/bmjopen-2019-034529

Automated, Accelerated Nanoscale Synthesis of Iminopyrrolidines

Autoren: Angelina Osipyan, Shabnam Shaabani, Robert Warmerdam, Svitlana V. Shishkina, Harry Boltz, Alexander Dömling
Veröffentlicht in: Angewandte Chemie International Edition, 2020, ISSN 1433-7851
Herausgeber: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202000887

High-Density Lipoprotein Particles and Their Relationship to Posttransplantation Diabetes Mellitus in Renal Transplant Recipients

Autoren: Sara Sokooti, Tamas Szili-Torok, Jose L. Flores-Guerrero, Maryse C. J. Osté, António W. Gomes-Neto, Jenny E. Kootstra-Ros, Hiddo J.L. Heerspink, Margery A. Connelly, Stephan J. L. Bakker, Robin P. F. Dullaart
Veröffentlicht in: Biomolecules, Ausgabe 10/3, 2020, Seite(n) 481, ISSN 2218-273X
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/biom10030481

A personalised screening strategy for diabetic retinopathy: a cost-effectiveness perspective

Autoren: Sajad Emamipour, Amber A. W. A. van der Heijden, Giel Nijpels, Petra Elders, Joline W. J. Beulens, Maarten J. Postma, Job F. M. van Boven, Talitha L. Feenstra
Veröffentlicht in: Diabetologia, 2020, ISSN 0012-186X
Herausgeber: Springer Verlag
DOI: 10.1007/s00125-020-05239-9

Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid

Autoren: Jan Freark de Boer, Hilde D. de Vries, Anna Palmiotti, Rumei Li, Marwah Doestzada, Joanne A. Hoogerland, Jingyuan Fu, Anouk M. La Rose, Marit Westerterp, Niels L. Mulder, Milaine V. Hovingh, Martijn Koehorst, Niels J. Kloosterhuis, Justina C. Wolters, Vincent W. Bloks, Joel T. Haas, David Dombrowicz, Bart Staels, Bart van de Sluis, Folkert Kuipers
Veröffentlicht in: Cellular and Molecular Gastroenterology and Hepatology, Ausgabe 11/4, 2021, Seite(n) 1045-1069, ISSN 2352-345X
Herausgeber: Elsevier Inc.
DOI: 10.1016/j.jcmgh.2020.12.004•

Preferences about Future Alzheimer’s Disease Treatments Elicited through an Online Survey Using the Threshold Technique

Autoren: Sonia Roldan Munoz, S. T. de Vries, G. Lankester, F. Pignatti, B. C. van Munster, I. Radford, L. Guizzaro, P. G. M. Mol, H. Hillege, D. Postmus
Veröffentlicht in: The Journal of Prevention of Alzheimer's Disease, 2023, ISSN 2426-0266
Herausgeber: Springer
DOI: 10.14283/jpad.2023.84

Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70 -/- mice by reducing fat absorption

Autoren: Rumei Li, Anna Palmiotti, Hilde D de Vries, Milaine V Hovingh, Martijn Koehorst, Niels L Mulder, Yue Zhang, Kim Kats, Vincent W Bloks, Jingyuan Fu, Henkjan J Verkade, Jan Freark de Boer, Folkert Kuipers
Veröffentlicht in: Journal of lipid research, Ausgabe 62, 2021, Seite(n) 100134, ISSN 0022-2275
Herausgeber: Lipid Research, Inc.
DOI: 10.1016/j.jlr.2021.100134

Atrial function in paroxysmal AF patients withand without heart failure with preservedejection fraction: Data from the AF-RISK study

Autoren: Vicente Artola Arita, Bernadet T Santema, Ruben R De With, Bao-Oanh Nguyen, Dominik Linz, Ulrich Schotten, Isabelle C Van Gelder, Harry Jgm Crijns, Adriaan A Voors, Michiel Rienstra
Veröffentlicht in: American Heart Journal, Ausgabe 244, 2022, Seite(n) 36-41, ISSN 0002-8703
Herausgeber: Mosby Inc.
DOI: 10.1016/j.ahj.2021.10.183

The genetics of asthma and the promise of genomics-guided drug target discovery

Autoren: Zaid W El-Husseini, Reinoud Gosens, Frank Dekker, Gerard H Koppelman
Veröffentlicht in: The Lancet Respiratory Medicine, 2020, ISSN 2213-2600
Herausgeber: Elsevier Limited
DOI: 10.1016/s2213-2600(20)30363-5

Sex disparities in medication prescribing amongst patients with type 2 diabetes mellitus managed in primary care

Autoren: Martina Ambrož, Marit Geelink, Kirsten P.J. Smits, Sieta T. de Vries, Petra Denig
Veröffentlicht in: Diabet Med, 2023, ISSN 1464-5491
Herausgeber: Wiley
DOI: 10.1111/dme.14987

Trends in HbA1c thresholds for initiation of hypoglycemic agents: Impact of changed recommendations for older and frail patients

Autoren: Martina Ambrož, Sieta T. de Vries, Klaas Hoogenberg, Petra Denig
Veröffentlicht in: Pharmacoepidemiology and Drug Safety, 2020, ISSN 1099-1557
Herausgeber: John Wiley & Sons Ltd
DOI: 10.1002/pds.5129

Chemo- and Enantioselective Photoenzymatic Ketone Reductions Using a Promiscuous Flavin-dependent Nitroreductase

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Veröffentlicht in: ChemCatChem, 2022, ISSN 1867-3899
Herausgeber: Chemistry Europe
DOI: 10.1002/cctc.202200043

Fasting Proinsulin Independently Predicts Incident Type 2 Diabetes in the General Population

Autoren: Sara Sokooti, Wendy A Dam, Tamas Szili-Torok, Jolein Gloerich, Alain J van Gool, Adrian Post, Martin H de Borst, Ron T Gansevoort, Hiddo J L Heerspink, Robin P F Dullaart, Stephan J L Bakker
Veröffentlicht in: Journal of personalized medicine, Ausgabe 12, 2022, Seite(n) 1131, ISSN 2075-4426
Herausgeber: MDPI
DOI: 10.3390/jpm12071131

Differences in Importance Attached to Drug Effects Between Patients With Type 2 Diabetes From the Netherlands and Turkey: A Preference Study

Autoren: Sonia Roldan Munoz, Douwe Postmus, Sieta T. de Vries, Arna H. Arnardottir, İlknur Dolu, Hans Hillege, Peter G. M. Mol
Veröffentlicht in: Frontiers in Pharmacology, Ausgabe 11, 2021, ISSN 1663-9812
Herausgeber: Frontiers Media S.A.
DOI: 10.3389/fphar.2020.617409

Emerging roles of bile acids in control of intestinal functions

Autoren: Jiufang Yang, Anna Palmiotti, Folkert Kuipers
Veröffentlicht in: Current opinion in clinical nutrition and metabolic care, Ausgabe 24, 2021, Seite(n) 127-133, ISSN 1363-1950
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/mco.0000000000000709

Triglyceride-rich lipoprotein and LDL particle subfractions and their association with incident type 2 diabetes: the PREVEND study

Autoren: Sara Sokooti, Jose L. Flores-Guerrero, Hiddo J. L. Heerspink, Margery A. Connelly, Stephan J. L. Bakker, Robin P. F. Dullaart
Veröffentlicht in: Cardiovascular Diabetology, Ausgabe 20/1, 2021, ISSN 1475-2840
Herausgeber: BioMed Central
DOI: 10.1186/s12933-021-01348-w

Lipoprotein particle sizes and incident type 2 diabetes: the PREVEND cohort study

Autoren: Sara Sokooti, José L. Flores-Guerrero, Hiddo J. L. Heerspink, Erwin Garcia, Margery A. Connelly, Stephan J. L. Bakker, Robin P. F. Dullaart
Veröffentlicht in: Diabetologia, 2021, ISSN 1432-0428
Herausgeber: Springer
DOI: 10.1007/s00125-021-05603-3

Functionally Heterogenous Macrophage Subsets in the Pathogenesis of Giant Cell Arteritis: Novel Targets for Disease Monitoring and Treatment

Autoren: Idil Esen, William F. Jiemy, Yannick van Sleen, Kornelis S.M. van der Geest, Maria Sandovici, Peter Heeringa, Annemieke M. H. Boots, Elisabeth Brouwer
Veröffentlicht in: Journal of Clinical Medicine, 2021, ISSN 2077-0383
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10214958

Ultra-processed food and incident type 2 diabetes: studying the underlying consumption patterns to unravel the health effects of this heterogeneous food category in the prospective Lifelines cohort

Autoren: Ming-Jie Duan, Petra C. Vinke, Gerjan Navis, Eva Corpeleijn, Louise H. Dekker
Veröffentlicht in: BMC Medicine, 2022, ISSN 1741-7015
Herausgeber: BioMed Central
DOI: 10.1186/s12916-021-02200-4

Collagen type I alters the proteomic signature of macrophages in a collagen morphology-dependent manner

Autoren: Gwenda F. Vasse, Sara Russo, Andrei Barcaru, Asmaa A. A. Oun, Amalia M. Dolga, Patrick van Rijn, Marcel Kwiatkowski, Natalia Govorukhina, Rainer Bischoff, Barbro N. Melgert
Veröffentlicht in: Sci Rep, 2023, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-023-32715-0

Autoren: Ming-Jie Duan, Louise H. Dekker, Juan-Jesus Carrero, Gerjan Navis
Veröffentlicht in: Clinical Nutrition, Ausgabe 40/7, 2021, Seite(n) 4712-4719, ISSN 0261-5614
Herausgeber: Churchill Livingstone
DOI: 10.1016/j.clnu.2021.04.046

Ultra-processed foods and risk of all-cause mortality in renal transplant recipients

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Veröffentlicht in: The American journal of clinical nutrition, Ausgabe 115, 2022, Seite(n) 1646-1657, ISSN 0002-9165
Herausgeber: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqac053

Association of diuretic use with increased risk for long-term post-transplantation diabetes mellitus in kidney transplant recipients

Autoren: Sara Sokooti, Frank Klont, Sok Cin Tye, Daan Kremer, Rianne M Douwes, Gérard Hopfgartner, Robin P F Dullaart, Hiddo J L Heerspink, Stephan J L Bakker
Veröffentlicht in: Nephrology, diabetes, transplantation, Ausgabe 37, 2022, Seite(n) 1375-1383, ISSN 0931-0509
Herausgeber: Oxford University Press
DOI: 10.1093/ndt/gfac012

Circulating FGF21 Concentration, Fasting Plasma Glucose, and the Risk of Type 2 Diabetes: Results From the PREVEND Study

Autoren: Adrian Post, Wendy A Dam, Sara Sokooti, Dion Groothof, Jolein Gloerich, Alain J van Gool, Daan Kremer, Ron T Gansevoort, Jacob van den Born, Ido P Kema, Casper F M Franssen, Robin P F Dullaart, Stephan J L Bakker
Veröffentlicht in: J Clin Endocrinol Metab, 2023, ISSN 0021-972X
Herausgeber: The Endocrine Society
DOI: 10.1210/clinem/dgac729

Plasma Pyruvate Kinase M2 as a marker of vascular inflammation in giant cell arteritis

Autoren: Idil Esen, William F Jiemy, Yannick van Sleen, Johan Bijzet, Daniel M de Jong, Pieter H Nienhuis, Riemer H J A Slart, Peter Heeringa, Annemieke M H Boots, Elisabeth Brouwer
Veröffentlicht in: Rheumatology, 2021, ISSN 1462-0332
Herausgeber: Oxford Academic
DOI: 10.1093/rheumatology/keab814

Androgens and Development of Posttransplantation Diabetes Mellitus in Male Kidney Transplant Recipients: A Post Hoc Analysis of a Prospective Study

Autoren: Suzanne P Stam, Sara Sokooti, Michele F Eisenga, Anna van der Veen, António W Gomes-Neto, Peter R van Dijk, Jelmer J van Zanden, Michel J Vos, Ido P Kema, André P van Beek, Stephan J L Bakker, TransplantLines Investigators
Veröffentlicht in: Diabetes Care, Ausgabe 44, 2021, Seite(n) 2683-2690, ISSN 0149-5992
Herausgeber: American Diabetes Association
DOI: 10.2337/dc21-0237

Bile Acid Sequestration by Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70-/- Mice with a Human-Like Bile Acid Composition

Autoren: Anna Palmiotti, Hilde D. de Vries, Milaine V. Hovingh, Martijn Koehorst, Niels L. Mulder, Esther Verkade, Melany K. Veentjer, Theo H. van Dijk, Vincent W. Bloks, Rick Havinga, Henkjan J. Verkade, Jan Freark de Boer, Folkert Kuipers
Veröffentlicht in: Preprints, 2023, ISSN 2310-287X
Herausgeber: Preprints
DOI: 10.20944/preprints202308.0779.v1

Comment on: Plasma Pyruvate Kinase M2 as a marker of vascular inflammation in giant cell arteritis: reply

Autoren: Idil Esen, William F Jiemy, Yannick van Sleen, Rosanne D Reitsema, Johan Bijzet, Daniel M de Jong, Pieter H Nienhuis, Riemer H J A Slart, Peter Heeringa, Annemieke M H Boots, Elisabeth Brouwer
Veröffentlicht in: Rheumatology (Oxford), 2022, ISSN 1462-0324
Herausgeber: Oxford University Press
DOI: 10.1093/rheumatology/keac093

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