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Tissue regeneration and aging: the decisive quiescent stem-cell state

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Musculoskeletal senescence: a moving target ready to be eliminated

Author(s): Marjolein P Baar, Eusebio Perdiguero, Pura Muñoz-Cánoves, Peter LJ de Keizer
Published in: Current Opinion in Pharmacology, Issue 40, 2018, Page(s) 147-155, ISSN 1471-4892
DOI: 10.1016/j.coph.2018.05.007

Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress

Author(s): Guiomar Solanas, Francisca Oliveira Peixoto, Eusebio Perdiguero, Mercè Jardí, Vanessa Ruiz-Bonilla, Debayan Datta, Aikaterini Symeonidi, Andrés Castellanos, Patrick-Simon Welz, Juan Martín Caballero, Paolo Sassone-Corsi, Pura Muñoz-Cánoves, Salvador Aznar Benitah
Published in: Cell, Issue 170/4, 2017, Page(s) 678-692.e20, ISSN 0092-8674
DOI: 10.1016/j.cell.2017.07.035

New mechanisms driving muscle stem cell regenerative decline with aging

Author(s): Pedro Sousa-Victor, Laura García-Prat, Pura Muñoz-Cánoves
Published in: The International Journal of Developmental Biology, Issue 62/6-7-8, 2018, Page(s) 583-590, ISSN 0214-6282
DOI: 10.1387/ijdb.180041pm

Definitions for adult stem cells debated

Author(s): Pura Muñoz-Cánoves, Meritxell Huch
Published in: Nature, Issue 563/7731, 2018, Page(s) 328-329, ISSN 0028-0836
DOI: 10.1038/d41586-018-07175-6

The Dystrophin Glycoprotein Complex Regulates the Epigenetic Activation of Muscle Stem Cell Commitment

Author(s): Natasha C. Chang, Marie-Claude Sincennes, Fabien P. Chevalier, Caroline E. Brun, Melanie Lacaria, Jessica Segalés, Pura Muñoz-Cánoves, Hong Ming, Michael A. Rudnicki
Published in: Cell Stem Cell, Issue 22/5, 2018, Page(s) 755-768.e6, ISSN 1934-5909
DOI: 10.1016/j.stem.2018.03.022

Cilia Control Fat Deposition during Tissue Repair

Author(s): Eusebio Perdiguero, Antonio L. Serrano, Pura Muñoz-Cánoves
Published in: Developmental Cell, Issue 42/2, 2017, Page(s) 114-116, ISSN 1534-5807
DOI: 10.1016/j.devcel.2017.06.023

Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment

Author(s): Giorgia Testoni, Jordi Duran, Mar García-Rocha, Francisco Vilaplana, Antonio L. Serrano, David Sebastián, Iliana López-Soldado, Mitchell A. Sullivan, Felipe Slebe, Marta Vilaseca, Pura Muñoz-Cánoves, Joan J. Guinovart
Published in: Cell Metabolism, Issue 26/1, 2017, Page(s) 256-266.e4, ISSN 1550-4131
DOI: 10.1016/j.cmet.2017.06.008

Cellular Senescence Is Associated With Human Retinal Microaneurysm Formation During Aging

Author(s): Mariana López-Luppo, Joana Catita, David Ramos, Marc Navarro, Ana Carretero, Luísa Mendes-Jorge, Pura Muñoz-Cánoves, Alfonso Rodriguez-Baeza, Victor Nacher, Jesus Ruberte
Published in: Investigative Opthalmology & Visual Science, Issue 58/7, 2017, Page(s) 2832, ISSN 1552-5783
DOI: 10.1167/iovs.16-20312

Proteostatic and Metabolic Control of Stemness

Author(s): Laura García-Prat, Pedro Sousa-Victor, Pura Muñoz-Cánoves
Published in: Cell Stem Cell, Issue 20/5, 2017, Page(s) 593-608, ISSN 1934-5909
DOI: 10.1016/j.stem.2017.04.011

Genetic Rescue of Mitochondrial and Skeletal Muscle Impairment in an Induced Pluripotent Stem Cells Model of Coenzyme Q 10 Deficiency

Author(s): Damià Romero-Moya, Carlos Santos-Ocaña, Julio Castaño, Gloria Garrabou, José A. Rodríguez-Gómez, Vanesa Ruiz-Bonilla, Clara Bueno, Patricia González-Rodríguez, Alessandra Giorgetti, Eusebio Perdiguero, Cristina Prieto, Constanza Moren-Nuñez, Daniel J. Fernández-Ayala, Maria Victoria Cascajo, Iván Velasco, Josep Maria Canals, Raquel Montero, Delia Yubero, Cristina Jou, José López-Barne
Published in: STEM CELLS, Issue 35/7, 2017, Page(s) 1687-1703, ISSN 1066-5099
DOI: 10.1002/stem.2634

Rejuvenating stem cells to restore muscle regeneration in aging

Author(s): Eyal Bengal, Eusebio Perdiguero, Antonio L. Serrano, Pura Muñoz-Cánoves
Published in: F1000Research, Issue 6, 2017, Page(s) 76, ISSN 2046-1402
DOI: 10.12688/f1000research.9846.1

Fibrosis development in early-onset muscular dystrophies: Mechanisms and translational implications

Author(s): Antonio L. Serrano, Pura Muñoz-Cánoves
Published in: Seminars in Cell & Developmental Biology, Issue 64, 2017, Page(s) 181-190, ISSN 1084-9521
DOI: 10.1016/j.semcdb.2016.09.013

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

Author(s): Jessica Segalés, Eusebio Perdiguero, Antonio L. Serrano, Pedro Sousa-Victor, Laura Ortet, Mercè Jardí, Andrei V. Budanov, Laura Garcia-Prat, Marco Sandri, David M. Thomson, Michael Karin, Jun Hee Lee, Pura Muñoz-Cánoves
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-019-13832-9

Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles

Author(s): Krishnamoorthy Sreenivasan, Alessandro Ianni, Carsten Künne, Boris Strilic, Stefan Günther, Eusebio Perdiguero, Marcus Krüger, Simone Spuler, Stefan Offermanns, Pablo Gómez-del Arco, Juan Miguel Redondo, Pura Munoz-Canoves, Johnny Kim, Thomas Braun
Published in: Cell Reports, Issue 31/7, 2020, Page(s) 107652, ISSN 2211-1247
DOI: 10.1016/j.celrep.2020.107652

Muscle stem cell aging: identifying ways to induce tissue rejuvenation

Author(s): Pedro Sousa-Victor, Joana Neves, Pura Muñoz-Cánoves
Published in: Mechanisms of Ageing and Development, Issue 188, 2020, Page(s) 111246, ISSN 0047-6374
DOI: 10.1016/j.mad.2020.111246

Cripto shapes macrophage plasticity and restricts EndMT in injured and diseased skeletal muscle

Author(s): Francescopaolo Iavarone, Ombretta Guardiola, Alessandra Scagliola, Gennaro Andolfi, Federica Esposito, Antonio Serrano, Eusebio Perdiguero, Silvia Brunelli, Pura Muñoz‐Cánoves, Gabriella Minchiotti
Published in: EMBO reports, Issue 21/4, 2020, ISSN 1469-221X
DOI: 10.15252/embr.201949075

Understanding muscle regenerative decline with aging: new approaches to bring back youthfulness to aged stem cells

Author(s): Pura Muñoz‐Cánoves, Joana Neves, Pedro Sousa‐Victor
Published in: The FEBS Journal, Issue 287/3, 2020, Page(s) 406-416, ISSN 1742-464X
DOI: 10.1111/febs.15182

Simultaneous Isolation of Stem and Niche Cells of Skeletal Muscle: Applicability for Aging Studies

Author(s): Eusebio Perdiguero, Victoria Moiseeva, Pura Muñoz-Cánoves
Published in: Methods in Molecular Biology, 2019
DOI: 10.1007/7651_2019_210

Monitoring Autophagy in Muscle Stem Cells

Author(s): Laura García-Prat, Pura Muñoz-Cánoves, Marta Martínez-Vicente
Published in: Muscle Stem Cells - Methods and Protocols, Issue 1556, 2017, Page(s) 255-280
DOI: 10.1007/978-1-4939-6771-1_14