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Comparing effectiveness of self-management interventions in 4 high priority chronic diseases in Europe

Objective

COMPAR-EU aims to identify, compare, and rank the most effective and cost-effective self-management interventions (SMIs) for adults in Europe within four high-priority chronic conditions: type 2 diabetes, obesity, chronic obstructive pulmonary disease, and heart failure.

This project addresses an important gap in current knowledge applying network meta-analysis, an extension of meta-analysis methodology that allows multiple (rather than pairwise) comparisons of intervention effectiveness, to randomised controlled trials (RCTs) that meet the study inclusion criteria. This centralised analysis of an estimated 4000 RCTs will substantially help to overcome current problems associated with the dispersion and duplication of evidence. The work will be based on a validated taxonomy of SMIs and will prioritise outcomes from the patients’ perspective.

In addition, a cost-effectiveness of the most effective SMIs will be estimated to provide insights into the economic consequences of adopting SMIs for societies, healthcare budgets, and patients. Contextual factors associated with successful interventions will also be studied. Drawing on our results, we will develop and pilot decision-making tools to facilitate access to evidence-based information on the most effective SMIs to key users through a user-friendly interactive platform. A multiprong strategy for exploitation of the research findings will lead to clear business cases for implementing it in different contexts within the heterogeneous EU health system.

The end goal of the project is to have an impact in supporting policy-makers, guideline developers, researchers, industry, professionals and patients to make informed decisions on the identification and implementation of the most suitable SMIs, therefore contributing to the diffusion of the knowledge, healthcare sustainability and equity and promoting EU competitiveness in a globally emerging market.

Call for proposal

H2020-SC1-2016-2017

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Sub call

H2020-SC1-2017-Two-Stage-RTD

Coordinator

FUNDACION AVEDIS DONABEDIAN PARA LA MEJORA DE LA CALIDAD ASISTENCIAL
Net EU contribution
€ 1 351 930,00
Address
Calle Provenza 293 Pral
08037 Barcelona
Spain

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Region
Este Cataluña Barcelona
Activity type
Other
Non-EU contribution
€ 0,00

Participants (7)

FORUM DES PATIENTS EUROPEENS
Belgium
Net EU contribution
€ 477 458,75
Non-EU contribution
€ 0,00
INSTITUTE FOR MEDICAL TECHNOLOGY ASSESSMENT BV
Netherlands
Net EU contribution
€ 698 535,00
Address
Burgemeester Oudlaan 50
3062PA Rotterdam

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Region
West-Nederland Zuid-Holland Groot-Rijnmond
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

ERASMUS UNIVERSITEIT ROTTERDAM
Netherlands
Net EU contribution
€ 78 065,00
Address
Burgemeester Oudlaan 50
3062 PA Rotterdam

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Region
West-Nederland Zuid-Holland Groot-Rijnmond
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
STICHTING NEDERLANDS INSTITUUT VOOR ONDERZOEK VAN DE GEZONDHEIDSZORG
Netherlands
Net EU contribution
€ 1 278 120,00
Address
Otterstraat 118-124
3500 BN Utrecht

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Region
West-Nederland Utrecht Utrecht
Activity type
Research Organisations
Non-EU contribution
€ 0,00
INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU FUNDACION
Spain
Net EU contribution
€ 777 786,25
Address
C Sant Quinti 77-79
08041 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
OPTIMEDIS AG
Germany
Net EU contribution
€ 733 796,25
Address
Burchardstrasse 17
20095 Hamburg

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Hamburg Hamburg Hamburg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
PANEPISTIMIO IOANNINON
Greece
Net EU contribution
€ 603 275,00
Address
Panepistemioypole Panepistemio Ioanninon
45110 Ioannina

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Region
Ιωάννινα Ήπειρος Βόρεια Ελλάδα
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00