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Comparing effectiveness of self-management interventions in 4 high priority chronic diseases in Europe

Objective

COMPAR-EU aims to identify, compare, and rank the most effective and cost-effective self-management interventions (SMIs) for adults in Europe within four high-priority chronic conditions: type 2 diabetes, obesity, chronic obstructive pulmonary disease, and heart failure.

This project addresses an important gap in current knowledge applying network meta-analysis, an extension of meta-analysis methodology that allows multiple (rather than pairwise) comparisons of intervention effectiveness, to randomised controlled trials (RCTs) that meet the study inclusion criteria. This centralised analysis of an estimated 4000 RCTs will substantially help to overcome current problems associated with the dispersion and duplication of evidence. The work will be based on a validated taxonomy of SMIs and will prioritise outcomes from the patients’ perspective.

In addition, a cost-effectiveness of the most effective SMIs will be estimated to provide insights into the economic consequences of adopting SMIs for societies, healthcare budgets, and patients. Contextual factors associated with successful interventions will also be studied. Drawing on our results, we will develop and pilot decision-making tools to facilitate access to evidence-based information on the most effective SMIs to key users through a user-friendly interactive platform. A multiprong strategy for exploitation of the research findings will lead to clear business cases for implementing it in different contexts within the heterogeneous EU health system.

The end goal of the project is to have an impact in supporting policy-makers, guideline developers, researchers, industry, professionals and patients to make informed decisions on the identification and implementation of the most suitable SMIs, therefore contributing to the diffusion of the knowledge, healthcare sustainability and equity and promoting EU competitiveness in a globally emerging market.

Call for proposal

H2020-SC1-2017-Two-Stage-RTD
See other projects for this call

Coordinator

FUNDACION AVEDIS DONABEDIAN PARA LA MEJORA DE LA CALIDAD ASISTENCIAL
Address
Calle Provenza 293 Pral
08037 Barcelona
Spain
Activity type
Other
EU contribution
€ 1 351 930

Participants (6)

FORUM DES PATIENTS EUROPEENS
Belgium
EU contribution
€ 477 458,75
Address
Chaussee D Etterbeek 180
BRUSSELS 1040
Activity type
Other
INSTITUTE FOR MEDICAL TECHNOLOGY ASSESSMENT BV
Netherlands
EU contribution
€ 776 600
Address
Burgemeester Oudlaan 50
3062PA Rotterdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
STICHTING NEDERLANDS INSTITUUT VOOR ONDERZOEK VAN DE GEZONDHEIDSZORG
Netherlands
EU contribution
€ 1 278 120
Address
Otterstraat 118-124
3500 BN Utrecht
Activity type
Research Organisations
INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU FUNDACION
Spain
EU contribution
€ 777 786,25
Address
C Sant Quinti 77-79
08041 Barcelona
Activity type
Research Organisations
OPTIMEDIS AG
Germany
EU contribution
€ 733 796,25
Address
Burchardstrasse 17
20095 Hamburg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PANEPISTIMIO IOANNINON
Greece
EU contribution
€ 603 275
Address
Panepistemioypole Panepistemio Ioanninon
45110 Ioannina
Activity type
Higher or Secondary Education Establishments