New Chemical Tools for Precision Glycotherapy

Publications

Peer reviewed articles (9)

The Glycosylation Mechanisms of 6,3-Uronic Acid Lactones

Author(s): Hidde Elferink, Rens A. Mensink, Wilke W. A. Castelijns, Oscar Jansen, Jeroen P. J. Bruekers, Jonathan Martens, Jos Oomens, Anouk M. Rijs, Thomas J. Boltje
Published in: Angewandte Chemie International Edition, 58/26, 2019, Page(s) 8746-8751, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201902507

Chemoenzymatic Synthesis of Sialic Acid Derivatives Using Immobilized N‐ Acetylneuraminate Lyase in a Continuous Flow Reactor

Author(s): Victor R. L. J. Bloemendal, Sam J. Moons, Jurriaan J. A. Heming, Mohamed Chayoua, Olaf Niesink, Jan C. M. van Hest, Thomas J. Boltje, Floris P. J. T. Rutjes
Published in: Advanced Synthesis & Catalysis, 2019, ISSN 1615-4150
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adsc.201900146

Sialic acid glycoengineering using N-acetylmannosamine and sialic acid analogs

Author(s): Sam J Moons, Gosse J Adema, Max TGM Derks, Thomas J Boltje, Christian Büll
Published in: Glycobiology, 2019, ISSN 1460-2423
Publisher: oxford academic
DOI: 10.1093/glycob/cwz026

Direct Experimental Characterization of Glycosyl Cations by Infrared Ion Spectroscopy

Author(s): Hidde Elferink, Marion E. Severijnen, Jonathan Martens, Rens A. Mensink, Giel Berden, Jos Oomens, Floris P. J. T. Rutjes, Anouk M. Rijs, Thomas J. Boltje
Published in: Journal of the American Chemical Society, 140/19, 2018, Page(s) 6034-6038, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.8b01236

Potent Metabolic Sialylation Inhibitors Based on C-5-Modified Fluorinated Sialic Acids

Author(s): Torben Heise, Johan F. A. Pijnenborg, Christian Büll, Niek van Hilten, Esther D. Kers-Rebel, Natasja Balneger, Hidde Elferink, Gosse J. Adema, Thomas J. Boltje
Published in: Journal of Medicinal Chemistry, 62/2, 2019, Page(s) 1014-1021, ISSN 0022-2623
Publisher: American Chemical Society
DOI: 10.1021/acs.jmedchem.8b01757

α-Selective Glycosylation with β-Glycosyl Sulfonium Ions Prepared via Intramolecular Alkylation

Author(s): Sam J. Moons, Rens A. Mensink, Jeroen P. J. Bruekers, Maurits L. A. Vercammen, Laura M. Jansen, Thomas J. Boltje
Published in: The Journal of Organic Chemistry, 84/7, 2019, Page(s) 4486-4500, ISSN 0022-3263
Publisher: American Chemical Society
DOI: 10.1021/acs.joc.9b00022

C-2 auxiliaries for stereoselective glycosylation based on common additive functional groups

Author(s): Frank F. J. de Kleijne, Sam J. Moons, Paul B. White, Thomas J. Boltje
Published in: Organic & Biomolecular Chemistry, 18/6, 2020, Page(s) 1165-1184, ISSN 1477-0520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9ob02700a

Characterization of glycosyl dioxolenium ions and their role in glycosylation reactions

Author(s): Thomas Hansen, Hidde Elferink, Jacob M. A. van Hengst, Kas J. Houthuijs, Wouter A. Remmerswaal, Alexandra Kromm, Giel Berden, Stefan van der Vorm, Anouk M. Rijs, Hermen S. Overkleeft, Dmitri V. Filippov, Floris P. J. T. Rutjes, Gijsbert A. van der Marel, Jonathan Martens, Jos Oomens, Jeroen D. C. Codée, Thomas J. Boltje
Published in: Nature Communications, 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-16362-x

Growth on Carbohydrates from Carbonaceous Meteorites Alters the Immunogenicity of Environment-Derived Bacterial Pathogens

Author(s): Jorge Domínguez-Andrés, Marc Eleveld, Georgios Renieris, Thomas J. Boltje, Rob J. Mesman, Laura van Niftrik, Sam J. Moons, Petra Rettberg, Jos W.M. van der Meer, Evangelos J. Giamarellos-Bourboulis, Huub J.M. Op den Camp, Marien I. de Jonge, Mihai G. Netea
Published in: Astrobiology, 2020, ISSN 1531-1074
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ast.2019.2173