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New Chemical Tools for Precision Glycotherapy

Publications

The Glycosylation Mechanisms of 6,3-Uronic Acid Lactones


Published in: ISSN 1433-7851
DOI: 10.1002/anie.201902507

Sialic acid glycoengineering using N-acetylmannosamine and sialic acid analogs

Author(s): Sam J Moons, Gosse J Adema, Max TGM Derks, Thomas J Boltje, Christian Büll
Published in: Glycobiology, 2019, ISSN 1460-2423
DOI: 10.1093/glycob/cwz026

Direct Experimental Characterization of Glycosyl Cations by Infrared Ion Spectroscopy

Author(s): Hidde Elferink, Marion E. Severijnen, Jonathan Martens, Rens A. Mensink, Giel Berden, Jos Oomens, Floris P. J. T. Rutjes, Anouk M. Rijs, Thomas J. Boltje
Published in: Journal of the American Chemical Society, Issue 140/19, 2018, Page(s) 6034-6038, ISSN 0002-7863
DOI: 10.1021/jacs.8b01236

Potent Metabolic Sialylation Inhibitors Based on C-5-Modified Fluorinated Sialic Acids

Author(s): Torben Heise, Johan F. A. Pijnenborg, Christian Büll, Niek van Hilten, Esther D. Kers-Rebel, Natasja Balneger, Hidde Elferink, Gosse J. Adema, Thomas J. Boltje
Published in: Journal of Medicinal Chemistry, Issue 62/2, 2019, Page(s) 1014-1021, ISSN 0022-2623
DOI: 10.1021/acs.jmedchem.8b01757

α-Selective Glycosylation with β-Glycosyl Sulfonium Ions Prepared via Intramolecular Alkylation

Author(s): Sam J. Moons, Rens A. Mensink, Jeroen P. J. Bruekers, Maurits L. A. Vercammen, Laura M. Jansen, Thomas J. Boltje
Published in: The Journal of Organic Chemistry, Issue 84/7, 2019, Page(s) 4486-4500, ISSN 0022-3263
DOI: 10.1021/acs.joc.9b00022

Characterization of glycosyl dioxolenium ions and their role in glycosylation reactions

Author(s): Thomas Hansen, Hidde Elferink, Jacob M. A. van Hengst, Kas J. Houthuijs, Wouter A. Remmerswaal, Alexandra Kromm, Giel Berden, Stefan van der Vorm, Anouk M. Rijs, Hermen S. Overkleeft, Dmitri V. Filippov, Floris P. J. T. Rutjes, Gijsbert A. van der Marel, Jonathan Martens, Jos Oomens, Jeroen D. C. Codée, Thomas J. Boltje
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-16362-x

Growth on Carbohydrates from Carbonaceous Meteorites Alters the Immunogenicity of Environment-Derived Bacterial Pathogens

Author(s): Jorge Domínguez-Andrés, Marc Eleveld, Georgios Renieris, Thomas J. Boltje, Rob J. Mesman, Laura van Niftrik, Sam J. Moons, Petra Rettberg, Jos W.M. van der Meer, Evangelos J. Giamarellos-Bourboulis, Huub J.M. Op den Camp, Marien I. de Jonge, Mihai G. Netea
Published in: Astrobiology, 2020, ISSN 1531-1074
DOI: 10.1089/ast.2019.2173