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INfraStructure in Proton International REsearch

Deliverables

Report Recalculation of treatment plans performed assuming a constant RBE=1.1, with two different models for variable RBE, including dependencies on beam quality, dose fractionation, OER and tissue type

Study of the effects of using a variable RBE on treatment planning and how factors such as fractionation, OER and beam quality affect this plan. Combination of experimental and theoretical studies. Due Date (in months): 36

TNA providers have QA documentation in place

All TNA providers have QA documentation in place on their experimental protocols and operational procedures. For example for dosimetry, spot scanning, energy verification. Due Date (in months): 12

Evaluate detectors for measuring range uncertainties and evaluate opportunities of using nanoparticles to enhance signals

Use nanoparticles to enhance prompt gamma signal for range verification. Evaluate the use of nanoparticles to enhance detector signal. Due Date (in months): 40

Definition of key parameters for NTCP based patient selection and tumour sites

Discussion of key tumour sites and development of NTCP models for those sites. Sharing of results between interested partners. Due Date (in months): 12

Protocols for in vitro analysis of dose response of radio sensitising agents with protons; prepare paper for publication

Establish protocols for in vitro studies of PBT in combination with radio sensitising agents. Prepare paper for publication. Due Date (in months): 36

Preliminary experiments to investigate radio-protective effects of hibernation on small animals, prepare paper for publication

Develop experiments to test the hypothesis that there are radio-protective effects due to hibernation. Prepare paper for publication. Due Date (in months): 40

Data Management Plan & Dissemination & Exploitation Plan

A comprehensive data management plan (DMP) will be drawn up for INSPIRE. A draft of INSPIRE’s dissemination and exploitation plan can be found in section 2.2(a) and its roadmap is shown in Figure 7. Due Date (in months): 5

User selection Panel appointed

Independent reviewers of proposals for TNA appointed and given information on how they expected to review proposals. Due Date (in months): 6

Open Nights programme commenced

INSPIRE will have an “Open Nights” programme for all of the PBT centres who wish to participate. This is an idea that has been pioneered by IFJPAN and allows the opportunity for the public to see around both the research room and the clinical facilities, ask questions and hear about the research being conducted within INSPIRE. Due Date (in months): 12

Incorporation of PBT indications into Malthus decision trees

Incorporating decision trees for UK PBT indications in to Malthus model for modelling radiotherapy demand. Due Date (in months): 12

Access Gateway designed and launched

INSPIRE web portal which comprises INSPIRE Access Gateway (for NA, TNA and JRA) and is specified, designed, tested using a proto-type and then launched so it can be used by partners and the wider EU community. Due Date (in months): 6

Searching for OpenAIRE data...

Publications

Carbon Ion Radiobiology

Author(s): Walter Tinganelli, Marco Durante
Published in: Cancers, Issue 12/10, 2020, Page(s) 3022, ISSN 2072-6694
DOI: 10.3390/cancers12103022

Late Side Effects in Normal Mouse Brain Tissue After Proton Irradiation

Author(s): Theresa Suckert, Elke Beyreuther, Johannes Müller, Behnam Azadegan, Matthias Meinhardt, Felix Raschke, Elisabeth Bodenstein, Cläre von Neubeck, Armin Lühr, Mechthild Krause, Antje Dietrich
Published in: Frontiers in Oncology, Issue 10, 2021, ISSN 2234-943X
DOI: 10.3389/fonc.2020.598360

Multi-modality bedding platform for combined imaging and irradiation of mice

Author(s): Johannes Müller, Michael Schürer, Christian Neubert, Falk Tillner, Elke Beyreuther, Theresa Suckert, Nils Peters, Cläre von Neubeck, Armin Lühr, Mechthild Krause, Rebecca Bütof, Antje Dietrich
Published in: Biomedical Physics & Engineering Express, Issue 6/3, 2020, Page(s) 037003, ISSN 2057-1976
DOI: 10.1088/2057-1976/ab79f1

Clinically relevant nanodosimetric simulation of DNA damage complexity from photons and protons

Author(s): N. T. Henthorn, J. W. Warmenhoven, M. Sotiropoulos, A. H. Aitkenhead, E. A. K. Smith, S. P. Ingram, N. F. Kirkby, A. L. Chadwick, N. G. Burnet, R. I. Mackay, K. J. Kirkby, M. J. Merchant
Published in: RSC Advances, Issue 9/12, 2019, Page(s) 6845-6858, ISSN 2046-2069
DOI: 10.1039/c8ra10168j

Gold Nanopeanuts as Prospective Support for Cisplatin in Glioblastoma Nano-Chemo-Radiotherapy

Author(s): Joanna Depciuch, Justyna Miszczyk, Alexey Maximenko, Piotr M. Zielinski, Kamila Rawojć, Agnieszka Panek, Pawel Olko, Magdalena Parlinska-Wojtan
Published in: International Journal of Molecular Sciences, Issue 21/23, 2020, Page(s) 9082, ISSN 1422-0067
DOI: 10.3390/ijms21239082

Modeling Radioimmune Response—Current Status and Perspectives

Author(s): Thomas Friedrich, Nicholas Henthorn, Marco Durante
Published in: Frontiers in Oncology, Issue 11, 2021, ISSN 2234-943X
DOI: 10.3389/fonc.2021.647272

Commentary: RBE in proton therapy – where is the experimental in vivo data?

Author(s): Brita Singers Sørensen
Published in: Acta Oncologica, Issue 58/10, 2019, Page(s) 1337-1339, ISSN 0284-186X
DOI: 10.1080/0284186x.2019.1669819

Simultaneous Measurements of Dose and Microdosimetric Spectra in a Clinical Proton Beam Using a scCVD Diamond Membrane Microdosimeter

Author(s): Oluwasayo Loto, Izabella Zahradnik, Amelia Maia Leite, Ludovic De Marzi, Dominique Tromson, Michal Pomorski
Published in: Sensors, Issue 21/4, 2021, Page(s) 1314, ISSN 1424-8220
DOI: 10.3390/s21041314

Proton beam therapy: perspectives on the National Health Service England clinical service and research programme

Author(s): Neil G Burnet, Ranald I Mackay, Ed Smith, Amy L Chadwick, Gillian A Whitfield, David J Thomson, Matthew Lowe, Norman F Kirkby, Adrian M Crellin, Karen J Kirkby
Published in: The British Journal of Radiology, Issue 93/1107, 2020, Page(s) 20190873, ISSN 0007-1285
DOI: 10.1259/bjr.20190873

Spatial correlation of linear energy transfer and relative biological effectiveness with suspected treatment‐related toxicities following proton therapy for intracranial tumors

Author(s): Jakob Ödén, Iuliana Toma‐Dasu, Petra Witt Nyström, Erik Traneus, Alexandru Dasu
Published in: Medical Physics, Issue 47/2, 2020, Page(s) 342-351, ISSN 0094-2405
DOI: 10.1002/mp.13911

Biomedical Research Programs at Present and Future High-Energy Particle Accelerators

Author(s): Vincenzo Patera, Yolanda Prezado, Faical Azaiez, Giuseppe Battistoni, Diego Bettoni, Sytze Brandenburg, Aleksandr Bugay, Giacomo Cuttone, Denis Dauvergne, Gilles de France, Christian Graeff, Thomas Haberer, Taku Inaniwa, Sebastien Incerti, Elena Nasonova, Alahari Navin, Marco Pullia, Sandro Rossi, Charlot Vandevoorde, Marco Durante
Published in: Frontiers in Physics, Issue 8, 2020, ISSN 2296-424X
DOI: 10.3389/fphy.2020.00380

Hi-C implementation of genome structure for in silico models of radiation-induced DNA damage

Author(s): Samuel P. Ingram, Nicholas T. Henthorn, John W. Warmenhoven, Norman F. Kirkby, Ranald I. Mackay, Karen J. Kirkby, Michael J. Merchant
Published in: PLOS Computational Biology, Issue 16/12, 2020, Page(s) e1008476, ISSN 1553-7358
DOI: 10.1371/journal.pcbi.1008476

RBE for proton radiation therapy – a Nordic view in the international perspective

Author(s): Iuliana Toma-Dasu, Alexandru Dasu, Anne Vestergaard, Petra Witt Nyström, Håkan Nyström
Published in: Acta Oncologica, Issue 59/10, 2020, Page(s) 1151-1156, ISSN 0284-186X
DOI: 10.1080/0284186x.2020.1826573

Predicting late magnetic resonance image changes in glioma patients after proton therapy

Author(s): J. Eulitz, E.G.C. Troost, F. Raschke, E. Schulz, B. Lutz, A. Dutz, S. Löck, P. Wohlfahrt, W. Enghardt, C. Karpowitz, M. Krause, A. Lühr
Published in: Acta Oncologica, Issue 58/10, 2019, Page(s) 1536-1539, ISSN 0284-186X
DOI: 10.1080/0284186x.2019.1631477

Mapping the Future of Particle Radiobiology in Europe: The INSPIRE Project

Author(s): Nicholas T. Henthorn, Olga Sokol, Marco Durante, Ludovic De Marzi, Frederic Pouzoulet, Justyna Miszczyk, Pawel Olko, Sytze Brandenburg, Marc Jan van Goethem, Lara Barazzuol, Makbule Tambas, Johannes A. Langendijk, Marie Davídková, Vladimír Vondráĉek, Elisabeth Bodenstein, Joerg Pawelke, Antony J. Lomax, Damien C. Weber, Alexandru Dasu, Bo Stenerlöw, Per R. Poulsen, Brita S. Sørensen, Cai Gr
Published in: Frontiers in Physics, Issue 8, 2020, ISSN 2296-424X
DOI: 10.3389/fphy.2020.565055

Determining the parameter space for effective oxygen depletion for FLASH radiation therapy

Author(s): B C Rothwell, N F Kirkby, M J Merchant, A L Chadwick, M Lowe, R I Mackay, J H Hendry, K J Kirkby
Published in: Physics in Medicine & Biology, Issue 66/5, 2021, Page(s) 055020, ISSN 0031-9155
DOI: 10.1088/1361-6560/abe2ea

Comparative Proton and Photon Irradiation Combined with Pharmacological Inhibitors in 3D Pancreatic Cancer Cultures

Author(s): Josephine Görte, Elke Beyreuther, Erik H. J. Danen, Nils Cordes
Published in: Cancers, Issue 12/11, 2020, Page(s) 3216, ISSN 2072-6694
DOI: 10.3390/cancers12113216

Harnessing radiation to improve immunotherapy: better with particles?

Author(s): Marco Durante, Silvia Formenti
Published in: The British Journal of Radiology, Issue 93/1107, 2020, Page(s) 20190224, ISSN 0007-1285
DOI: 10.1259/bjr.20190224

Applying Tissue Slice Culture in Cancer Research—Insights from Preclinical Proton Radiotherapy

Author(s): Theresa Suckert, Treewut Rassamegevanon, Johannes Müller, Antje Dietrich, Antonia Graja, Michael Reiche, Steffen Löck, Mechthild Krause, Elke Beyreuther, Cläre von Neubeck
Published in: Cancers, Issue 12/6, 2020, Page(s) 1589, ISSN 2072-6694
DOI: 10.3390/cancers12061589

Hibernation and Radioprotection: Gene Expression in the Liver and Testicle of Rats Irradiated under Synthetic Torpor

Author(s): Walter Tinganelli, Timna Hitrec, Fabrizio Romani, Palma Simoniello, Fabio Squarcio, Agnese Stanzani, Emiliana Piscitiello, Valentina Marchesano, Marco Luppi, Maximiliano Sioli, Alexander Helm, Gaetano Compagnone, Alessio Morganti, Roberto Amici, Matteo Negrini, Antonio Zoccoli, Marco Durante, Matteo Cerri
Published in: International Journal of Molecular Sciences, Issue 20/2, 2019, Page(s) 352, ISSN 1422-0067
DOI: 10.3390/ijms20020352

In Vitro Comparison of Passive and Active Clinical Proton Beams

Author(s): Anna Michaelidesová, Jana Vachelová, Jana Klementová, Tomáš Urban, Kateřina Pachnerová Brabcová, Stanislav Kaczor, Martin Falk, Iva Falková, Daniel Depeš, Vladimír Vondráček, Marie Davídková
Published in: International Journal of Molecular Sciences, Issue 21/16, 2020, Page(s) 5650, ISSN 1422-0067
DOI: 10.3390/ijms21165650

Virus Irradiation and COVID-19 Disease

Author(s): Marco Durante, Kai Schulze, Sebastien Incerti, Ziad Francis, Sara Zein, Carlos Alberto Guzmán
Published in: Frontiers in Physics, Issue 8, 2020, ISSN 2296-424X
DOI: 10.3389/fphy.2020.565861

Harnessing radiation to improve immunotherapy: better with particles?

Author(s): Marco Durante, Silvia Formenti
Published in: The British Journal of Radiology, 2019, Page(s) 20190224, ISSN 0007-1285
DOI: 10.1259/bjr.20190224

Hibernation and Radioprotection: Gene Expression in the Liver and Testicle of Rats Irradiated under Synthetic Torpor

Author(s): Walter Tinganelli, Timna Hitrec, Fabrizio Romani, Palma Simoniello, Fabio Squarcio, Agnese Stanzani, Emiliana Piscitiello, Valentina Marchesano, Marco Luppi, Maximiliano Sioli, Alexander Helm, Gaetano Compagnone, Alessio Morganti, Roberto Amici, Matteo Negrini, Antonio Zoccoli, Marco Durante, Matteo Cerri
Published in: International Journal of Molecular Sciences, Issue 20/2, 2019, Page(s) 352, ISSN 1422-0067
DOI: 10.3390/ijms20020352

Simulation and experimental validation of a prototype electron beam linear accelerator for preclinical studies

Author(s): Pierre Lansonneur, Vincent Favaudon, Sophie Heinrich, Charles Fouillade, Pierre Verrelle, Ludovic De Marzi
Published in: Physica Medica, Issue 60, 2019, Page(s) 50-57, ISSN 1120-1797
DOI: 10.1016/j.ejmp.2019.03.016

Experimental characterisation of a proton kernel model for pencil beam scanning techniques

Author(s): L. De Marzi, A. Da Fonseca, C. Moignier, A. Patriarca, F. Goudjil, A. Mazal, I. Buvat, J. Hérault
Published in: Physica Medica, Issue 64, 2019, Page(s) 195-203, ISSN 1120-1797
DOI: 10.1016/j.ejmp.2019.07.013

Optimal reference genes for normalization of qPCR gene expression data from proton and photon irradiated dermal fibroblasts

Author(s): Steffen Nielsen, Niels Bassler, Leszek Grzanka, Jan Swakon, Pawel Olko, Christian Nicolaj Andreassen, Jan Alsner, Brita Singers Sørensen
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
DOI: 10.1038/s41598-018-30946-0

A New Standard DNA Damage (SDD) Data Format

Author(s): J. Schuemann, A. L. McNamara, J. W. Warmenhoven, N. T. Henthorn, K. J. Kirkby, M. J. Merchant, S. Ingram, H. Paganetti, K. D. Held, J. Ramos-Mendez, B. Faddegon, J. Perl, D. T. Goodhead, I. Plante, H. Rabus, H. Nettelbeck, W. Friedland, P. Kundrát, A. Ottolenghi, G. Baiocco, S. Barbieri, M. Dingfelder, S. Incerti, C. Villagrasa, M. Bueno, M. A. Bernal, S. Guatelli, D. Sakata, J. M. C. Brown, Z. F
Published in: Radiation Research, Issue 191/1, 2019, Page(s) 76, ISSN 0033-7587
DOI: 10.1667/rr15209.1

Clinically relevant nanodosimetric simulation of DNA damage complexity from photons and protons

Author(s): N. T. Henthorn, J. W. Warmenhoven, M. Sotiropoulos, A. H. Aitkenhead, E. A. K. Smith, S. P. Ingram, N. F. Kirkby, A. L. Chadwick, N. G. Burnet, R. I. Mackay, K. J. Kirkby, M. J. Merchant
Published in: RSC Advances, Issue 9/12, 2019, Page(s) 6845-6858, ISSN 2046-2069
DOI: 10.1039/c8ra10168j

Advanced Sandwich Composite Cores for Patient Support in Advanced Clinical Imaging and Oncology Treatment

Author(s): Robert H. Morris, Nicasio R. Geraldi, Lucy C. Pike, Jörg Pawelke, Aswin L. Hoffmann, Nicola Doy, Johanna L. Stafford, Abi Spicer, Michael I. Newton
Published in: Materials, Issue 13/16, 2020, Page(s) 3549, ISSN 1996-1944
DOI: 10.3390/ma13163549

Uncertainty of RBE Model in Proton Radiotherapy Based on $\frac {\alpha }{\beta }$ Ratio and Linear Energy Transfer

Author(s): K. Jeleń, L. Grzanka, P. Olko
Published in: Acta Physica Polonica B, Issue 51/1, 2020, Page(s) 405, ISSN 0587-4254
DOI: 10.5506/aphyspolb.51.405

Water Equivalence of Various 3D Printed Materials for Proton Therapy --- Monte Carlo Simulation, Treatment Planning Modelling and Validation by Measurements

Author(s): A. Wochnik, J. Swakoń, P. Olko
Published in: Acta Physica Polonica B, Issue 51/1, 2020, Page(s) 409, ISSN 0587-4254
DOI: 10.5506/aphyspolb.51.409

Out-of-field doses for scanning proton radiotherapy of shallowly located paediatric tumours—a comparison of range shifter and 3D printed compensator

Author(s): A Wochnik, L Stolarczyk, I Ambrožová, M Davídková, M De Saint-Hubert, S Domański, C Domingo, Ž Knežević, R Kopeć, M Kuć, M Majer, N Mojżeszek, V Mares, I Martínez-Rovira, M Á Caballero-Pacheco, E Pyszka, J Swakoń, S Trinkl, M Tisi, R Harrison, P Olko
Published in: Physics in Medicine & Biology, Issue 66/3, 2021, Page(s) 035012, ISSN 0031-9155
DOI: 10.1088/1361-6560/abcb1f

Beam Monitor Calibration for Radiobiological Experiments With Scanned High Energy Heavy Ion Beams at FAIR

Author(s): Francesca Luoni; Francesca Luoni; Uli Weber; Daria Boscolo; Marco Durante; Marco Durante; Claire-Anne Reidel; Claire-Anne Reidel; Christoph Schuy; Klemens Zink; Klemens Zink; Felix Horst; Felix Horst
Published in: Frontiers in physics 8, 568145 (2020). doi:10.3389/fphy.2020.568145, Issue 13, 2020, ISSN 2296-424X
DOI: 10.15120/gsi-2020-01146

Particle therapy in Europe

Author(s): Cai Grau, Marco Durante, Dietmar Georg, Johannes A. Langendijk, Damien C. Weber
Published in: Molecular Oncology, Issue 14/7, 2020, Page(s) 1492-1499, ISSN 1574-7891
DOI: 10.1002/1878-0261.12677

OC-0563 First experience with the model-based selection of head and neck cancer patients for proton therapy

Author(s): M. Tambas, H.P. Van der Laan, J.G.M. Van den Hoek, H.P. Bijl, M. Dieters, R.G.J. Kierkels, D. Scandurra, S. Both, R.J.H.M. Steenbakkers, J.A. Langendijk
Published in: Radiotherapy and Oncology, Issue 133, 2019, Page(s) S293-S294, ISSN 0167-8140
DOI: 10.1016/s0167-8140(19)30983-1

Influence of Therapeutic Proton Beam on Glioblastoma Multiforme Proliferation Index — A Preliminary Study

Author(s): A.M. Bogdali-Suślik, K. Rawojć, J. Miszczyk, A. Panek, M. Woźniak, K. Szewczyk, T. Książek, M. Bik-Multanowski, J. Swakoń, W. Komenda, N. Mojżeszek, T. Kajdrowicz, R. Kopeć, P. Olko
Published in: Acta Physica Polonica A, Issue 137/1, 2020, Page(s) 64-69, ISSN 0587-4246
DOI: 10.12693/aphyspola.137.64

Evolution of the hypoxic compartment on sequential oxygen partial pressure maps during radiochemotherapy in advanced head and neck cancer

Author(s): Marta Lazzeroni, Ana Ureba, Nicole Wiedenmann, Nils H. Nicolay, Michael Mix, Benedikt Thomann, Dimos Baltas, Iuliana Toma-Dasu, Anca L. Grosu
Published in: Physics and Imaging in Radiation Oncology, Issue 17, 2021, Page(s) 100-105, ISSN 2405-6316
DOI: 10.1016/j.phro.2021.01.011

First experience with model-based selection of head and neck cancer patients for proton therapy

Author(s): Makbule Tambas, Roel J.H.M. Steenbakkers, Hans P. van der Laan, Atje M. Wolters, Roel G.J. Kierkels, Dan Scandurra, Erik W. Korevaar, Edwin Oldehinkel, Tineke W.H. van Zon-Meijer, Stefan Both, Johanna G.M. van den Hoek, Johannes A. Langendijk
Published in: Radiotherapy and Oncology, Issue 151, 2020, Page(s) 206-213, ISSN 0167-8140
DOI: 10.1016/j.radonc.2020.07.056

Towards FLASH proton therapy: the impact of treatment planning and machine characteristics on achievable dose rates

Author(s): Steven van de Water, Sairos Safai, Jacobus M. Schippers, Damien C. Weber, Antony J. Lomax
Published in: Acta Oncologica, Issue 58/10, 2019, Page(s) 1463-1469, ISSN 0284-186X
DOI: 10.1080/0284186x.2019.1627416

Insights into the non-homologous end joining pathway and double strand break end mobility provided by mechanistic in silico modelling

Author(s): John W. Warmenhoven, Nicholas T. Henthorn, Samuel P. Ingram, Amy L. Chadwick, Marios Sotiropoulos, Nickolay Korabel, Sergei Fedotov, Ranald I. Mackay, Karen J. Kirkby, Michael J. Merchant
Published in: DNA Repair, Issue 85, 2020, Page(s) 102743, ISSN 1568-7864
DOI: 10.1016/j.dnarep.2019.102743

In Silico Models of DNA Damage and Repair in Proton Treatment Planning: A Proof of Concept

Author(s): Edward A. K. Smith, N. T. Henthorn, J. W. Warmenhoven, S. P. Ingram, A. H. Aitkenhead, J. C. Richardson, P. Sitch, A. L. Chadwick, T. S. A. Underwood, M. J. Merchant, N. G. Burnet, N. F. Kirkby, K. J. Kirkby, R. I. Mackay
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
DOI: 10.1038/s41598-019-56258-5

The Effect of Ionizing Radiation on MCF-7 Breast Cancer Cell Line

Author(s): Agnė Bartnykaitė, Rasa Ugenskienė, Arturas Inčiūra, Elona Juozaitytė
Published in: 2020

Patient-specific 3D printed compensators for proton pencil beam scanning of shallow situated tumours

Author(s): A. Wochnik, T. Kajdrowicz, J. Swakoń, E. Kieres, W. Komenda, R. Kopeć, D. Krzempek, M. Liszka, B. Michalec, G. Mierzwińska, A. Pędracka, M. Rydygier, K. Skowrońska, U. Sowa, P. Wrzesińska and P. Olko
Published in: 2018

Optimization of Preselection Process in Model-based Selection for Proton Therapy in Head & Neck Cancer

Author(s): M. Tambas, J.G.M. van den Hoek, R.G.J. Kierkels, D. Scandurra, A.M. Wolters, D. Mulder, E. Oldehinkel, T. van Zon-Meijer, S. Both, R.J.H.M. Steenbakkers, J.A. Langendijk
Published in: ESTRO2020, 2020

Modelling framework for FMISO and FDG PET imaging tailored dose prescription

Author(s): M. Lazzeroni, A. Ureba, D. Baltas, A. L. Grosu, I. Toma-Dasu
Published in: ESTRO38, 2019

"Cell responses to Ionizing Radiation: Current Research at Lithuanian University of Health Sciences and Future Perspectives with ""Inspire"" Project"

Author(s): Elona Juozaityte, Agne Bartnykaite, Rasa Ugenskiene, Danguole Laukaitiene
Published in: Knowledge for Use in Practice, 2019, Page(s) 100 p.

OC-0563 First experience with the model-based selection of head and neck cancer patients for proton therapy

Author(s): M. Tambas, H.P. Van der Laan, J.G.M. Van den Hoek, H.P. Bijl, M. Dieters, R.G.J. Kierkels, D. Scandurra, S. Both, R.J.H.M. Steenbakkers, J.A. Langendijk
Published in: Radiotherapy and Oncology, Issue 133, 2019, Page(s) S293-S294, ISSN 0167-8140
DOI: 10.1016/s0167-8140(19)30983-1

Preselection Tool for the Model-Based Selection of Head and Neck Cancer Patients for Proton Therapy

Author(s): M. Tambas, H.P. van der Laan, A.V.D. Hoek, H.P. Bijl, M. Dieters, D. Scandurra, S. Both, R. Steenbakkers, J.A. Langendijk
Published in: International Journal of Radiation Oncology*Biology*Physics, Issue 105/1, 2019, Page(s) E384, ISSN 0360-3016
DOI: 10.1016/j.ijrobp.2019.06.1647

Dosimetry of primary beam and scattered radiation in proton therapy

Author(s): Pawel Olko
Published in: IFJ Pan, 2020

Does FLASH deplete Oxygen? Experimental Evaluation for Photons, Protons and Carbon Ions

Author(s): Jansen, Jeannette; Knoll, Jan; Beyreuther, Elke; Pawelke, Jörg; Skuza, Raphael; Hanley, Rachel; Brons, Stephan; Pagliari, Francesca; Seco, Joao
Published in: Issue 3, 2021

Using Comprehensive Relative-Biological-Effectiveness Simulations to Assess the Potential Clinical Gain of FLASH Proton Therapy

Author(s): S van de Water, S Fabiano, N Bizzocchi, S Safai, D Weber, A Mazal, J Unkelbach, A Lomax
Published in: 2020 Joint APPM/Comp Meeting, 2020

Assessment of the Probability of Tumour Control for Prescribed Doses Based on Imaging of Oxygen Partial Pressure

Author(s): Ana Ureba, Emely Kjellsson Lindblom, Iuliana Toma-Dasu, Alexandru Dasu, Marta Lazzeroni
Published in: Oxygen Transport to Tissue XLII, Issue 1269, 2021, Page(s) 185-190
DOI: 10.1007/978-3-030-48238-1_29

Cell responses to ionizing radiation: current research at Lithuania University of Health Sciences and future perspectives with “Inspire” project

Author(s): Juozaitytė, Elona;Bartnykaitė, Agnė;Laukaitienė, Danguolė;Ugenskienė, Rasa
Published in: Rīga Stradiņš University International conference on Medical and Health Care Sciences, Issue Knowledge for Use in Practice: abstracts, 2019, Page(s) Conference Section Oncology and Haematology

Cellular response to proton radiation.

Author(s): Anna Michaelidesová
Published in: 2018

Towards incorporation of RBE uncertainty in proton therapy planning systems

Author(s): Leszek Grzanka , Kinga Jeleń, Michael P.R. Waligórski
Published in: 2019