Objective
Orthopaedic and dental implants are commonly used clinically. Their success rely on adequate primary and secondary stabilities, the latter being achieved through osseointegration, where bone grows around and onto the surface of the implant. However, prosthesis anchorage failures are still experienced and remain difficult to anticipate. The biomechanical properties of the bone-implant interface are the essentials for determining the implant stability but are still poorly understood. The objective of BOMB is to better understand the multiscale evolution of the biomechanical properties of the bone-implant interface with the overall aim to improve the long-term stability of implants. The project will use and further develop a standardized implant model of the host team to limit the influence of the implant geometry on osseointegration. Animal experimentation on rabbit and sheep will enable to work in a controlled as well as enhanced environments, using bone marrow stem cells, which are thought to be a promising new therapeutic tool to boost implant integration and hence improve implant stability. BOMB will combine the latest and advanced multimodal techniques spanning the nano and micro-scale to explore the structural and mechanical properties of the interface on a same sample. For instance, neutron high-resolution micro-tomography, a technique adapted to the presence of metallic components, has barely been applied on bone and will enable investigation of the microstructural properties of the interface. A successful completion of BOMB would represent a major step forward our limited understanding of the bone-implant biomechanical behaviour. This will lead to the development of new models, regenerative strategies as well as new implants to improve dental and orthopaedics solutions, and contribute to an increase of the life span of prostheses to ensure patients comfort and restoration of their daily life activity.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine odontology dental implantology
- medical and health sciences medical biotechnology cells technologies stem cells
- natural sciences mathematics pure mathematics geometry
- medical and health sciences clinical medicine orthopaedics
- medical and health sciences medical biotechnology implants
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2017
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75794 Paris
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.