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Active Pharmaceutical Production in Flow

Descripción del proyecto

Un programa de formación en investigación para la producción mediante química de flujo

La fabricación de productos farmacéuticos y de química fina emplea operaciones por lotes, dado que muchas síntesis eficaces requieren reactivos y condiciones que son demasiado peligrosas como para poder modificar su escala. La operación continua permite el uso de reactores más pequeños a escala industrial, lo cual minimiza los riesgos asociados a condiciones peligrosas. El proyecto APPFlow, financiado por las Acciones Marie Skłodowska-Curie, pretende desarrollar procesos más seguros y más eficaces para la fabricación de productos químicos. El objetivo es utilizar una plataforma innovadora de investigación para la formación de investigadores noveles en el ámbito de la química de flujo aplicada a la industria de los productos farmacéuticos y de química fina. Los investigadores noveles trabajarán en laboratorios universitarios e industriales, además de adquirir una serie de experiencias y formaciones únicas.

Objetivo

APPFlow will develop Early Stage Researchers (ESRs) in innovative research through a focussed training plan centred on flow chemistry, essential for the pharmaceutical and fine chemical industries in Europe. The training programme and research proposed in APPFlow tackles the problems associated with the production of advanced intermediates en-route to Active Pharmaceutical Ingredients (APIs) in the pharma-industry. The proposal is aligned with important European research goals outlined in Horizon 2020. Specifically, this research will address areas related to Resource Efficiency, Health, Environment and Nanotechnology. The end goals align with those of the SPIRE 2030 targets and aims, most closely aligned with the goal of ‘a reduction of up to 20% in non-renewable, primary raw material intensity compared to current levels by 2030.’ It comprises of three training sites located in Ireland (1) and the UK (2) and involves multidisciplinary collaboration between academic and industrial partners, each with complementary expertise across a range of disciplines. The programme will train 3 ESRs who will gain state-of-the-art, transferable knowledge in a number of valuable areas such as organic chemistry, catalytic chemistry, chemical engineering, process design and economics. APPFlow will establish long-term collaborations and develop structured research and training relevant to industry and academia and result in highly trained and employable ESRs. At the end of the APPFlow programme, the ESRs will possess a multidimensional perspective to research, enabling them to address problems with a holistic approach. The ESRs will also develop a range of transferable “soft” managerial skills that will widen their potential career opportunities and ability to contribute to a range of different sectors. For example, they will receive business and entrepreneurship mentoring, which will assist them in becoming future business leaders.

Coordinador

THE QUEEN'S UNIVERSITY OF BELFAST
Aportación neta de la UEn
€ 909 517,68
Dirección
UNIVERSITY ROAD LANYON BUILDING
BT7 1NN Belfast
Reino Unido

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Región
Northern Ireland Northern Ireland Belfast
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
€ 909 517,68

Participantes (1)

Socios (1)