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Gut OncoMicrobiome Signatures (GOMS) associated with cancer incidence, prognosis and prediction of treatment response.

Deliverables

Communication plan and website

Communication plan and website

Epidemiological analysis

Epidemiological analysis of main flaws in data interpretation

Standardization of shotgun microbiome analysis

A detailed technical description of standardization of shotgun microbiome analysis on the unified database

Searching for OpenAIRE data...

Publications

At the forefront of the sequencing revolution—notes from the RNGS19 conference

Author(s): Sander Wuyts, Nicola Segata
Published in: Genome Biology, Issue 20/1, 2019, ISSN 1474-760X
DOI: 10.1186/s13059-019-1714-3

The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations

Author(s): Adrian Tett, Kun D. Huang, Francesco Asnicar, Hannah Fehlner-Peach, Edoardo Pasolli, Nicolai Karcher, Federica Armanini, Paolo Manghi, Kevin Bonham, Moreno Zolfo, Francesca De Filippis, Cara Magnabosco, Richard Bonneau, John Lusingu, John Amuasi, Karl Reinhard, Thomas Rattei, Fredrik Boulund, Lars Engstrand, Albert Zink, Maria Carmen Collado, Dan R. Littman, Daniel Eibach, Danilo Ercolini, Omar Ro
Published in: Cell Host & Microbe, Issue 26/5, 2019, Page(s) 666-679.e7, ISSN 1931-3128
DOI: 10.1016/j.chom.2019.08.018

Multiple levels of the unknown in microbiome research

Author(s): Andrew Maltez Thomas, Nicola Segata
Published in: BMC Biology, Issue 17/1, 2019, ISSN 1741-7007
DOI: 10.1186/s12915-019-0667-z

Altered Fecal Small RNA Profiles in Colorectal Cancer Reflect Gut Microbiome Composition in Stool Samples

Author(s): Sonia Tarallo, Giulio Ferrero, Gaetano Gallo, Antonio Francavilla, Giuseppe Clerico, Alberto Realis Luc, Paolo Manghi, Andrew Maltez Thomas, Paolo Vineis, Nicola Segata, Barbara Pardini, Alessio Naccarati, Francesca Cordero
Published in: mSystems, Issue 4/5, 2019, ISSN 2379-5077
DOI: 10.1128/mSystems.00289-19

Detecting contamination in viromes using ViromeQC

Author(s): Moreno Zolfo, Federica Pinto, Francesco Asnicar, Paolo Manghi, Adrian Tett, Frederic D. Bushman, Nicola Segata
Published in: Nature Biotechnology, Issue 37/12, 2019, Page(s) 1408-1412, ISSN 1087-0156
DOI: 10.1038/s41587-019-0334-5

Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0

Author(s): Francesco Asnicar, Andrew Maltez Thomas, Francesco Beghini, Claudia Mengoni, Serena Manara, Paolo Manghi, Qiyun Zhu, Mattia Bolzan, Fabio Cumbo, Uyen May, Jon G. Sanders, Moreno Zolfo, Evguenia Kopylova, Edoardo Pasolli, Rob Knight, Siavash Mirarab, Curtis Huttenhower, Nicola Segata
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-16366-7

Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients

Author(s): Lisa Derosa, Bertrand Routy, Marine Fidelle, Valerio Iebba, Laurie Alla, Edoardo Pasolli, Nicola Segata, Aude Desnoyer, Filippo Pietrantonio, Gladys Ferrere, Jean-Eudes Fahrner, Emmanuelle Le Chatellier, Nicolas Pons, Nathalie Galleron, Hugo Roume, Connie P.M. Duong, Laura Mondragón, Kristina Iribarren, Mélodie Bonvalet, Safae Terrisse, Conrad Rauber, Anne-Gaëlle Goubet, Romain Daillère, Fabie
Published in: European Urology, Issue 78/2, 2020, Page(s) 195-206, ISSN 0302-2838
DOI: 10.1016/j.eururo.2020.04.044

A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies

Author(s): Dita Gudra, Saeed Shoaie, Davids Fridmanis, Janis Klovins, Hugo Wefer, Ivars Silamikelis, Raitis Peculis, Ineta Kalnina, Ilze Elbere, Ilze Radovica-Spalvina, Rolf Hultcrantz, Ģirts Šķenders, Marcis Leja, Lars Engstrand
Published in: Gut, Issue 68/9, 2019, Page(s) 1723-1725, ISSN 0017-5749
DOI: 10.1136/gutjnl-2018-316225

A Pilot Low-Inflammatory Dietary Intervention to Reduce Inflammation and Improve Quality of Life in Patients With Familial Adenomatous Polyposis: Protocol Description and Preliminary Results

Author(s): Patrizia Pasanisi, Manuela Gariboldi, Paolo Verderio, Stefano Signoroni, Andrea Mancini, Licia Rivoltini, Massimo Milione, Enzo Masci, Chiara Maura Ciniselli, Eleonora Bruno, Alessandra Macciotta, Antonino Belfiore, Maria Teresa Ricci, Giuliana Gargano, Daniele Morelli, Giovanni Apolone, Marco Vitellaro
Published in: Integrative Cancer Therapies, Issue 18, 2019, Page(s) 153473541984640, ISSN 1534-7354
DOI: 10.1177/1534735419846400

Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

Author(s): Maria Paula Roberti, Satoru Yonekura, Connie P. M. Duong, Marion Picard, Gladys Ferrere, Maryam Tidjani Alou, Conrad Rauber, Valerio Iebba, Christian H. K. Lehmann, Lukas Amon, Diana Dudziak, Lisa Derosa, Bertrand Routy, Caroline Flament, Corentin Richard, Romain Daillère, Aurélie Fluckiger, Isabelle Van Seuningen, Mathias Chamaillard, Audrey Vincent, Stephanie Kourula, Paule Opolon, Pierre Ly,
Published in: Nature Medicine, Issue 26/6, 2020, Page(s) 919-931, ISSN 1078-8956
DOI: 10.1038/s41591-020-0882-8

Trial watch : the gut microbiota as a tool to boost the clinical efficacy of anticancer immunotherapy

Author(s): Romain Daillère, Lisa Derosa, Mélodie Bonvalet, Nicola Segata, Bertrand Routy, Manuela Gariboldi, Eva Budinská, I. Jolanda M. De Vries, Alessio Gordon Naccarati, Valérie Zitvogel, Carlos Caldas, Lars Engstrand, Sibylle Loilbl, Jacques Fieschi, Lucie Heinzerling, Guido Kroemer, Laurence Zitvogel
Published in: OncoImmunology, Issue 9/1, 2020, Page(s) 1774298, ISSN 2162-402X
DOI: 10.1080/2162402x.2020.1774298

Can we harness the microbiota to enhance the efficacy of cancer immunotherapy?

Author(s): B. Brett Finlay, Romina Goldszmid, Kenya Honda, Giorgio Trinchieri, Jennifer Wargo, Laurence Zitvogel
Published in: Nature Reviews Immunology, 2020, ISSN 1474-1733
DOI: 10.1038/s41577-020-0374-6

Immunostimulatory gut bacteria

Author(s): Laurence Zitvogel, Guido Kroemer
Published in: Science, Issue 366/6469, 2019, Page(s) 1077-1078, ISSN 0036-8075
DOI: 10.1126/science.aaz7595