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Elucidating the role of macrophages in liver regeneration and tissue unit formation

Project description

Cellular interplay during liver regeneration

The liver has a fundamental role in body homeostasis. Unlike any other organ, it exhibits an astounding capacity to regenerate upon injury and return to its prior size and weight. The EU-funded LiverMacRegenCircuit project is interested to delineate the role of resident and recruited macrophages in the process of liver regeneration. Researchers are working under the hypothesis that various cell types including macrophages and hepatocytes need to be replenished after injury. Investigation of the crosstalk between cell types and the signals required for maintaining the cell circuit will lead to a better understanding of the regeneration process and pave the way for regenerative interventions.

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Coordinator

VIB VZW
Net EU contribution
€ 166 320,00
Address
Rijvisschestraat 120
9052 Zwijnaarde - Gent
Belgium

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Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Research Organisations
Non-EU contribution
€ 0,00