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Implementation of Best Practice of Design Solid-State Power Amplifier for Developing New Generation PET Accelerators

Project description

Innovative particle accelerators in PET installations

Positron emission tomography (PET) is a nuclear medicine procedure that measures metabolic activity in cells of body tissues. PET is mostly used in patients with brain or heart conditions, cancer, and dementia. A cyclotron, which creates a strong electric field to accelerate particles producing radioisotopes, is an essential part of PET installation. The strong electric field is presently produced by a tetrode vacuum tube, an outdated technology which is increasingly expensive to use and maintain. Funded by the Marie Skłodowska-Curie Actions programme, the GreenSSPA project aims to develop a solid-state transistor-based technology to replace the vacuum tube in cyclotron installations, making those more reliable, affordable and accessible to the public.

Objective

According to WHO report, last updated on 2017, the rate of cancer and neurodegenerative diseases (e.g. Dementia, Alzheimer?s, and Parkinson?s disease) is rapidly increasing in both less and more developed countries. They reported that the number of people with Dementia in worldwide is projected to increase to nearly double and a half from 50 million in 2017 to 135.5 million in 2050 and also global cancer rate could increase by 50% to 15 million by 2020. Such reports are alarming scientists to enhance research domains on the diagnostic methods to identify as early as possible to improve levels of treatments. One of the best diagnostic methods for such diseases is to employ Positron Emission Tomography (PET) scanner. The PET scan technology has been under-researched and -developed for many years, and it is still ongoing updating. One of the major components of the PET scanner is cyclotron for accelerating particles. A cyclotron is the most sophisticated part of a PET installation. It makes a strong electric field to accelerate particles, results in radioisotopes. The strong electric field is usually made by a Klystron vacuum tube which is an expensive and immobile part. Hence, in hospital without a cyclotron and far away areas, it is a problem to deliver the radioactive material, as it has a short lifetime, half an hour to few hours and it costs quite a lot to ship the radioactive material by helicopter. In this project, we propose to be used solid-state technology instead of vacuum tube. It will make possible to realise a mobile and affordable cyclotron. Hence, more cyclotrons could be deployed even in remote areas, resulting a cheap and fast treatment. A high impact on both the scientific and industrial communities is predicted from the project. The project is naturally a multidisciplinary project while involving communication engineering, mechanic engineering, physics, and medical science. It is well suited with the selected research group of host organization.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

(opens in new window) H2020-MSCA-IF-2020

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Coordinator

UPPSALA UNIVERSITET
Net EU contribution
€ 203 852,16
Address
VON KRAEMERS ALLE 4
751 05 Uppsala
Sweden
Region
Östra Sverige Östra Mellansverige Uppsala län
Activity type
Higher or Secondary Education Establishments
Links
Total cost
€ 203 852,16