Objective
Nowadays, available surgical skin closure techniques still remain painful and are prone to infections. To assess these challenges, DAHAD aims to develop new hydrogels with a dual action: biological tissues adhesion and antibacterial activity. The hydrogels will be prepared by the gelation of biomimetic dendrimer-polymer hybrids in aqueous solutions. These hybrids will be composed of a central linear polymer, namely Pluronic® F-127, decorated at its extremities with multiple biomimetic catechol moieties to confer biological adhesive properties to the gels. The hydrogels will be loaded with diverse hydrophilic and lipophilic antibiotics to locally deliver them into the surgical site and prevent infections. DAHAD contemplates (i) the organic synthesis of the dendrimer-polymer hybrids, (ii) the hydrogels preparation and the study of their adhesiveness, physicochemical characterization and thermo-responsiveness (iii) the drug delivery of hydrophilic and lipophilic antibiotics throughout the hydrogels by direct diffusion or assisted by micellar nanoparticles and their skin biocompatibility (iv) and the back loop enhancement of the gelation abilities, adhesion and drug delivery results using hydrogen bonding (H-bonding) supramolecular chemistry.
DAHAD is built as a multidisciplinary and international project along which the Purdue University (USA), the Universidad de Zaragoza (Spain) and the Instituto de Nanociencia y Materiales de Aragón (Spain) will combine their efforts and expertise to pursue the planned R&I objectives, as well as the dissemination of the results to scientific, industrial and public audiences. It aims to boost the applicant’s career, to complement the expertise of INMA in biomaterials for medical applications and be the kick-starter of a solid, international and successful collaborative network.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences polymer sciences
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antibiotics
- engineering and technology nanotechnology nano-materials
- engineering and technology industrial biotechnology biomaterials
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-GF - HORIZON TMA MSCA Postdoctoral Fellowships - Global Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28006 Madrid
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.