Project description
Compact, dynamic and highly sensitive scintillating detectors for next-generation radiation therapy
Cancer is the second leading cause of death worldwide after heart disease, accounting for nearly one in six deaths in 2020. Despite significant advances, the detectors used in modern radiation therapy treatment face numerous technical and practical challenges that impede effective therapy and increase risks to patients. With the support of the Marie Skłodowska-Curie Actions programme, the X-MiND project will design and fabricate a novel extremely compact, real-time, dynamic and highly sensitive X-ray/H+ (proton) micro/nano scintillating detector to address these challenges. A nanometric scintillating detector targeting high-resolution local 2D chemical mapping of a material will also be demonstrated.
Objective
Modern radiation therapy treatment is driven by the everlasting demand for suitable detectors that can perform under different radiation beams (photon, proton, electron, ion, etc.) at small fields. The industrially developed dosimeter/detectors are still limited by the significant size requirement, volume averaging effect, lack of sensitivity, correction factors, and low signal-to-noise ratio, etc. Thus, quality treatment is still hampered and continues to risk the patients. In addition, scintillator-based X-ray cameras are still suffered from low compactness, modest response time, and crosstalk, which shows strong limitations in the existing technology. In this context, this research work is devoted to the design and fabrication of a novel extremely compact, real-time, dynamic, and highly sensitive X-ray/H+ Micro/Nano Scintillating Detector (X-MiND). The developed micro-detector will be tested for high-energy photon and particle beam characterizations along with simulation techniques. A multi-dosimeter system exploited from a bundle of single detectors will be realized and tested, targeting the next generation X-ray cameras.
Subsequently, a nanometric scintillating detector will be demonstrated in surface physics application in synchrotron targeting high-resolution local 2D chemical mapping of a material by employing a novel dual-probe technique.
Thus, the medical outcomes of this research will explore miniaturized dosimetry, exact dose verification in the small field that initiates early-stage tumor treatments and the first step of new generation X-ray cameras with improved performances. The physics outcomes are expected in the direct surface imaging of X-ray free-standing waves (XSW).
The new fundamental knowledge developed in this project could be applied to other multiple domains. From the project, I aim to improve my expertise by training-through-research with leading experts worldwide and bring this knowledge back to Europe to share and integrate me.
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CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors optical sensors
- natural sciences physical sciences theoretical physics particle physics photons
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Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-GF - HORIZON TMA MSCA Postdoctoral Fellowships - Global Fellowships
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Call for proposal
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(opens in new window) HORIZON-MSCA-2021-PF-01
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13284 Marseille
France
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