Objective
Label-free detection and discerning of single proteins is essential to reduce the impact of degenerative diseases (e.g. cancer) by its ultra-early detection as well as to expand our understanding on the processes taking place in living beings. The objective of this project is developing a new technique for the optomechanical label-free detection and characterization of single protein. The working principle of the proposed technique consist on illuminating a protein and transferring its photothermal heating to a suspended membrane on which it is adsorbed. This suspended membrane can mechanically oscillate in drum-like modes, so as the protein transfers its heat to the membrane, its mechanical properties will change, producing a shift in its resonance frequency. Therefore, tracking the resonance frequency as a function of the incident lights wavelength will allow discerning among different proteins by obtaining their absorption spectra.
On the other hand, PROPHOTOM will have a high impact on my career. Implemented at TU Delft and supervised by Prof. Peter G. Steeneken and Dr. Farbod Alijani, this project will allow introducing myself into new subjects which the supervisors master (2D materials and condensed matter physics). Furthermore, the supervisors will benefit from my wide expertise on mechanical resonators for the optical characterization of biological samples, which guarantees the two-way transfer of knowledge. In addition to the scientific training, this project will also provide me different non-scientific skills, increasing my competencies and employability while allowing me developing an international network.
Eventually, this project will contribute significantly to Europes economic and societal advance providing knowledge in different subjects (biophysics, biochemistry or medicine) and new technologies, contributing to the achievement of the UNs Sustainable Development Goals (SDG 3 & 9) and Horizon Europe Missions (HEM cancer).
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences clinical medicine oncology
- natural sciences biological sciences biophysics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
2628 CN Delft
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.