Project description
Fast biosensors for sepsis and infection diagnosis
Hundreds of thousands of people die from sepsis and bacterial infections every year. Although early and accurate diagnosis is critical, current methods can take days to deliver results. This delay contributes to the misuse of antimicrobial drugs, fuelling the global crisis of antibiotic resistance. With the support of the Marie Skłodowska-Curie Actions programme, the ECLectic project addresses this urgent need by developing next-generation biosensors based on electrochemiluminescence. The idea is to combine this technique that generates light through electrochemical reactions with nanostructured materials and microfluidic devices. The generated point-of-care tools will dramatically reduce diagnosis time to hours.
Objective
Sepsis and bacterial infections are leading causes of death in hospitals with more than 500 thousand casualties yearly. The early infection diagnosis as well as early microbial treatment are of great importance. However, effective treatment is hampered by misuse of antimicrobial drugs, leading to resistant bacterial pathogens, high risks of infection recurrence and patient mortality as well as increased medical costs. Thus, there is a need for fast and reliable sensors systems for diagnosis of sepsis reducing the time-to-report from several days or weeks to hours, facilitating the early delivery of appropriate anti- bacteria therapy.
ECLectic network will address the worldwide problem of sepsis and bacterial infection by developing the next generation of sensing platforms, providing entirely new diagnostic paradigms. ECLectic will develop, optimize, and assess novel biosensors based on electrochemiluminescence by combining different nano- and microstructured materials and fluidic devices. ECLectic will ultimately result in novel fast and reliable point-of-care devices with applications of bacterial infection analysis, monitoring of disease recurrence, and progression. It will close the gap between innovative research in the field of nanostructured materials and their application in biosensing technology.
ECLectic will create a Center of Excellence in Europe for the training of young researchers in the research and development of sensing platforms for bacterial infection and sepsis. By training, ECLectic will provide highly skilled European researchers for academic research in biodetection, materials, microfluidics and electrochemistry as well as for the European biosensor industry. ECLectic will generate a flexible cluster of excellent young researchers ready to tackle the European challenges in the development of novel detection platform for bacterial infection. They will be trained well to become leaders in industrial as well as academic research and development.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences classical mechanics fluid mechanics microfluidics
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- social sciences sociology demography mortality
- natural sciences biological sciences microbiology bacteriology
- engineering and technology nanotechnology nano-materials
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Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks
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Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-DN-01
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40126 Bologna
Italy
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Participants (9)
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20009 San Sebastian
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20122 Milano
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33000 Bordeaux
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9 Dublin
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5656 AE Eindhoven
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28040 Madrid
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48940 Leioa
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79106 Freiburg
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28359 Bremen
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Partners (9)
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98122 Messina
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06269 Storrs
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RG31 5AL Tilehurst
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06132 Perugia
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4001 Basel
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79098 Freiburg
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6708 PB Wageningen
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15001 La Coruna
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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48940 Leioa
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