Project description
Educating researchers about frailty for healthy ageing
Our society is ageing due to declining birth rates and longer life expectancy. While more people are living longer, the average adult spends the last 15-20 years in poor health. Frailty in old age contributes to this, increasing vulnerability to stressors like falls, surgeries, and infections. Consequently, there is a growing focus on improving the period of healthy living, known as healthspan. Supported by the Marie Skłodowska-Curie Actions programme, the UNION project will educate 13 early-stage researchers about frailty for healthy ageing. It involves experts from various disciplines and uses cutting-edge technologies applied to clinical settings. The project aims to address the challenges of our ageing society.
Objective
With falling birth rates and increasing life expectancy we are an ageing society. 20% of boys and 25% of girls born in 2019 are expected to reach their 100th birthday. This would be good news if it were not for the fact that healthy life span has not kept pace with increasing longevity and now on average adults spend the last 15-20 years of life in ill health. Frailty is a major component of ill health in old age and refers to an enhanced vulnerability to stressors, such as falls, surgery or infections, which was demonstrated clearly in the mortality data for the COVID19 pandemic. The transition from robust health to frailty is a critical factor in the loss of independence and places increased pressure on health and social care. All of this has led governments to prioritise the enhancement of healthspan.
The Doctorate Network on UnderstandiNg fraIlty tOwards a future of healthy ageiNg (UNION) is a multi-partner joint doctoral research training network with the overall aims of educating 13 Early Stage Researchers (DCs), advancing the current understanding of frailty, and providing innovative solutions on how healthy ageing can be achieved. UNION brings together world leaders in a range of relevant disciplines (frailty, ageing biology and ageing medicine, inflammation, immunosenescence, immunometabolism, stem cell biology) with state-of-the art technologies including mass spectrometry metabolomics, advanced imaging, artificial intelligence, CRISPR-CAS9 libraries, SPECTRA 35-colour flow cytometry, global and conditional knockout mice. This technological excellence is applied to the clinical situation through unique longitudinal human ageing and frailty cohorts, longitudinal assessment of age-related multimorbidity in animal models and innovative multidimensional frailty indices in humans. Together this integrated activity will provide the highest quality training and research environment in our rapidly ageing society.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences artificial intelligence
- social sciences sociology demography mortality
- medical and health sciences health sciences public health epidemiology pandemics
- natural sciences biological sciences cell biology
- medical and health sciences medical biotechnology cells technologies stem cells
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks
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Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2023-DN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
20122 Milano
Italy
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Participants (8)
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28049 Madrid
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20132 Milano
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20132 Milano
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171 77 STOCKHOLM
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28006 Madrid
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13125 Berlin
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Participation ended
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50937 Koeln
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50931 Koln
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Partners (14)
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8020 Graz
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14482 Potsdam
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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07981 Whippany
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1200 Bruxelles / Brussel
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9000 Ghent
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EC1V 2PT London
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88662 Ueberlingen
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28010 Madrid
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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WC1E 6BT London
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B15 2TT Birmingham
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50668 Köln
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73100 Lecce
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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10117 Berlin
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
50937 Koeln
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