Skip to main content
Go to the home page of the European Commission (opens in new window)
English en
CORDIS - EU research results
CORDIS

Metabolic disease heterogeneity definition, prevention and remission with targeted interventions

Objective

Obesity, diabetes and associated complications constitute a rapidly escalating scientific and societal challenge across Europe marked by profound heterogeneity in causes, clinical trajectories and treatment responses. This heterogeneity explains the limited effectiveness of standardized therapies and highlights the need to stratify metabolic disease. To confront this challenge, MEDIculous REMeDy brings together a pan-European, interdisciplinary doctoral network spanning academia, healthcare, industry, public and patient organizations. The network’s first objective is to train critical and entrepreneurial metabolic health researchers through innovative interdisciplinary, translational and intersectoral training focused on tailored career development, transferable skills and leadership. Gender-responsive research design, open science, public and patient engagement underpin this training culture, equipping DCs with essential skills for academic and non-academic careers. These early-career researchers will drive – and be shaped by – our scientific objectives: (1) to map metabolic disease heterogeneity across the full disease spectrum from early metabolic dysfunction and obesity to advanced diabetes with complications, and (2) to dissect this heterogeneity from underlying molecular mechanisms to biomarkers, therapeutic targets and treatment responses. To achieve its scientific objectives, the consortium will integrate metabolic medicine and computational systems biology that draw on multi-country European patient cohorts, advanced human in vitro platforms and complementary in vivo disease models. This novel integrative strategy enables the development of robust patient stratification and personalized therapeutic approaches applicable across European populations, pushing precision medicine forward. By uniting scientific excellence, pioneering training and societal relevance, MEDIculous REMeDy transforms metabolic disease research and precision medicine across Europe.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks

See all projects funded under this funding scheme

Call for proposal

(opens in new window) HORIZON-MSCA-2025-DN-01

See all projects funded under this call

Coordinator

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Net EU contribution
€ 580 544,64
Address
INGOLSTADTER LANDSTRASSE 1
85764 Neuherberg
Germany
Region
Bayern Oberbayern München, Landkreis
Activity type
Research Organisations
Links
Total cost
No data

Participants (11)

Partners (19)