Objective
Micro-organisms excrete low-molecular weight chelators, siderophores, in response to iron deficiency. Most siderophores are hexadentate ligands which form highly stable six-coordinate complexes with iron. In contrast the bis(catecholamide) siderophore N,N-(2,3-dihydroxybenzoyl)-L-lysine of Azotobacter vinelandii, is ideally suited for binding the four vacant coordination sites of MoO2 . The aim of this proposal is to determine the chemical design features which enable bis- and triscatecholate siderophores of A. vinelandii and their analogues to discriminate between Fe(III) and Mo(VI), to study the redox behaviour of these complexes, and to determine the role they play in the siderophore-mediated transport of Mo in A. vinelandii. This study of may lead to specific sensing applications, and to a better understanding of the chemistry underlying the initial biological transformations of Mo.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences inorganic chemistry transition metals
- natural sciences biological sciences biochemistry biomolecules
- natural sciences biological sciences microbiology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NR4 7UH Norwich
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.