Objective
Chlamydiae are obligate intracellular bacteria occupying a vesicle called an inclusion throughout their life cycle. They evade lysosome destruction by inhibiting fusion of the inclusion with lysosomes. There is very little information on the origin of the vacuolar membrane surrounding the chlamydiae or the properties of the compartment in which they proliferate. Additionally, little is known about the role of the cytoskeleton in chlamydiahost cell interaction. My proposed project concerns the intracellular survival of chlamydiae. The subcellular compartment(s) in which chlamydiae survive will be characterised by 1) following the distribution of specific intracellular organelle markers of the host cell in the chlamydiae compartment(s) and 2) measuring the pH of these vacuoles. In addition, the mechanism whereby chlamydiae avoid lysosomal destruction and the role of cytoskeletal elements in the formation of the chlamydia inclusion and the chlamydia infectious cycle will be investigated.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
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Coordinator
54006 Thessaloniki
Greece
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.