Objective Chronic immunopathologies constitute a major class of diseases with high morbidity and mortality for the patient. TAGAPO aims to improve the current state of the art in the understanding of aetiology, pathophysiology, progress and outcome of disease by using:1) conditional gene targeting in mice to study the impact of ablating specific cells, genes and pathways from animals developing specific immunopathologies;2) differential gene expression profiling using DNA array technologies on important cell types to discover new genes with putative involvement in immunity and immunopathology, and3) optimised technologies for conditional genome modification in the mouse to identify new gene function and relevance to immunity and disease. TAGAPO build up new knowledge into mechanisms of disease pathogenesis and aims to disclose new diagnostic markers and therapeutic targets for further academic, clinical and industrial exploitation. Fields of science social sciencessociologydemographymortalitynatural sciencesbiological sciencesgeneticsDNAmedical and health sciencesbasic medicinephysiologypathophysiologynatural sciencesbiological sciencesgeneticsgenomes Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator BIOMEDICAL SCIENCES RESEARCH CENTRE "ALEXANDER FLEMING" EU contribution No data Address Fleming Street 14-16 16672 GLYFADA (ATTIKI) Greece See on map Total cost No data Participants (9) Sort alphabetically Sort by EU Contribution Expand all Collapse all BIOXELL S.P.A. Italy EU contribution No data Address Via Olgettina 58 20132 MILANO See on map Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE France EU contribution No data Address Parc Scientifique et Technologique de Luminy 13288 MARSEILLE See on map Total cost No data EUROPEAN MOLECULAR BIOLOGY LABORATORY Italy EU contribution No data Address Via E. Ramarini 32 00016 MONTEROTONDO See on map Total cost No data GERMAN CANCER RESEARCH CENTER Germany EU contribution No data Address Im Neuenheimer Feld 280 69120 HEIDELBERG See on map Total cost No data INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution No data Address Parc Scientifique de Luminy 13288 MARSEILLE See on map Total cost No data INSTITUT PASTEUR France EU contribution No data Address Rue du Docteur Roux 25 75724 PARIS See on map Total cost No data UNIVERSITAET KOELN Germany EU contribution No data Address Carl-von-Linné-Weg 101 50829 Köln See on map Total cost No data UNIVERSITY OF ZURICH Switzerland EU contribution No data Address 71,Raemistrasse 71 CH-8091 ZURICH See on map Total cost No data UNIVERSITÀ DEGLI STUDI DI MILANO-BICOCCA Italy EU contribution No data Address Piazza della Scienza 2 20126 MILANO See on map Total cost No data
