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Content archived on 2024-05-24

Exploitation of dt40 cells to study the mechanism of immunoglobulin gene diversification

Objective

We will use the DT40 cell line to investigate the role of immunoglobulin specific transcription factors in targeting of hyper mutation, the mechanism of action of AID in controlling the process and the possible involvement of error prone polymerases.

Fields of science (EuroSciVoc)

Topic(s)

Data not available

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

MEDICAL RESEARCH COUNCIL
EU contribution
No data
Address
Hills Road
CB2 2QH CAMBRIDGE
United Kingdom
Total cost
No data