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Content archived on 2024-05-27

Role of the ph-domain in regulating pdk1 activity

Objective

I propose to generate a PDK1 knocking mouse embryonic stem cell line that expresses a mutated form of DKP1 which PH-domain can not interact with PtdIns (3,4,5)P3. The study of this cell line will permit to further understand the mechanism by which PtdIns(3,4,5)P_3 regulates the insulin signal transduction

Fields of science (EuroSciVoc)

Topic(s)

Data not available

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

UNIVERSITY OF DUNDEE
EU contribution
No data
Address
Nethergate
DD1 4HN DUNDEE
United Kingdom
Total cost
No data