Objetivo To understand the properties of complex systems, we currently lack a theoretical framework for the analysis of aggregate behaviour in multi-scale, multi-objective systems. GENNETEC gathers a consortium of computer scientists, physicists, biologists and bioinformaticists. It takes inspiration from a biological case (transcriptional interaction networks) that exemplifies many challenges in complex systems research, including elemental heterogeneity, interconnected scales in time and space, emergence of higher level behaviour, and hierarchies.GENNETEC will exploit its case study to build a theoretical framework for modelling/simulating complex systems and for the analysis of their emergent properties. This development will make use of methods from formal software engineering and from qualitative approaches in statistical physics. It will deal with the two-way information flow between two or more successive levels of model description, with particular attention on consequences for aggregate behaviour. To tackle complex systems with more modelling levels, hierarchies of descriptions will be studied.Winthin this theoretical framework we will develop bottom-up multi-scale methodologies to analyse global aggregation behaviours. Design of multi-stable systems will be handled using multi-objective optimization algorithms, borrowing from evolutionary computation and from message-passing techniques. These studies will be extended and generalized across other, non-biological applications to understand and design complex systems with desired aggregate behaviour, having both stability and versatility / adaptativity.The biological outcome of these studies will be transferred into a scalable sofware tool to achieve a breakthrough in the bioinformatics domain of inference in transcriptional interaction networks. GENNETEC will also deliver a software tool for modelling/simulating complex networks, as well as reports and publications on the above-described issues. Ámbito científico natural sciencescomputer and information sciencessoftware Programa(s) FP6-IST - Information Society Technologies: thematic priority under the specific programme "Integrating and strengthening the European research area" (2002-2006). Tema(s) IST-2005-2.3.4 (xi) - (xi) FET Proactive Initiative: Complex Systems Convocatoria de propuestas Data not available Régimen de financiación STREP - Specific Targeted Research Project Coordinador CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Aportación de la UE Sin datos Dirección 3, RUE MICHEL-ANGE PARIS CEDEX 16 Francia Ver en el mapa Coste total Sin datos Participantes (7) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo ABDUS SALAM INTERNATIONAL CENTER FOR THEORETICAL PHYSICS Italia Aportación de la UE Sin datos Dirección STRADA COSTIERA 11 34100 TRIESTE Ver en el mapa Coste total Sin datos FONDAZIONE ISTITUTO PER L'INTERSCAMBIO SCIENTIFICO Italia Aportación de la UE Sin datos Dirección VIALE SETTIMIO SEVERO 65 10133 TORINO Ver en el mapa Coste total Sin datos INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE Aportación de la UE Sin datos Dirección Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET EN AUTOMATIQUE Francia Aportación de la UE Sin datos Dirección DOMAINE DE VOLUCEAU 78153 LE CHESNAY Ver en el mapa Coste total Sin datos INSTITUTO SUPERIOR TECNICO Portugal Aportación de la UE Sin datos Dirección Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos NORAY BIOINFORMATICS, S.L. España Aportación de la UE Sin datos Dirección PARQUE TECNOLOGICO, 801A 48160 DERIO (BIZKAIA) Ver en el mapa Coste total Sin datos UNIVERSITE D'EVRY-VAL D'ESSONNE Francia Aportación de la UE Sin datos Dirección BOULEVARD FRANCOIS MITTERAND 23 91025 EVRY Ver en el mapa Coste total Sin datos
