Objective
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with an ever-increasing incidence in the aged population. However, there is no definitive diagnostic test for Alzheimer's disease. AD patients are only probably detected at a progressed stage of the disease when neurodegeneration already occurred and the possibilities of treatment are reduced. In the proposed project, the Medical University of Vienna in Austria and the diagnostic company Randox Laboratories Ltd. in the UK join their expertise to develop a blood test for AD with the potential scientific background that blood platelets mirror AD-related alteration of the central nervous system.
In a clinical study the University has already identified 21 new AD-specific platelet proteins by difference two dimensional gel electrophoresis (DIGE). The proposed project combines the brand-new CyDye DIGE proteomic method with innovative Protein Biochip Array Technology of the Company. It aims to develop a Biochip, which detects the AD-specific proteins in blood platelets. An intensive transfer of knowledge between the two partners is necessary to achieve this goal. Mutual exchange of researchers for two years would accelerate the development of a diagnostic AD Biochip. University researchers will participate in production of antibodies and in the setup of a Protein Biochip Array at the Company. Company's researchers will learn platelet preparation, evaluate antibodies and clinical evaluation of the experimental Biochips at the University.
This exchange of researchers will overcome the gap between academia and industry. The techniques developed in the course of this collaboration will open new possibilities, which go far beyond the proposed project. This includes analysis of platelets from patients with other diseases such as diabetes or cardiovascular disease as well as analysis of other blood cells. Thus, the proposed project will constitute the basis for lasting inter-sectorial research collaboration.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- medical and health sciences basic medicine neurology neurodegenerative diseases dementia alzheimer
- medical and health sciences clinical medicine endocrinology diabetes
- medical and health sciences clinical medicine cardiology cardiovascular diseases
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-3
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
VIENNA
Austria
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.