Objective There is a growing need for effective monitoring of the micro-organisms and bioprocesses used in the sustainable production of fuels, chemicals and pharmaceuticals. The NANOBE -consortium will develop a compact, flexible analysis tool for reaction monitoring applications in the industrial biotechnology industry. The result of the NANOBE –project will be an integrated measurement platform for real-time monitoring of industrial bioprocesses. This versatile platform will enable simultaneous analysis of dozens of analytes, including individual cells, product profiles and intracellular biomarkers. The platform will be composed of multiple 'lab-on-chip ' modules. Together, these modules will measure a broad range of analyte types, including small molecules, proteins, enzymes, metabolites, specific mRNAs and entire cells. The measurement platform will be a significant improvement in terms of automation, analysis time, identification and sensitivity. The analysis platform will permit real-time feedback control of large-scale production processes, screening of production organisms and optimisation of reaction conditions. The tool will improve process productivity, product quality and accelerate development of production organisms for applications in industrial biotechnology. The platform is designed to be flexible so that it can be applied either as a multiplex platform system to monitoring multiple analytes, or as individual device components for analysis of specific compounds. The versatile measurement tool will require only a change in method (e.g. a change of reagents or analysis conditions) to enable the measurement of a new analyte. The NANOBE consortium combines world-class expertise in microfluidics, nano- and microfabrication techniques, photonics, electronics, sensor technologies, and biotechnology. The platform will exploit the scaling laws associated with microfluidic devices to reduce analysis time and sample volume. Fields of science natural sciencesphysical sciencesclassical mechanicsfluid mechanicsmicrofluidicsengineering and technologyindustrial biotechnologyengineering and technologyother engineering and technologiesmicrotechnologylab on a chipengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsengineering and technologyenvironmental engineeringenergy and fuels Keywords ELISA bioprocess monitoring capillary electrophoresis cell analysis industrial bioprocess lab-on-chip mass spectrometry micro- and nanofabrication microfluidics on-line real-time Programme(s) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Topic(s) KBBE-2008-3-2-03 - Nanobiotechnology based biosensors for optimised bioprocesses Call for proposal FP7-KBBE-2008-2B See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator TEKNOLOGIAN TUTKIMUSKESKUS VTT EU contribution € 663 265,00 Address TEKNIIKANTIE 4 A 02044 VTT ESPOO Finland See on map Activity type Research Organisations Administrative Contact Päivi Heimala (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France EU contribution € 349 800,00 Address RUE MICHEL ANGE 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Gilles Pulvermuller (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE Switzerland EU contribution € 299 600,00 Address BATIMENT CE 3316 STATION 1 1015 Lausanne See on map Region Schweiz/Suisse/Svizzera Région lémanique Vaud Activity type Higher or Secondary Education Establishments Administrative Contact Philippe Renaud (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ALBERT-LUDWIGS-UNIVERSITAET FREIBURG Germany EU contribution € 365 144,00 Address FAHNENBERGPLATZ 79098 Freiburg See on map Region Baden-Württemberg Freiburg Freiburg im Breisgau, Stadtkreis Activity type Higher or Secondary Education Establishments Administrative Contact Melanie Baumann (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Institut für Bioprozess- und Analysenmesstechnik e.V. Germany EU contribution € 250 000,00 Address Rosenhof 1 37308 Heilbad Heiligenstadt See on map Activity type Research Organisations Administrative Contact Manfred Meister (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data PRESENS PRECISION SENSING GMBH Germany EU contribution € 300 400,00 Address AM BIOPARK 11 93053 Regensburg See on map Region Bayern Oberpfalz Regensburg, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Sebastian Basel (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data DIAGNOSWISS SA Switzerland EU contribution € 359 885,00 Address ZI LES ILETTES SECTEUR 4 1870 MONTHEY See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Frédéric Reymond (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data MICROSAIC SYSTEMS United Kingdom EU contribution € 359 998,00 Address Boundary Road GMS House GU215BX SURREY See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Malcolm Bateman (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data GALILAEUS OY Finland EU contribution € 46 990,00 Address KAIRISKULMANTIE 10 20781 Kaarina See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Kristiina Ylihonko (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
