Objective Microcantilever (MC) biosensors are innovative and versatile micro-electro-mechanical systems (MEMS). Due to (nano)mechanical transduction of biochemical reactions they allow sensitive, label-free, direct, real-time and multiplexed detection of molecules as well as specific investigations of molecular interactions and conformational changes. NASPE aims at generating the pre-requisites and supporting the effort to establish MC biosensors as a competitive technology in the field of drug screening by integrating skills and know-how of SMEs and RTD performers which cover leading positions in the fields featured by the project. NASPE outcomes are expected to enable the SMEs to strengthen their position in the international market of drug discovery, to gain access to new market segments and to create new highly skilled jobs in Europe. On the other hand, NASPE research activities will contribute to address inherent fundamental issues of MEMS biosensors, including functionalization, manufacturing and novel applications. The primary aim of NASPE is structured into the following SMART objectives: - Functionalization protocols for silicon and plastic MCs, necessary for performing molecular recognition experiments by MCs. They will be accomplished by months 9 and 18, respectively, and tested on conventional fluorescent essays. - Proof-of-concept of nanomechanical drug screening by MCs, that is the necessary step for designing MC essays. Experiments for silicon and plastic MCs will be assessed and statistically validated by month 12 and month 21, respectively. - Prototype plastic MC arrays, that will be provided by month 15 and tested against commercial silicon MCs. Plastic MCs are expected to have lower cost and enhanced performances with respect to silicon MCs. - “Field” test of MC drug screening and design of drug discovery kits, that is the ultimate project objective. MC costs/benefits will be benchmarked against the commercially available drug discovery essays. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoveryengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensorshumanitieslanguages and literatureliterature studiesliterary genresessaysnatural scienceschemical sciencesinorganic chemistrymetalloids Programme(s) FP7-SME - Specific Programme "Capacities": Research for the benefit of SMEs Topic(s) SME-1 - Research for SMEs Call for proposal FP7-SME-2007-1 See other projects for this call Funding Scheme BSG-SME - Research for SMEs Coordinator UNIVERSITA DEGLI STUDI DI BRESCIA EU contribution € 67 800,00 Address PIAZZA MERCATO 15 25121 Brescia Italy See on map Region Nord-Ovest Lombardia Brescia Activity type Higher or Secondary Education Establishments Administrative Contact Laura Eleonora Depero (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all CONCENTRIS GMBH Switzerland EU contribution € 208 000,00 Address Davidsbodenstrasse 63 4056 BASEL See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Urs Hubler (Dr.) Links Contact the organisation Opens in new window Total cost No data MS-Schramberg Micro GmbH & Co. KG Germany EU contribution € 17 500,00 Address Max-Planck-Str. 15 78713 Schramberg-Sulgen See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Armin Schaumann (Mr.) Links Contact the organisation Opens in new window Total cost No data NUREX s.r.l. Italy EU contribution € 159 500,00 Address LOCALITA SERRA LI LIONI 07100 SASSARI See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Franca Mannu (Dr.) Links Contact the organisation Opens in new window Total cost No data Airone Società Cooperativa Sociale ONLUS Italy EU contribution € 49 000,00 Address VIA CHICO MENDEZ 1 25030 ERBUSCO See on map Activity type Other Administrative Contact Angelo Di Gioia (Mr.) Links Contact the organisation Opens in new window Total cost No data FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV Germany EU contribution € 10 000,00 Address HANSASTRASSE 27C 80686 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Research Organisations Administrative Contact Andrea Zeumann (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CONSIGLIO NAZIONALE DELLE RICERCHE Italy EU contribution € 10 000,00 Address PIAZZALE ALDO MORO 7 00185 Roma See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Administrative Contact Giacomo Carrea (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Hans Heinlein Werkzeug-und Formenbau GmbH Germany EU contribution € 213 000,00 Address Angerzeile 1 90513 Zirndorf See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Hans Heinlein (Mr.) Links Contact the organisation Opens in new window Total cost No data
