Objective
Bone fractures represent a major health problem in the increasingly elder population. The correct prediction of bone fracture risk in bone disease, e.g. osteoporosis, is a mandatory issue for the prevention of traumatic events and related medical efforts. The assessment of the fracture risk is based on the clinical evaluation of bone mineral density, but with an estimation error ranging from 20% to 40%. Trabecular structure is known to play an important role in the mechanical behaviour of bone, but clinical imaging does not provide sufficient information. In order to perform a systematic and in depth analysis of the trabecular framework, and its relation with the mechanical properties, micro-tomographic devices are required. Using these devices, structural analysis of bone specimens could be performed by investigating the structure of the broken region, in order to examine the differences between broken and unbroken regions on specimens that were mechanically tested. The aim of the proposed project is the development of a system that will permit the prediction of in-vitro trabecular mechanical behaviour with possible applications on clinical meso-level x-ray images. The presented system will be comprised mainly of a classifier that will identify the fracture probability of bones’ regions using estimated mechanical parameters. In order to define the classifier, a fracture identification module, based on image processing, will be also developed with the aim to locate firstly broken and unbroken regions of mechanically tested specimens, and then estimate specific mechanical parameters related to the different regions. This initial knowledge will be used to train the classifier and to predict the broken region of not tested bone specimens.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2009-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
106 82 ATHINA
Greece
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.