Objective
Cancer treatment and vaccine development represent two of the major challenges that contemporary medicine is confronted with. Although significant progress has been achieved in both fields, the present methodologies remain limited, in part due to the numerous specific requirements for each treatment. This proposal focuses on the development of a novel, versatile drug delivery system suitable for either purpose, combining multifunctionality and controlled molecular release using biocompatible materials. The proposed approach involves the use of self-assembled nanocarriers based on amphiphilic DNA block copolymers with a photodegradable linker (PL) as a junction point (DNA-PL-Pol). These nanocarriers combine the advantageous features of the constituents of the DNA-PL-Pol, i.e. the possibility of attaching multiple functionalities by DNA hybridization, the localized and controlled release of encapsulants by near-infrared irradiation (NIR) and the biodegradability of the polymers. The project involves on one hand the synthesis of DNA-PL-Pol and the study of their aggregation behavior and on the other hand, the testing of the systems in cancer treatment and vaccine development. The proposed work will cover diverse fields in scientific research, i.e. organic and polymer synthesis, physical organic chemistry, supramolecular chemistry, biochemistry, cancer therapy and immunology.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences organic chemistry
- natural sciences biological sciences genetics DNA
- medical and health sciences basic medicine immunology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- medical and health sciences clinical medicine oncology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2010-IOF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1015 Lausanne
Switzerland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.