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Content archived on 2024-05-21

Platelet diagnostics

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European database for newborn disease

Neonatal alloimmune thrombosytopaenia (NAIT) is a disease where the newborn has a low platelet count. Software has been developed to store and analyse data from NAIT clinical databases.

As a result of difference in platelet types between the mother and baby, the neonate can suffer from a low platelet count due to destruction by the mother's antibodies. This can cause brain damage with consequent associated health challenges for the lifetime of the affected child. To assist in the drive to prevent this disease, the project consortium collaborated with Dendrite, a computing company. The aim was to devise software for the compilation and analysis of data collected from both the original database and clinical samples. The resulting package consists of a clinical outcomes database management system which provides data that is medically and biologically meaningful. The user can obtain an advance analysis of any surgical procedure based on related clinical data. The system is highly flexible and draws on the vast customisable database. The extensive range of analyses includes comprehensive probability outcomes, forecasts from tests including distribution and longitudinal analyses, and sequential and volume outcome analyses. The software also encompasses algorithms for risk assessment modelling tools. Project partners are seeking to expand the clinical and biological libraries and are extending their contacts across Europe to improve diagnostic features of this service.

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