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Smart integrated biodiagnostic systems for healthcare

Objective

Driven by clinical applications and MNT and IST technology, SmartHEALTH will develop an open integrated architecture for new biodiagnostic systems to support European companies exploiting bioassays or new application concepts. Initial system has a disposable fluidic cartridge with a desktop basestation linking to the ambient eHealth environment - health cards, patient data, online services. This concept will be miniaturised and cost engineered into a portable and consumer product. It will perform multianalyate sensing and interpretation, for nucleic acids, proteins and others and will handle multiple biological sample types.

Results will be interpreted and presented using bioinformatics. Systems will be healthcare user identity and ambient environment aware, respecting confidentiality and information access rights. The IP will enable enhanced medical diagnosis, leading to earlier and more precise results contributing to an increased quality of life as well as increasing the competitiveness of the European IVD sector. The IP will include: selection of probes, sample preparation, fluid handling, concentration, filtering; sensors and transducers, (label free systems and rapid nucleic acid detection systems); surface modification/integration of nanoscale elements; system development - controllers, actuators, data processing, communications and integration with ambient intelligence, on-line information services; understanding of fit to healthcare, input to medical management - user factors, costs, approvals, regulations, ethics.

Clinical areas are in Cancer Diagnostics - breast cancer recurrence monitoring, cervical cancer case finding, colorectal cancer - diagnostic/theranostic/prognostics. Each application includes clinical validation and commercial exploitation partners. The consortium is a powerful set of 3 Universities, 9 Research Institutions, 10 SMEs, 4 larger Companies and 4 Clinical Groups covering all the relevant issues.

Funding Scheme

IP - Integrated Project

Coordinator

THE UNIVERSITY OF NEWCASTLE UPON TYNE
Address
6 Kensington Terrace
NE1 7RU Newcastle Upon Tyne
United Kingdom

Participants (30)

CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT
Switzerland
Address
Rue Jaquet-droz 1
2007 Neuchatel
CHARITE-UNIVERSITATSMEDIZIN BERLIN
Germany
Address
Schumannstrasse 20
10117 Berlin
DUBLIN CITY UNIVERSITY
Ireland
Address

Glasnevin, Dublin 9
FORSCHUNGSZENTRUM KARLSRUHE GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG
Germany
Address
Weberstrasse 5
76133 Karlsruhe
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
Address
Hansastrasse 27C
80686 Muenchen
FRIEDRICH-SCHILLER-UNIVERSITAET JENA
Germany
Address
Fuerstengraben 1
07743 Jena
FUJIREBIO DIAGNOSTICS AB
Sweden
Address
Majnabbeterminalen
41455 Goteborg
FUNDACION GAIKER
Spain
Address
Parque Tecnologico De Zamudio, Edificio 202
48170 Zamudio
FUNDACION VASCA DE INNOVACION E INVESTIGACION SANITARIAS
Spain
Address
Plaza Asua 1
48150 Sondika
HOSPITAL DE CRUCES
Spain
Address
Plaza De Cruces S/n
48903 Cruces/barakaldo
HOSPITAL DONOSTIA
Spain
Address
Begiristain Pasalekua 107-115
20014 Donostia - San Sebastian
IKERLAN S. COOP
Spain
Address
Paseo J.m. Arizmendiarrieta 2
20500 Arrasate - Mondragon
INSTITUT FUER MIKROTECHNIK MAINZ GMBH
Germany
Address
Carl-zeiss-strasse 18-20
55129 Mainz
INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM VZW
Belgium
Address
Kapeldreef 75
3001 Leuven
IXSCIENT LIMITED
United Kingdom
Address
76 Popes Grove
TW1 4JX Twickenham Middlesex
MICROFLUIDIC CHIPSHOP GMBH
Germany
Address
Carl-zeiss-promenade 10
07745 Jena
MINIFAB (AUST) PTY LTD
Australia
Address
1 Dalmore Drive
3179 Scoresby, Victoria
MULTID ANALYSES AB
Sweden
Address
Lotsgatan 5 A
414 58 Goteborg
NETHERLANDS ORGANISATION FOR APPLIED SCIENTIFIC RESEARCH - TNO
Netherlands
Address
Schoemakerstraat 97
2628 VK Delft
OLIVETTI I - JET S.P.A.
Italy
Address
Localita Le Vieux
11020 Arnad
OSAKIDETZA
Spain
Address
Araba 45
01006 Vitoria - Gasteiz
SINTEF - STIFTELSEN FOR INDUSTRIELL OG TEKNISK FORSKNING VED NORGES TEKNISKE HOEGSKOLE
Norway
Address
Strindveien 4
7465 Trondheim
TATAA BIOCENTER AB
Sweden
Address
Sahlgrenska Science Park, Medicinaregatan 8 A
413 46 Goteborg
TELECOM ITALIA SPA
Italy
Address
Piazza Degli Affari 2
20123 Milano
THE NEXUS ASSOCIATION
Switzerland
Address
Rue Jaquet-droz 1, C/o Csem
2007 Neuchatel
UNDEFINED
Address
Undefined
Undefined
UNIVERSIDAD ROVIRA I VIRGILI
Spain
Address
Carrer De Escorxador S/n
43003 Tarragona
UNIVERSITÀ DEGLI STUDI DI TRENTO
Italy
Address
Via Belenzani 12
Trento
WTC, WICHT TECHNOLOGIE CONSULTING - DR. HENNING WICHT
Germany
Address
Frauenplatz 5
80331 Muenchen
ZARLINK SEMICONDUCTOR LIMITED
United Kingdom
Address
Cheney Manor
SN2 2QW Swindon, Wiltshireswindon Wiltshire