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ALGAE4IBD –FROM NATURE TO BEDSIDE- ALGAE BASED BIO COMPOUND FOR PREVENTION AND TREATMENT OF INFLAMMATION, PAIN AND IBD

Description du projet

Immersion profonde pour trouver des algues anti-inflammatoires

Et si la solution à une maladie chronique se trouvait dans nos océans, nos rivières ou nos lacs? Le projet Algae4IBD, financé par l’UE, répondra à cette question. Étudiant les composants des micro- et macroalgues marines et d’eau douce du laboratoire/pilote à l’échelle du marché, le projet cherchera de manière exhaustive des solutions pour transformer les ressources biologiques naturelles aquatiques en composants actifs sur le plan biologique afin de prévenir et traiter la maladie inflammatoire chronique de l’intestin (MICI). Plus particulièrement, il développera des composants à base d’algues tout en préservant leur biodiversité grâce à des technologies de culture et d’extraction révolutionnaires. Algae4IBD propose des solutions innovantes pour utiliser de manière durable des produits à base d’algues ayant une meilleure qualité nutritionnelle pour améliorer l’état de patients atteints de MICI.

Objectif

Algae4IBD's mission is to develop commercial products for Inflammatory Bowel Disease (IBD) prevention and treatment using aquatic natural biological resources. With the emerging developments in natural product, notable success has been achieved in discovering natural products and their synthetic structural analogues with anti-inflammatory activity. However, global biodiversity remains a largely unexploited resource for natural bioactive molecules with an enormous potential for developing commercial products with public health benefits. Micro and macroalgae, found in marine and freshwater, have been identified as promising sources of bioactive compounds including small molecules and secondary metabolites with a wide range of bioactivities as an antioxidant, anti-inflammatory and cancer preventive. Consumption of algae could, therefore, provide defence against chronic inflammatory diseases such as IBD, that until date have no effective cure. This project offers nature to bedside approach, using an entire development along the value chain for a new biodiscovery therapeutic approach by developing and examining algae-based compounds for IBD patients while guaranteeing algae's biodiversity preservation. We propose innovative solutions for increasing the use of algae-based ingredients and to ensure the science-based improvement of nutritional quality and its effect on public health. The researchers, companies and hospitals involved in the different stages of the project will use the biodiversity of algae, both micro and macro, as a wide source for bioactive compounds using state-of-the-art cultivation and extraction technologies for obtaining sufficient amounts of the bio-active molecules together with novel processing protocols. It will result in novel algal-based, high-quality bioactive compounds at GMP grade and lower costs for dual purposes – IBD prevention and treatment in relevance to the food as well as the pharmaceutical industries.

Appel à propositions

H2020-FNR-2020

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Sous appel

H2020-FNR-2020-2

Coordinateur

MIGAL GALILEE RESEARCH INSTITUTE LTD
Contribution nette de l'UE
€ 895 219,74
Adresse
SOUTH INDUSTRIAL ZONE
11016 KIRYAT SHEMONA
Israël

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Liens
Coût total
€ 895 222,50

Participants (23)