Weight Maintenance by AgRP neurons

Project Information

Yoyo-LepReSens

Grant agreement ID: 101002247

DOI 10.3030/101002247

EC signature date 30 April 2021

Start date 1 September 2021

End date 31 August 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 999 976,00

EU contribution € 1 999 976,00

Coordinated by

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo

Author(s): Konxhe Kulaj, Alexandra Harger, Michaela Bauer, Özüm S. Caliskan, Tilak Kumar Gupta, Dapi Menglin Chiang, Edward Milbank, Josefine Reber, Angelos Karlas, Petra Kotzbeck, David N. Sailer, Francesco Volta, Dominik Lutter, Sneha Prakash, Juliane Merl-Pham, Vasilis Ntziachristos, Hans Hauner, Michael W. Pfaffl, Matthias H. Tschöp, Timo D. Müller, Stefanie M. Hauck, Benjamin D. Engel, Jantje M. Ger
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-36148-1

HDAC5 controls a hypothalamic STAT5b-TH axis, the sympathetic activation of ATP-consuming futile cycles and adult-onset obesity in male mice

Author(s): Raian E. Contreras, Tim Gruber, Ismael González-García, Sonja C. Schriever, Meri De Angelis, Noemi Mallet, Miriam Bernecker, Beata Legutko, Dhiraj Kabra, Mathias Schmidt, Matthias H. Tschöp, Ruth Gutierrez-Aguilar, Jane Mellor, Cristina García-Cáceres, Paul T. Pfluger
Published in: Molecular Metabolism, Issue 90, 2024, Page(s) 102033, ISSN 2212-8778
Publisher: Elsevier GmbH
DOI: 10.1016/j.molmet.2024.102033

Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice

Author(s): Seun Akindehin, Arkadiusz Liskiewicz, Daniela Liskiewicz, Miriam Bernecker, Cristina Garcia-Caceres, Daniel J Drucker, Brian Finan, Gerald Grandl, Robert Gutgesell, Susanna M Hofmann, Ahmed Khalil, Xue Liu, Perla Cota, Mostafa Bakhti, Oliver Czarnecki, Aimée Bastidas-Ponce, Heiko Lickert, Lingru Kang, Gandhari Maity, Aaron Novikoff, Sebastian Parlee, Ekta Pathak, Sonja C Schriever, Michael Sterr,
Published in: Molecular Metabolism, 2023, ISSN 2212-8778
Publisher: Elsevier GmbH
DOI: 10.1016/j.molmet.2024.101915

Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1

Author(s): Ismael González-García, Elena García-Clavé, Alberto Cebrian-Serrano, Ophélia Le Thuc, Raian E. Contreras, Yanjun Xu, Tim Gruber, Sonja C. Schriever, Beata Legutko, Jutta Lintelmann, Jerzy Adamski, Wolfgang Wurst, Timo D. Müller, Stephen C. Woods, Paul T. Pfluger, Matthias H. Tschöp, Alexandre Fisette, Cristina García-Cáceres
Published in: Cell Metabolism, 2023, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2023.02.004