Somatic and Germline Mechanisms of Small RNA Inheritance

Project description

Transgenerational inheritance of small RNA molecules

Recent evidence challenges the concept that genetic material is the sole basis of biological inheritance. In addition to DNA, other molecules can also be passed down through generations, but the precise mechanism is unknown. The EU-funded RNAiNHERITANCE project focuses on the inheritance of small RNA molecules which have a known role in gene regulation. Researchers will use the nematode Caenorhabditis elegans as a model organism to study how small RNA molecules are transmitted from somatic cells to the germline and therefore to the next generation. Particular emphasis will be placed on the epigenetic inheritance of developmental processes.

Fields of science

• natural sciences › biological sciences › genetics › RNA
• natural sciences › biological sciences › genetics › genomes
• natural sciences › biological sciences › genetics › epigenetics

Programme(s)

• H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme

Topic(s)

• ERC-2020-COG - ERC CONSOLIDATOR GRANTS

Call for proposal

ERC-2020-COG

See other projects for this call

Funding Scheme

ERC-COG - Consolidator Grant

Host institution

INSTITUT PASTEUR

Net EU contribution

€ 1 997 150,00

Address

Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
France

Region

Ile-de-France › Ile-de-France › Paris

Activity type

Research Organisations

Links

Other funding

€ 1 997 150,00

Beneficiaries (1)

INSTITUT PASTEUR

France

Net EU contribution

€ 1 997 150,00

Address

Rue Du Docteur Roux 25-28
75724 Paris Cedex 15

Region

Ile-de-France › Ile-de-France › Paris

Activity type

Research Organisations

Links

Other funding

€ 1 997 150,00