Engineering Extracellular Matrices for Controlling Structure and Dynamics of Lipid Bilayer Membranes

Project description

Insight into cell membrane dynamics

The cell membrane facilitates fundamental biological processes including endocytosis, cell–cell communication and cell division. Therefore, understanding the factors that control membrane structure and dynamics can help modulate these processes. Unlike most approaches that alter lipid bilayer composition to impact membrane fluidity and stiffness, the EU-funded EXTREME project proposes to regulate cell membrane dynamics via engineering a complex extracellular microenvironment. The interdisciplinary nature of the project will provide unprecedented knowledge on cell membranes and pave the way for the development of novel therapies against membrane-associated diseases, such as type-2 diabetes, cancer and Alzheimer's disease.

Fields of science

• medical and health sciences › basic medicine › neurology › dementia › alzheimer
• medical and health sciences › clinical medicine › endocrinology › diabetes
• natural sciences › biological sciences › biochemistry › biomolecules › lipids
• medical and health sciences › clinical medicine › oncology
• natural sciences › biological sciences › biochemistry › biomolecules › proteins › enzymes

Programme(s)

• H2020-EU.4. - SPREADING EXCELLENCE AND WIDENING PARTICIPATION Main Programme

Topic(s)

• WF-02-2019 - Widening Fellowships

Call for proposal

H2020-WF-2018-2020

See other projects for this call

Sub call

H2020-WF-02-2019

Funding Scheme

MSCA-IF-EF-RI - RI – Reintegration panel

Coordinator

KOC UNIVERSITY

Net EU contribution

€ 145 355,52

Address

Rumeli Feneri Yolu Sariyer
34450 Istanbul
Türkiye

Region

İstanbul › İstanbul › İstanbul

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00