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Engineering Extracellular Matrices for Controlling Structure and Dynamics of Lipid Bilayer Membranes

Project description

Insight into cell membrane dynamics

The cell membrane facilitates fundamental biological processes including endocytosis, cell–cell communication and cell division. Therefore, understanding the factors that control membrane structure and dynamics can help modulate these processes. Unlike most approaches that alter lipid bilayer composition to impact membrane fluidity and stiffness, the EU-funded EXTREME project proposes to regulate cell membrane dynamics via engineering a complex extracellular microenvironment. The interdisciplinary nature of the project will provide unprecedented knowledge on cell membranes and pave the way for the development of novel therapies against membrane-associated diseases, such as type-2 diabetes, cancer and Alzheimer's disease.

Field of science

  • /natural sciences/biological sciences/biochemistry/biomolecules/lipids

Call for proposal

H2020-WF-02-2019
See other projects for this call

Funding Scheme

MSCA-IF-EF-RI - RI – Reintegration panel

Coordinator

KOC UNIVERSITY
Address
Rumeli Feneri Yolu Sariyer
34450 Istanbul
Turkey
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 145 355,52