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Rapid therapy development through Open nCoronavirus Vaccine Platform

Project description

A DNA vaccine platform against SARS-CoV-2

Accumulating genetic evidence on the new SARS-CoV-2 virus shows that its envelope and receptor binding domain only share 75 % homology with other human coronaviruses. This indicates that existing immunotherapies and vaccine candidates against other coronaviruses will probably not work against SARS-CoV-2. To generate and select the most potent candidates that protect against SARS-CoV-2 infection, the EU-funded OPENCORONA project will use a DNA vaccine platform. The most promising leads will initially be validated in animal models of coronavirus infection and then tested in a phase I clinical trial for safety in healthy volunteers.

Field of science

  • /medical and health sciences/basic medicine/pharmacology and pharmacy/pharmaceutical drug
  • /medical and health sciences/health sciences/infectious disease/RNA virus/coronavirus
  • /medical and health sciences/basic medicine/immunology/immunotherapy

Call for proposal

H2020-SC1-PHE-CORONAVIRUS-2020
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

KAROLINSKA INSTITUTET
Address
Nobels Vag 5
17177 Stockholm
Sweden
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 400 000

Participants (6)

JUSTUS-LIEBIG-UNIVERSITAET GIESSEN
Germany
EU contribution
€ 200 000
Address
Ludwigstrasse 23
35390 Giessen
Activity type
Higher or Secondary Education Establishments
FOLKHALSOMYNDIGHETEN
Sweden
EU contribution
€ 400 000
Address
Nobels Vag 18
171 82 Solna
Activity type
Other
IGEA SPA
Italy
EU contribution
€ 200 000
Address
Via Parmenide 10A
41012 Carpi Mo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
COBRA BIOPHARMA MATFORS AB
Sweden
EU contribution
€ 1 200 000
Address
Box 219
864 23 Matfors
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ADLEGO BIOMEDICAL AB
Sweden
EU contribution
€ 200 000
Address
Box 42
751 03 Uppsala
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
REGION STOCKHOLM
Sweden
EU contribution
€ 400 000
Address
Hantverkargatan 45
104 22 Stockholm
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)