Deliverables Open Research Data Pilot (2) Draft of Data Management Plan Description of datasets data sharing and archiving Updated version of Data Management Plan Websites, patent fillings, videos etc. (2) Project website and communication pack Project website and promotional tools for workshops and meetings Consortium secured intranet This tool will facilitate communication and establish the principles of work within the consortium Documents, reports (1) Communication and dissemination update This report will provide an update on the implementation and impact of the communication and dissemination activities Publications Peer reviewed articles (17) Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection Author(s): Vanessa Monteil, Matheus Dyczynski, Volker M Lauschke, Hyesoo Kwon, Gerald Wirnsberger, Sonia Youhanna, Haibo Zhang, Arthur S Slutsky, Carmen Hurtado del Pozo, Moritz Horn, Nuria Montserrat, Josef M Penninger, Ali Mirazimi Published in: EMBO Molecular Medicine, Issue 13/1, 2021, Page(s) 13:e13426, ISSN 1757-4676 Publisher: John Wiley & Sons Ltd. DOI: 10.15252/emmm.202013426 The Short- and Long-Range RNA-RNA Interactome of SARS-CoV-2 Author(s): Omer Ziv, Jonathan Price, Lyudmila Shalamova, Tsveta Kamenova, Ian Goodfellow, Friedemann Weber, Eric A. Miska Published in: Molecular Cell, Issue 80/6, 2020, Page(s) 1067-1077.e5, ISSN 1097-2765 Publisher: Cell Press DOI: 10.1016/j.molcel.2020.11.004 Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) is a host factor for RNA viruses including SARS-CoV-2 Author(s): Stephanie Devignot, Tim Wai Sha, Thomas Burkard, Patrick Schmerer, Astrid Hagelkruys, Ali Mirazimi, Ulrich Elling, Josef M. Penninger, Friedemann Weber Published in: BioRxiv, 2022, ISSN 2692-8205 Publisher: Cold Spring Harbor Laboratory, USA DOI: 10.1101/2022.02.17.480904 ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology Author(s): Gawish R, Starkl P, Pimenov L, Hladik A, Lakovits K, Oberndorfer F, Cronin SJ, Ohradanova-Repic A, Wirnsberger G, Agerer B, Endler L, Capraz T, Perthold JW, Cikes D, Koglgruber R, Hagelkruys A, Montserrat N, Mirazimi A, Boon L, Stockinger H, Bergthaler A, Oostenbrink C, Penninger JM, Knapp S. Published in: Elife, 2022, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.74623 Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level. Author(s): Zhu R, Canena D, Sikora M, Klausberger M, Seferovic H, Mehdipour AR, Hain L, Laurent E, Monteil V, Wirnsberger G, Wieneke R, Tampé R, Kienzl NF, Mach L, Mirazimi A, Oh YJ, Penninger JM, Hummer G, Hinterdorfer P. Published in: Nat Commun., 2022, Page(s) 2022 Dec 24;13(1):7926., ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-022-35641-3 Angiotensin-converting enzyme 2-at the heart of the COVID-19 pandemic Author(s): Oudit GY, Wang K, Viveiros A, Kellner MJ, Penninger JM. Published in: Cell, 2023, Page(s) 2023 Mar 2;186(5):906-922., ISSN 1097-4172 Publisher: Elsevier DOI: 10.1016/j.cell.2023.01.039 Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites Author(s): Hoffmann D, Mereiter S, Jin Oh Y, Monteil V, Elder E, Zhu R, Canena D, Hain L, Laurent E, Grünwald-Gruber C, Klausberger M, Jonsson G, Kellner MJ, Novatchkova M, Ticevic M, Chabloz A, Wirnsberger G, Hagelkruys A, Altmann F, Mach L, Stadlmann J, Oostenbrink C, Mirazimi A, Hinterdorfer P, Penninger JM. Published in: EMBO Journal, 2021, ISSN 0261-4189 Publisher: Nature Publishing Group DOI: 10.15252/embj.2021108375 Assessing kidney development and disease using kidney organoids and CRISPR engineering Author(s): Safi W; Marco A; Moya D; Prado P; Garreta E; Montserrat N Published in: Frontiers In Cell And Developmental Biology, 2022, ISSN 2296-634X Publisher: Frontiers Media Sa DOI: 10.3389/fcell.2022.948395 Protocol for SARS-CoV-2 infection of kidney organoids derived from human pluripotent stem cells Author(s): Garreta E, Moya-Rull D, Stanifer ML, Monteil V, Prado P, Marco A, Tarantino C, Gallo M, Jonsson G, Hagelkruys A, Mirazimi A, Boulant S, Penninger JM, Montserrat N. Published in: Star Protocols, 2022, ISSN 2666-1667 Publisher: Cell Press DOI: 10.1016/j.xpro.2022.101872 Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor Author(s): Capraz T, Kienzl NF, Laurent E, Perthold JW, Föderl-Höbenreich E, Grünwald-Gruber C, Maresch D, Monteil V, Niederhöfer J, Wirnsberger G, Mirazimi A, Zatloukal K, Mach L, Penninger JM, Oostenbrink C, Stadlmann J. Published in: Elife, 2021, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.73641 Human recombinant soluble ACE2 in severe COVID-19 Author(s): Alexander Zoufaly, Marko Poglitsch, Judith H Aberle, Wolfgang Hoepler, Tamara Seitz, Marianna Traugott, Alexander Grieb, Erich Pawelka, Hermann Laferl, Christoph Wenisch, Stephanie Neuhold, Doris Haider, Karin Stiasny, Andreas Bergthaler, Elisabeth Puchhammer-Stoeckl, Ali Mirazimi, Nuria Montserrat, Haibo Zhang, Arthur S Slutsky, Josef M Penninger Published in: The Lancet Respiratory Medicine, Issue 8/11, 2020, Page(s) 1154-1158, ISSN 2213-2600 Publisher: Elsevier Limited DOI: 10.1016/s2213-2600(20)30418-5 A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo. Author(s): Chan JF, Oh YJ, Yuan S, Chu H, Yeung ML, Canena D, Chan CC, Poon VK, Chan CC, Zhang AJ, Cai JP, Ye ZW, Wen L, Yuen TT, Chik KK, Shuai H, Wang Y, Hou Y, Luo C, Chan WM, Qin Z, Sit KY, Au WK, Legendre M, Zhu R, Hain L, Seferovic H, Tampé R, To KK, Chan KH, Thomas DG, Klausberger M, Xu C, Moon JJ, Stadlmann J, Penninger JM, Oostenbrink C, Hinterdorfer P, Yuen KY, Markovitz DM. Published in: Cell Rep Med, 2022, Page(s) 2022 Oct 18;3(10):100774., ISSN 2666-3791 Publisher: Cell Press DOI: 10.1016/j.xcrm.2022.100774 Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants Author(s): Monteil V, Eaton B, Postnikova E, Murphy M, Braunsfeld B, Crozier I, Kricek F, Niederhöfer J, Schwarzböck A, Breid H, Devignot S, Klingström J, Thålin C, Kellner MJ, Christ W, Havervall S, Mereiter S, Knapp S, Sanchez Jimenez A, Bugajska-Schretter A, Dohnal A, Ruf C, Gugenberger R, Hagelkruys A, Montserrat N, Kozieradzki I, Hasan Ali O, Stadlmann J, Holbrook MR, Schmaljohn C, Oostenbrink C, Sh Published in: EMBO Mol Med., Issue 17574676, 2022, ISSN 1757-4676 Publisher: John Wiley & Sons Ltd. DOI: 10.15252/emmm.202115230 Development of an aerosol intervention for COVID-19 disease: Tolerability of soluble ACE2 (APN01) administered via nebulizer. Author(s): Shoemaker RH, Panettieri RA Jr, Libutti SK, Hochster HS, Watts NR, Wingfield PT, Starkl P, Pimenov L, Gawish R, Hladik A, Knapp S, Boring D, White JM, Lawrence Q, Boone J, Marshall JD, Matthews RL, Cholewa BD, Richig JW, Chen BT, McCormick DL, Gugensberger R, Höller S, Penninger JM, Wirnsberger G. Published in: PLoS One, 2022, Page(s) 2022 Jul 11;17(7):e0271066. , ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0271066 Omicron variant of SARS-CoV-2 exhibits an increased resilience to the antiviral type I interferon response Author(s): Lyudmila Shalamova, Ulrike Felgenhauer, Jochen Wilhelm, Andreas R Schaubmar, Kathrin Büttner, Andreas Schoen, Marek Widera, Sandra Ciesek, Friedemann Weber Published in: PNAS Nexus, 2022, ISSN 2752-6542 Publisher: Oxford University Press DOI: 10.1093/pnasnexus/pgac067 A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells Author(s): Garreta E, Prado P, Stanifer ML, Monteil V, Marco A, Ullate-Agote A, Moya-Rull D, Vilas-Zornoza A, Tarantino C, Romero JP, Jonsson G, Oria R, Leopoldi A, Hagelkruys A, Gallo M, González F, Domingo-Pedrol P, Gavaldà A, Del Pozo CH, Hasan Ali O, Ventura-Aguiar P, Campistol JM, Prosper F, Mirazimi A, Boulant S, Penninger JM, Montserrat N. Published in: Cell Metab., 2022, ISSN 1550-4131 Publisher: Cell Press DOI: 10.1016/j.cmet.2022.04.009 Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19. Author(s): Sinnberg T, Lichtensteiger C, Ali OH, Pop OT, Jochum AK, Risch L, Brugger SD, Velic A, Bomze D, Kohler P, Vernazza P, Albrich WC, Kahlert CR, Abdou MT, Wyss N, Hofmeister K, Niessner H, Zinner C, Gilardi M, Tzankov A, Röcken M, Dulovic A, Shambat SM, Ruetalo N, Buehler PK, Scheier TC, Jochum W, Kern L, Henz S, Schneider T, Kuster GM, Lampart M, Siegemund M, Bingisser R, Schindler M, Schneiderhan- Published in: Am J Respir Crit Care Med, 2023, Page(s) 2023 Jan 1;207(1):38-49., ISSN 1097-4172 Publisher: the American Thoracic Society DOI: 10.1164/rccm.202201-0011oc Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
