Nanomaterials for Enzymatic Control of Oxidative Stress Toxicity and Free Radical Generation

Project Information

NESTOR

Grant agreement ID: 101007629

DOI

10.3030/101007629

EC signature date 20 November 2020

Start date 1 October 2021

End date 31 March 2026

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 837 200,00

EU contribution

€ 837 200,00

Coordinated by

UNIVERSIDAD DE ZARAGOZA
Spain

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Deliverables

Websites, patent fillings, videos etc. (2)

Meeting's Minute

As in all NESTOR meetings, a detailed Minute will be prepared, consensued and approved by all participants.

Public-oriented actions for dissemination

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Publications

Peer reviewed articles (26)

Biocompatible Iron Oxide Nanoparticles Display Antiviral Activity Against Two Different Respiratory Viruses in Mice

Author(s): Marta DeDiego, Yadileiny Portilla, Neus Daviu, Darío López-García, Laura Villamayor, Paula Vázquez-Utrilla, Vladimir Mulens-Arias, Sonia Pérez-Yagüe, Aitor Nogales, Jesús Ovejero, Alvaro Gallo-Cordova, Luis Enjuanes, Sabino Veintemillas-Verdaguer, M Puerto Morales, Domingo Barber
Published in: International Journal of Nanomedicine, Issue Volume 19, 2024, Page(s) 13763-13788, ISSN 1178-2013
Publisher: DOVE MEDICAL PRESS
DOI: 10.2147/ijn.s475323

Magnetic harvesting and degradation of microplastics using iron oxide nanoflowers prepared by a scaled-up procedure

Author(s): Álvaro Gallo-Córdova, Belén Corrales-Pérez, Paula Cabrero, Carmen Force, Sabino Veintemillas-Verdaguer Jesús G. Ovejero, María del Puerto Morales
Published in: Chemical Engineering Journal, Issue Volume 490, 2024, Page(s) 151725, ISSN 1385-8947
Publisher: Elsevier BV
DOI: 10.1016/j.cej.2024.151725

Magnetic nanofibers for remotely triggered catalytic activity applied to the degradation of organic pollutants

Author(s): J.A. Fuentes, B. Sanz, R. Mallada, M.R. Ibarra, G.F. Goya
Published in: Materials & Design, Issue Volume 226, 2023, Page(s) 11165, ISSN 0264-1275
Publisher: Elsevier BV
DOI: 10.1016/j.matdes.2023.111615

Vanadium incorporation in ferrite nanoparticles serves as an electron buffer and anisotropy tuner in catalytic and hyperthermia applications

Author(s): T. E. Torres, D. P. Valdés, S. Hettler, J. M. Nuñez, I. Rodrigo, I. Orue, J. Á. García, F. Plazaola, R. D. Zysler, E. Lima, M. H. Aguirre, G. F. Goya, R. Arenal
Published in: Nanoscale, Issue 17, 2025, Page(s) 10205-10218, ISSN 2040-3364
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4nr04219k

Thermographical method to assess the performance of magnetic nanoparticles in hyperthermia experiments through spatiotemporal temperature profiles

Author(s): D.P. Valdés, T.E. Torres, A.C. Moreno Maldonado, Urretavizcaya, M.S. Nadal , M. Vásquez Mansilla, R.D. Zysler, G.F. Goya, E. De Biasi, E. Lima Jr.
Published in: Physical Review Applied, Issue 19, 2023, Page(s) 014042, ISSN 2331-7019
Publisher: AMER PHYSICAL SOCONE PHYSICS ELLIPSE
DOI: 10.1103/physrevapplied.19.014042

Tailoring the magnetic and structural properties of mangenese/zinc doped iron oxide nanoparticles through microwaves-assisted polyol sythesis

Author(s): Margherita Porru, María del Puerto Morales, Alvaro Gallo-Cordova, Ana Espinosa, María Moros, Francesca Brero, Manuel Mariani, Alessandro Lascialfari, Jesús G. Ovejero
Published in: Nanomaterials, Issue 2022, 12(19), 2022, Page(s) 3304, ISSN 2079-4991
Publisher: MDPIST
DOI: 10.3390/nano12193304

Nano-pulling stimulates axon regeneration in dorsal root ganglia by inducing stabilization of axonal microtubules and activation of local translation

Author(s): Alessandro Falconieri, Pietro Folino, Lorenzo Da Palmata and Vittoria Raffa
Published in: Frontiers in Molecular Nanoscience, Issue 17, 2024, Page(s) 1340958, ISSN 1662-5099
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnmol.2024.1340958

Microtubules as a signal hub for axon growth in response to mechanical force

Author(s): Alessandro Falconieri, Allegra Coppini, Vittoria Raffa
Published in: Biological Chemistry, 2023, ISSN 1431-6730
Publisher: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/hsz-2023-0173

Next generation of nanozymes: A perspective of the challenges to match biological performance

Author(s): G. F. Goya, A. Mayoral, E. Winkler, R. D. Zysler, C. Bagnato, M. Raineri, J. A. Fuentes-García, E. Lima
Published in: Journal of Applied Physics, Issue 130/19, 2021, Page(s) 190903, ISSN 0021-8979
Publisher: American Institute of Physics
DOI: 10.1063/5.0061499

Disruption of the mitochondrial network in a mouse model of Huntington's disease visualized by in-tissue multiscale 3D electron microscopy

Author(s): Eva Martín-Solana, Laura Casado-Zueras, Teobaldo E. Torres, Gerardo F. Goya, María-Rosario Fernández-Fernández, José-Jesús Fernández
Published in: Acta Neuropathologica Communications, Issue Volume 12, 2024, Page(s) Article number: 88, ISSN 2051-5960
Publisher: BioMed Central
DOI: 10.1186/s40478-024-01802-2

Genotoxicity and heating Performance of VxFe3-xO4 nanoparticles in Health applications

Author(s): Beatriz Sanz-Sagué, Amaia Sáenz-Hernández, Ana C. Moreno Maldonado, Jesús A Fuentes-García, Jorge M. Núñez, Bojana Zegura, Alja Stern, Katja Kolosa, Iza Rozman, Teobaldo E. Torres, Gerardo F. Goya
Published in: Chemico-Biological Interactions, Issue Volume 394, 2024, Page(s) 110977, ISSN 0009-2797
Publisher: Elsevier BV
DOI: 10.1016/j.cbi.2024.110977

Insights into the formation of free radicals using metal ferrite nanocatalysts (MFe₂O₄, M = Fe, Mn, Zn, Co) prepared by a highly reproducible microwave-assisted polyol method

Author(s): Alvaro Gallo-Cordova, Nahuel Nuñez, Carlos Díaz-Ufano, Sabino Veintemillas-Verdaguer, Jimena Soler-Morala, F. Javier Palomares, Enio Lima, Elin L. Winkler, María del Puerto Morales
Published in: Nanoscale, Issue 17, 2025, Page(s) 19182-19195, ISSN 2040-3364
Publisher: Royal Society of Chemistry
DOI: 10.1039/d5nr02101d

Novel cisplatin-magnetoliposome complex shows enhanced antitumor activity via Hyperthermia

Author(s): M. Carmen Jiménez-López, Ana Carolina Moreno-Maldonado, Natividad Martín-Morales, Francisco O’Valle, M. Ricardo Ibarra, Gerardo F. Goya, Ignacio J. Molina
Published in: Scientific Reports, Issue 15, 2025, Page(s) 4780, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-025-88533-z

Mechanical stimulation prevents impairment of axon growth and overcompensates microtubule destabilization in cellular models of Alzheimer’s disease and related Tau pathologies

Author(s): Alice Alessandra Galeotti, Lorenzo Santucci, Jennifer Klimek, Mohamed Aghyad Al Kabbani, Hans Zempel, Vittoria Raffa
Published in: Frontiers in Medicine, Issue 12, 2025, Page(s) 1519628, ISSN 2296-858X
Publisher: Frontiers Media SA
DOI: 10.3389/fmed.2025.1519628

Iron oxide nanospheres: dual functionality as MRI contrast agents and magnetic fluid hyperthermia therapeutics

Author(s): Margherita Porru, Francesca Brero, Carlos Dìaz-Ufano, Manuel Mariani, Francesco Orsini, Paolo Arosio, Marìa del Puerto Morales, Alessandro Lascialfari
Published in: Dalton Transactions, Issue 54, 2025, Page(s) 9057-9068, ISSN 1477-9226
Publisher: Royal Society of Chemistry
DOI: 10.1039/d5dt00609k

Maximizing the adsorption capacity of iron oxide nanocatalysts for the degradation of organic dyes

Author(s): Carlos Díaz-Ufano, Álvaro Gallo-Córdova, Lucia Santiandreu, Sabino Veintemillas-Verdaguera, Regino Sáez, María José Torralvo Fernández, María del Puerto Morales
Published in: Colloids and Surfaces A: Physicochemical and Engineering Aspects, Issue Volume 658, 2023, Page(s) 130695, ISSN 0927-7757
Publisher: Elsevier BV
DOI: 10.1016/j.colsurfa.2022.130695

In vitro hepatic 3D cell models and their application in genetic toxicology: A systematic review

Author(s): Martina Štampar, Bojana Žegura
Published in: Mutation Research - Genetic Toxicology and Environmental Mutagenesis, Issue 900, 2024, Page(s) 503835, ISSN 1383-5718
Publisher: Elsevier BV
DOI: 10.1016/j.mrgentox.2024.503835

Magnetic induction heating-assisted synthesis of biodiesel using an alumina/iron oxide nanocatalyst

Author(s): Belén Corrales-Pérez, Gemma Vicente, María del Puerto Morales, Alvaro Gallo-Cordova
Published in: Fuel, Issue 368, 2024, Page(s) 131659, ISSN 0016-2361
Publisher: Elsevier BV
DOI: 10.1016/j.fuel.2024.131659

Maghemite and hematite nanowires synthesized by nanocasting: precursor effects on structural and magnetic properties

Author(s): Natalia I. Cuello, Emiliano G. Fornasin, Marcos I. Oliva, Gerardo F. Goya, Gustavo Marchetti, Griselda A. Eimer, Verónica R. Elías
Published in: Journal of Magnetism and Magnetic Materials, Issue 629, 2025, Page(s) 173288, ISSN 0304-8853
Publisher: Elsevier BV
DOI: 10.1016/j.jmmm.2025.173288

Onion-like Fe3O4/MgO/CoFe2O4 magnetic nanoparticles: new ways to control magnetic coupling between soft and hard magnetic phases

Author(s): Jorge M. Núñez, Simon Hettler, Enio Lima Jr, Gerardo F. Goya, Raúl Arenal, Roberto D. Zysler, Myriam H. Aguirre, Elin L. Winkler
Published in: Journal of Materials Chemistry C, Issue 2022, 10, 2022, Page(s) 15339–15352, ISSN 2050-7526
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2tc03144b

Remote-controlled activation of the release through drug-loaded magnetic electrospun fibers

Author(s): Richard Ziegler, Shaista Ilyas, Sanjay Mathur, Gerardo F. Goya, Jesús Antonio Fuentes-García
Published in: Fibers, Issue 12, 2024, Page(s) 48, ISSN 2079-6439
Publisher: MDPI
DOI: 10.3390/fib12060048

Phase Stability and Structural Evolution of Core/Shell Iron Oxide Nanoparticles Due to Oxidative Diffusion: Implications for Spintronic Applications

Author(s): Jorge M. Nuñez, Enio Lima, Javier Hernán Lohr, Marcelo Vásquez Mansilla, Roberto D. Zysler, Alfredo Tolley, Fernando Bartolomé, Javier Rubín, Simón Hettler, Raúl Arenal, Myriam Haydee Aguirre, Elin L. Winkler
Published in: ACS Applied Nano Materials, Issue 8, 2025, Page(s) 13024-13036, ISSN 2574-0970
Publisher: American Chemical Society (ACS)
DOI: 10.1021/acsanm.5c01929

Effect of temperature and copper doping on the heterogeneous Fenton-like activity of CuxFe3−xO4 nanoparticles

Author(s): Nahuel Núñez, Enio Lima Jr., Marcelo Vásquez Mansilla, Gerardo F. Goya, Álvaro Gallo-Cordova, María del Puerto Morales, Elin L. Winkler
Published in: Applied Surface Science, Issue 656(12), 2024, Page(s) 159655, ISSN 0169-4332
Publisher: Elsevier BV
DOI: 10.1016/j.apsusc.2024.159655

Effect of precursor concentration, surfactant and temperature on the size, morphology and nanostructure of zero-valent iron nanocrystals synthesised by a polyol route

Author(s): Carlos Díaz-Ufano, María del Puerto Morales, Sabino Veintemillas-Verdaguer
Published in: Colloids and Surfaces A: Physicochemical and Engineering Aspects, Issue Volume 698, 5 October 2024, 2024, Page(s) 134604, ISSN 0927-7757
Publisher: Elsevier BV
DOI: 10.1016/j.colsurfa.2024.134604

3D-printed weight holders design and testing in mouse models of spinal cord injury

Author(s): Sara De Vincentiis, Francesca Merighi, Peter Blümler, Jose Gustavo De La Ossa Guerra, Mariachiara Di Caprio, Marco Onorati, Marco Mainardi, Vittoria Raffa, Marina Carbone
Published in: Frontiers in Drug Delivery, Issue 4, 2024, ISSN 2674-0850
Publisher: Frontiers Media SA
DOI: 10.3389/fddev.2024.1397056

Low Forces Push the Maturation of Neural Precursors into Neurons

Author(s): Sara De Vincentiis; Matteo Baggiani; Francesca Merighi; Valentina Cappello; Jakub Lopane; Mariachiara Di Caprio; Mario Costa; Marco Mainardi; Marco Onorati; Vittoria Raffa
Published in: Small, Issue 19, 30, 2023, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202205871