Network Analysis in Neocortex during Passive and Active Learning

Project Information

neuronsXnets

Grant agreement ID: 101007926

DOI

10.3030/101007926

Project closed

EC signature date 9 November 2020

Start date 1 September 2021

End date 31 August 2025

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 892 400,00

EU contribution

€ 855 600,00

Coordinated by

IDRYMA TECHNOLOGIAS KAI EREVNAS
Greece

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (4)

Deep learning for prediction of L2/3 events from L4, considering local network patterns, global activity.
Changes of the whole brain connectivity and network architectures within V1 and PFC before and after learning
Neuromorphic aspects: Circuit simulations and analysis
Identification of motifs within V1 and within PFC

Data sets, microdata, etc (3)

Traces from PFC made available to the web repository
Traces from visual cortex made available to the web repository
Traces from Global brain made available to the web repository

Traces from Global brain made available to the web repository. These traces have been collected mostly from the UA and will be shared to the project. If needed, additional datasets will be collected from Harvard.

Other (2)

Software of important building blocks of the analysis, available in github for open access
International workshops at various sites

Websites, patent fillings, videos etc. (1)

Website and data repository with traces, guidelines, open source, and documentation (on-going)

Publications

Conference proceedings (5)

On Temporal Robustness & Brain-State Stability of Functional Connectivity in Mouse Primary Visual Area V1 compared to Higher Visual Area AL

Author(s): Mario Alexio Savaglio, Christina Brozi, Stelios Manolis Smirnakis, and Maria Papadopouli
Published in: IEEE International Conference on Bioinformatics and Bioengineering (BIBE), 2025
Publisher: IEEE

Neuro-inspired Ensemble-to-EnsembleCommunication Primitives for Sparse and EfficientANNs

Author(s): Orestis Konstantaropoulos, Stelios Manolis Smyrnakis, and Maria Papadopouli
Published in: 25th annual IEEE International Conference on Bioinformatics and Bioengineering, 2025
Publisher: IEEEXplore and indexed by EI/Compendex
DOI: 10.48550/arxiv.2508.14140

Disentangling Stimulus & Population Dynamics in Mouse V1: Orthogonal Subspace Decomposition for Neural Representation

Author(s): N. Tzanakis, A. Barmperis, M. A. Savaglio, I. Chourdaki, S. M. Smirnakis, and M. Papadopouli
Published in: IEEE International Conference on Bioinformatics and Bioengineering (BIBE), 2025
Publisher: IEEE

Motion Direction Decoding in Mouse V1: Predictive Power Relates to Functional Connectivity Organization

Author(s): Mario Alexios Savaglio, Christina Brozi, Eleftheria Psilou, Chryssalenia Koumpouzi, Christos Vasilakos, Spyros Nessis, Emmanouel Smyrnakis, Vasileios Akoutas, Emmanouel Koniotakis, Georgios Keliris, Ganna Palagina, Stelios Smirnakis, Maria Papadopouli
Published in: Proceedings of AREADNE Research in Encoding and Decoding of Neural Ensembles, Milos, Greece, 25-29 June 2024, 2024
Publisher: J. S. Pezaris, N. G. Hatsopoulos (editors) Proceedings of AREADNE 2024, published by The AREADNE Foundation, Inc., Cambridge, Massachusetts, USA

Direction of motion decoding in mouse V1: neuron predictive power relates to functional connectivity organization

Author(s): Mario Alexio Savaglio, Christina Brozi, Eleftheria Psilou, Chryssalenia Koumpouzi , Marianna Papadostefanaki, Christos Vasilakos, Spyros Nessis, Emmanouil Smyrnakis, Vasileios Akoutas, Georgios Keliris, Ganna Palagina, Stelios Smirnakis, Maria Papadopouli.
Published in: Proceedings of International Joint Conference on Neural Networks, Issue 2025, 2025
Publisher: International Neural Network Society

Other (9)

Dynamic Activation with Knowledge Distillation for Energy-Efficient Spiking Neural Network Ensembles

Author(s): Orestis Konstantaropoulos, Theodoris Mallios, and Maria Papadopouli
Published in: arXiv (Under submission to a conference), 2025
Publisher: arXiv preprint arXiv:2502.14023

Distinct cortical profiles underlie the common reportability of thought-free experiences

Author(s): Paradeisios Alexandros Boulakis, Anikó Kusztor, Naotsugu Tsuchiya, Thomas Andrillon, Athena Demertzi
Published in: biorxiv, Issue 16, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.10.14.681984

Direction of motion decoding in mouse V1: neuron predictive power relates to functional connectivity organization

Author(s): Christina Brozi, Eleftheria Psilou, Mario Alexio Savaglio, Chryssalenia Koumpouzi , Marianna Papadostefanaki, Christos Vasilakos, Spyros Nessis, Emmanouil Smyrnakis, Vasileios Akoutas, Georgios Keliris, Ganna Palagina, Stelios Smirnakis, Maria Papadopouli
Published in: arxiv, 2025
Publisher: arxiv

Functional Connectivity in Area V1: Identifying Neuronal Modules Withinand Across Layers

Author(s): Maria Papadopouli, Manos Koniotakis, Ioannis Smyrnakis, Marios Alexios Savaglio, Christina Brozi, Eleftheria Psilou, Ganna Palagina, Andreas Tolias, Stelios Manolis Smirnakis
Published in: Computational and Systems Neuroscience (COSYNE) Conference, 2024
Publisher: COSYNE Conference/Presentation

Effects of working memory training on cognitive flexibility, dendritic spine density and long-term potentiation in female mice

Author(s): Vasiliki Stavroulaki, Lida-Evmorfia Vagiaki, Orestis Nikolidakis, Maria Zafiri, Maria E. Plataki, Kyriaki Sidiropoulou
Published in: Biorxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.07.24.603721

Trial-by-trial inter-areal interactions in visual cortex in the presence or absence of visual stimulation

Author(s): Dianna Hidalgo, Giorgia Dellaferrera, Will Xiao, Maria Papadopouli, Stelios Smirnakis, Gabriel Kreiman
Published in: Cold Spring Harbor Laboratory, 2024
Publisher: Cold Spring Harbor Laboratory

Spatio-temporal Dynamics of Neuronal Engagement to the Micro-progression of Acute Seizures in Mouse Cortical Circuits

Author(s): Joseph Lombardo, Maria Markaki, Maria Papadopouli, Stelios M. Smirnakis
Published in: AREADNE Research in Encoding and Decoding of Neural Ensembles, 2022, 2022, Page(s) 89
Publisher: AREADNE

Properties and predictive potential of the pre-ictal oscillatory dynamics in an ex vivo model of epileptiform activity in the different hippocampal subregions

Author(s): Lida-Evmorfia Vagiaki, Dionysis Xydias, Maria Kefalogianni, Sotiris Psilodimitrakopoulos, Emmanuel Stratakis, Kyriaki Sidiropoulou
Published in: Biorxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.08.23.609340

Functionally Vonnected Neuronal Modules in area V1

Author(s): Maria Papadopouli, Vassilis Sideridis, Andreas Sapoutzis, Nikos Ntorvas, Manos Koniotakis, Ioannis Smyrnakis, Ganna Palagina, Andreas Tolias, Stelios M. Smirnakis
Published in: AREADNE Research in Encoding and Decoding of Neural Ensembles, 2022, 2022, Page(s) 42
Publisher: AREADNE

Peer reviewed articles (10)

Where is my mind? A neurocognitive investigation of mind blanking

Author(s): Thomas Andrillon, Antoine Lutz, Jennifer Windt, Athena Demertzi
Published in: Trends in Cognitive Sciences, Issue 29, 2025, Page(s) 600-613, ISSN 1364-6613
Publisher: Elsevier BV
DOI: 10.1016/j.tics.2025.02.002

Unravelling consciousness and brain function through the lens of time, space, and information

Author(s): Andrea I. Luppi, Fernando E. Rosas, Pedro A.M. Mediano, Athena Demertzi, David K. Menon, Emmanuel A. Stamatakis
Published in: Trends in Neurosciences, Issue 47, 2024, Page(s) 551-568, ISSN 0166-2236
Publisher: Elsevier BV
DOI: 10.1016/j.tins.2024.05.007

Trial-by-trial inter-areal interactions in visual cortex in the presence or absence of visual stimulation

Author(s): Dianna Hidalgo, Giorgia Dellaferrera, Will Xiao, Maria Papadopouli, Stelios Smirnakis, Gabriel Kreiman
Published in: eLife14:RP105119, 2025, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.105119

Glutamate-specific gene linked to human brain evolution enhances synaptic plasticity and cognitive processes

Author(s): Cleanthe Spanaki, Kyriaki Sidiropoulou, Zoe Petraki, Konstantinos Diskos, Xanthippi Konstantoudaki, Emmanouela Volitaki, Konstantina Mylonaki, Maria Savvaki, Andreas Plaitakis
Published in: iScience, Issue 27, 2025, Page(s) 108821, ISSN 2589-0042
Publisher: Elsevier
DOI: 10.1016/j.isci.2024.108821

Variations of autonomic arousal mediate the reportability of mind blanking occurrences

Author(s): Paradeisios Alexandros Boulakis, Nicholas John Simos, Stefania Zoi, Sepehr Mortaheb, Christina Schmidt, Federico Raimondo, Athena Demertzi
Published in: Scientific Reports, Issue 15, 2025, Page(s) 4956, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-81618-1

Classification schemes of altered states of consciousness

Author(s): Larry Douglas Fort, Cyril Costines, Marc Wittmann, Athena Demertzi, Timo Torsten Schmidt
Published in: Neuroscience & Biobehavioral Reviews, Issue 175, 2025, Page(s) 106178, ISSN 0149-7634
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2025.106178

Dynamic Functional Hyperconnectivity After Psilocybin Intake Is Primarily Associated With Oceanic Boundlessness

Author(s): Sepehr Mortaheb, Larry D. Fort, Natasha L. Mason, Pablo Mallaroni, Johannes G. Ramaekers, Athena Demertzi
Published in: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, Issue 9, 2024, Page(s) 681-692, ISSN 2451-9022
Publisher: Elsevier BV
DOI: 10.1016/j.bpsc.2024.04.001

Whole-Brain Deactivations Precede Uninduced Mind-Blanking Reports

Author(s): Paradeisios Alexandros Boulakis, Sepehr Mortaheb, Laurens van Calster, Steve Majerus, Athena Demertzi
Published in: The Journal of Neuroscience, Issue 43, 2023, Page(s) 6807-6815, ISSN 0270-6474
Publisher: Society for Neuroscience
DOI: 10.1523/jneurosci.0696-23.2023

Probing the embodiment of sleep functions: Insights from cardiac responses to word‐induced relaxation during sleep

Author(s): Matthieu Koroma, Jonas Beck, Christina Schmidt, Björn Rasch, Athena Demertzi
Published in: Journal of Sleep Research, Issue 33, 2024, Page(s) e14160, ISSN 0962-1105
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/jsr.14160

Relating mind-blanking to the content and dynamics of spontaneous thinking

Author(s): Paradeisios Alexandros Boulakis, Athena Demertzi
Published in: Current Opinion in Behavioral Sciences, Issue 61, 2025, Page(s) 101481, ISSN 2352-1546
Publisher: Elsevier Limited
DOI: 10.1016/j.cobeha.2024.101481