Description du projet
Recourir aux technologies «omiques» pour découvrir des métabolites fongiques bioactifs
Le projet H2020-MSCA-RISE GoMyTRi est parvenu à ouvrir la voie à une collaboration internationale entre trois organismes de recherche de premier plan à l’échelle mondiale, respectivement issus d’Allemagne, des Pays-Bas et de Thaïlande. Avec des partenaires spécialisés en mycologie appliquée, le projet a exploré les métabolites secondaires bénéfiques au développement d’antibiotiques, et a identifié des candidats potentiels au développement d’agents de biocontrôle fongique respectueux de l’environnement. Le projet MYCOBIOMICS, financé par l’UE, entend élargir la collaboration à des partenaires soigneusement sélectionnés d’Autriche, de République tchèque, du Kenya et d’Afrique du Sud pour mettre en œuvre les technologies et les études «omiques» concernant les interactions des organismes fongiques, de manière à découvrir de nouvelles molécules bioactives. Le projet caractérisera également le mycobiote de plantes agricoles importantes.
Objectif
The proposed project embarks on a previous collaboration in the framework of H2020-MSCA-RISE “GoMyTRi” that has successfully laid the groundwork for an international collaboration involving three worldwide leading research infrastructures from Germany, the Netherlands, and Thailand. The common research interest of the partners is basic and applied mycology, and they joined forces to explore the beneficial secondary metabolites for development of antibiotics, and to find potential candidates for development of environmentally friendly fungal biocontrol agents. The interdisciplinary training conducted in the course of “GoMyTri” has already resulted in several joint scientific publications, and some of the PhD candidates involved have graduated with excellent grades, while some of the postdoctoral researchers involved have gained valuable experience in project management. During the past years, the collaboration has been consolidated and the partners have also been changing the scope of their respective research agendas. The new proposal aims to expand the collaboration by adding further, carefully selected partners from Austria, the Czech Republic, Kenya and South Africa, which have an excellent scientific track record and bring in additional know-how and expertise. The new objectives have been expanded to the implementation of –OMICS technologies and studies on the interaction of fungal organisms in order to discover new
bioactive molecules. Furthermore, the project aims at characterization of the mycobiota of important agricultural plants. The scientists involved in the training program will thus be working in an interdisciplinary scenario that is intended to tackle several important global challenges at once and be given the opportunity to learn many important methods and techniques that are essential for studies of beneficial as well as detrimental fungal organisms. In addition, several dissemination events are planned.
Champ scientifique
Programme(s)
Régime de financement
MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)Coordinateur
38124 Braunschweig
Allemagne